Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Most home care clients rely on informal care from spouse or child

One in six people providing informal care to seniors experiences distress, according to a new study released today by the Canadian Institute for Health Information (CIHI), and those caring for seniors with moderate to severe cognitive impairment, such as those with Alzheimer's or other dementia, are most at risk.

27 Aug 2010

Mixed pathologies in brains of elderly account for memory loss and confusion

Most recent studies show that elderly people over the age of 80 often have mixed pathologies in their brains that account for their memory loss and confusion. Very few senior citizens have "pure Alzheimer disease"; therefore, this terminology should be used with caution. It now appears that vascular problems such as high blood pressure and diabetes can shrink the parts of the brain that control memory and can significantly affect at what age elderly people become demented.

27 Aug 2010

Researchers recommend traumatic brain injury reclassification for additional funding

Traumatic brain injury, currently considered a singular event by the insurance industry and many health care providers, is instead the beginning of an ongoing process that impacts multiple organ systems and may cause or accelerate other diseases and disorders that can reduce life expectancy, according to research from the University of Texas Medical Branch at Galveston.

27 Aug 2010

Study finds moderate exercise enhances DMN connectivity in specific regions of brain

A group of "professional couch potatoes," as one researcher described them, has proven that even moderate exercise - in this case walking at one's own pace for 40 minutes three times a week - can enhance the connectivity of important brain circuits, combat declines in brain function associated with aging and increase performance on cognitive tasks.

27 Aug 2010

Battery of tests for quick assessment of cognitive abilities in Down syndrome patients

Neuroscientists in the Down Syndrome Research Group at the University of Arizona have created a battery of tests that quickly aid in the assessment of the cognitive abilities of persons with Down syndrome.

27 Aug 2010

AgeneBio receives grant to develop neural stabilizer therapy for amnestic mild cognitive impairment

The Alzheimer's Drug Discovery Foundation (ADDF) announced today that it has awarded a grant of $240,000 to AgeneBio Inc. to develop a new class of small-molecules that have promise in treating amnestic mild cognitive impairment (aMCI), a neurological condition that often progresses to Alzheimer's disease and affects more than 3 million aging Americans.

27 Aug 2010

Research on myosin II protein can lead to novel treatment for memory disorders

Scientists from the Florida campus of The Scripps Research Institute have discovered a mechanism that plays a critical role in the formation of long-term memory. The findings shed substantial new light on aspects of how memory is formed, and could lead to novel treatments for memory disorders.

26 Aug 2010

Neuralstem files IND with FDA for spinal cord stem cell Phase I clinical trial for chronic spinal cord injury

Neuralstem, Inc. announced that it has filed an Investigational New Drug (IND) application with the United States Food and Drug Administration (FDA) to begin a Phase I safety clinical trial for chronic spinal cord injury with its spinal cord stem cells. This multicenter Phase I safety trial will enroll a total of 16 long-term, or chronic, spinal cord injury patients, with an American Spinal Injury Association (ASIA) Grade A level of impairment, one-to-two years post-injury.

26 Aug 2010

Type 2 diabetes, insulin resistance increases risk for Alzheimer's disease: Research

People with insulin resistance and type 2 diabetes appear to be at an increased risk of developing plaques in the brain that are associated with Alzheimer's disease, according to new research published in the August 25, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.

26 Aug 2010

Vitamin D2 in AbM mushroom can neutralize oxidative stress: Research

Total Nutraceutical Solutions, Inc., announced that it has completed a research study comparing the therapeutic effect of single nutrient forms of synthetic Vitamin D3 and D2 versus natural Vitamin D2 within a whole food. The study focused on the control of Paraquat induced oxidative stress/biologic death.

25 Aug 2010

BIO president comments on U.S. District Court injunction on embryonic stem cell research funds

Biotechnology Industry Organization (BIO) President and CEO Jim Greenwood issued the following statement today regarding the injunction issued yesterday by a U.S. District Court prohibiting the use of federal funds to support embryonic stem cell research.

25 Aug 2010

Scientists discover Magnetic Resonance Spectroscopy can rapidly diagnose degenerative disorders

Magnetic Resonance Spectroscopy can distinguish between neurological diseases in patients without clear symptoms.A team of American scientists claim that a new method of testing for neurological diseases could provide doctors with a rapid and non-invasively method of diagnosing degenerative disorders.

25 Aug 2010

Judge blocks federal funding of human embryonic stem cell research

The Washington Post: "A federal judge on Monday blocked the Obama administration from funding human embryonic stem cell research, ruling that the support violates a federal law barring the use of taxpayer money for experiments that destroy human embryos.

25 Aug 2010

New book provides vision on reforming Alzheimer's disease treatment

Although a new surge of scientific research has uncovered telltale signs of Alzheimer's disease that show up in brain scans and spinal taps, many questions remain unanswered about the clinical value of early testing and the overall direction of patient care, according to Dr. Kenneth S. Kosik, Harriman Professor of Neuroscience Research at the University of California and co-director of UCSB's Neuroscience Research Institute.

25 Aug 2010

BioScale installs ViBE analytical tool at Massachusetts-based pharmaceutical company

BioScale Inc., an innovative life science company that develops, manufactures and promotes novel analytical tools enabling advancements in protein research, today announced the first shipment and installation of the ViBE™ Protein Analysis Workstation at a major Massachusetts-based pharmaceutical company.

25 Aug 2010

Stem cell research issues fought out in the court

A US district court has issued a temporary injunction stopping President Obama’s plans to increase funding for human embryonic stem cell research. The US government will appeal. According to a Justice Department spokesman, they are likely to file a case this week.

24 Aug 2010

UNT Health Science Center analyzes DNA from unidentified human remains

Center for Human Identification at the University of North Texas Health Science Center (UNTHSC) analyzes DNA from unidentified human remains for law enforcement organizations and medical examiners across the country in an attempt to put a name to a body or victim. The result, in many cases, is resolution for family members who have spent years wondering about the fate of their loved one.

24 Aug 2010

Maria Shriver joins Alzheimer's Association to release The Shriver Report

Maria Shriver, in Partnership with the Alzheimer's Association, Takes a Groundbreaking Look into the Epidemic's Effect on Women as Caregivers, Advocates, and People Living With Alzheimer's.

24 Aug 2010

'Village' movement and community health clinics offer alternative models of care

"The village movement dates to the 2001 founding of Beacon Hill Village in Boston. This year, the Village to Village Network launched to help other communities create their own senior support groups. Other sites created to help arrange help for seniors who want to live independently at home: Senior Helpers' services include companionship, conversation, meal planning and house cleaning as well as Alzheimer's and dementia care."

23 Aug 2010

GM-CSF protein reduces AD pathology, reverses memory loss: Study

A signaling protein released during rheumatoid arthritis dramatically reduced Alzheimer's disease pathology and reversed the memory impairment of mice bred to develop symptoms of the neurodegenerative disease, a new study by the University of South Florida reports. Researchers found that the protein, GM-CSF, likely stimulates the body's natural scavenger cells to attack and remove Alzheimer's amyloid deposits in the brain.

23 Aug 2010

Alzheimer's Disease News and Research

Further Reading

Most home care clients rely on informal care from spouse or child

Mixed pathologies in brains of elderly account for memory loss and confusion

Researchers recommend traumatic brain injury reclassification for additional funding

Study finds moderate exercise enhances DMN connectivity in specific regions of brain

Battery of tests for quick assessment of cognitive abilities in Down syndrome patients

AgeneBio receives grant to develop neural stabilizer therapy for amnestic mild cognitive impairment

Research on myosin II protein can lead to novel treatment for memory disorders

Neuralstem files IND with FDA for spinal cord stem cell Phase I clinical trial for chronic spinal cord injury

Type 2 diabetes, insulin resistance increases risk for Alzheimer's disease: Research

Vitamin D2 in AbM mushroom can neutralize oxidative stress: Research

BIO president comments on U.S. District Court injunction on embryonic stem cell research funds

Scientists discover Magnetic Resonance Spectroscopy can rapidly diagnose degenerative disorders

Judge blocks federal funding of human embryonic stem cell research

New book provides vision on reforming Alzheimer's disease treatment

BioScale installs ViBE analytical tool at Massachusetts-based pharmaceutical company

Stem cell research issues fought out in the court

UNT Health Science Center analyzes DNA from unidentified human remains

Maria Shriver joins Alzheimer's Association to release The Shriver Report

'Village' movement and community health clinics offer alternative models of care

GM-CSF protein reduces AD pathology, reverses memory loss: Study

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