Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

AFFiRiS announces significant progress in collaboration with GSK for Alzheimer's vaccine development

AFFiRiS AG announced today significant progress in their collaboration with GlaxoSmithKline Biologicals for the development of an active vaccination programme against Alzheimer's disease.

1 Mar 2011

Scientists fuse human fat stem cells with rat cardiomyocytes to form new muscles

If Dr. Doolittle is famous for talking to animals, then here's a story that might make him hold his tongue: According to new research published online in The FASEB Journal, scientists have successfully fused human stem cells derived from subcutaneous adipose tissue with muscle cells from rat hearts.

1 Mar 2011

AFFiRiS AG - Alzheimer's vaccines generate further cash flow

AFFiRiS AG announced today significant progress in their collaboration with GlaxoSmithKline Biologicals (GSK) for the development of an active vaccination programme against Alzheimer´s disease. While the lead vaccine candidate AD02 is currently in phase II clinical testing, two additional preclinical programmes have been completed successfully. The second programme was related to alternative vaccine candidates generated by AFFiRiS´ AFFITOME® technology, including candidate AD03. Based on the promising preliminary results of this programme, GSK exercised its option for the alternative vaccine candidates which triggered a EUR 2.5 million payment to AFFiRiS. An additional EUR 1 million payment became due simultaneously for the successful completion of tests of alternative vaccine formulations.

28 Feb 2011

EPA approves BioNeutral's Ygiene 206 antimicrobial disinfectant

BioNeutral Group, Inc., a specialty life science technology-based company, today announced that it has received approval and registration from the Environmental Protection Agency (EPA) in response to the Company's regulatory application for its Ygiene™ 206.

28 Feb 2011

Final data from 4SC vidofludimus ENTRANCE Phase IIa trial against IBD presented at ECCO IBD Conference

4SC AG, a drug discovery and development company focused on autoimmune and cancer indications, announces the final data from the ENTRANCE Phase IIa trial in inflammatory bowel disease with vidofludimus, an oral inhibitor of interleukin-17 release and DHODH, including the secondary endpoints comprising the analysis of CDAI and CAI disease scores, change of prednisolone intake and threshold doses, safety, pharmacokinetics and biomarkers.

28 Feb 2011

Study: HT may affect symptom load and quality of life unrelated to hypothyroidism

Hashimoto's thyroiditis, an inflammatory disorder of the thyroid, is the most common cause of hypothyroidism, but a study has suggested that even when thyroid function is normal, HT may increase symptoms and decrease quality of life, as described in an article in Thyroid, a peer-reviewed journal published by Mary Ann Liebert, Inc.

27 Feb 2011

Study demonstrates ability of cobas HPV Test to detect HPV-16, HPV-18 genotypes linked to cervical cancer

Roche announced that a study published online today in the American Journal of Clinical Pathology demonstrated the ability of the cobas HPV Test to individually detect HPV-16 and HPV-18, two of the highest risk HPV genotypes causing 70 percent of cervical cancer cases.

From Roche Sequencing and Life Science 25 Feb 2011

New rapid and inexpensive test can effectively identify never-smoking group with lung adenocarcinoma

An inexpensive and rapid testing method can effectively identify a sub-group of never-smoking lung cancer patients whose tumors express a molecule associated with increased risk of disease progression or recurrence, US researchers have found.

25 Feb 2011

Refrigerated whole blood may have shelf life beyond current standard of 24 to 48 hours

In a finding that may potentially improve survival from war injuries and disasters, laboratory researchers report that refrigerated whole blood may have a shelf life well beyond the current standard of 24 to 48 hours.

24 Feb 2011

Ibio acquires Orphan Drug Designation and Fabry disease therapeutic program from Kentucky

iBio, Inc. today announced it has acquired Orphan Drug Designation for plant-produced human alpha galactosidase A and related property rights from an affiliate of Kentucky Bioprocessing LLC and has initiated a program, based on its iBioLaunch platform, to develop an improved version of the enzyme for therapy of Fabry disease.

23 Feb 2011

OptumHealth names Women & Infants Hospital of Rhode Island as Center of Excellence for Neonatal Care

For the fifth consecutive year, Women & Infants Hospital of Rhode Island has been named a Center of Excellence for Neonatal Care by the Clinical Sciences Institute of OptumHealth, an independent audit company. According to OptumHealth, not all health care providers are created equal. For complex medical conditions, the disparity is especially high.

23 Feb 2011

New DNA microarray detects genetic changes differentiating cancer patients from healthy individuals

A group of researchers led by scientists from the Virginia Bioinformatics Institute at Virginia Tech have developed a new technology that detects distinct genetic changes differentiating cancer patients from healthy individuals and could serve as a future cancer predisposition test.

23 Feb 2011

Radiologists who interpret more mammograms can determine breast cancer effectively

Radiologists who interpret more mammograms and spend some time reading diagnostic mammograms do better at determining which suspicious breast lesions are cancer, according to a new report published online on February 22 and in print in the April issue of Radiology.

22 Feb 2011

Life Technologies announces winners of European Ion Torrent PGM Sequencer Grants Program

Life Technologies Corporation, today announced Dr. Angel Carracedo and Dr. Mark Pallen as the winners of the European Ion Torrent Personal Genome Machine (PGM™) Sequencer Grants Program.

19 Feb 2011

Predictive to present results on development of real-time multiplexed PCR FGFR3 assay at ASCO 2011

Predictive Biosciences today announced that the Company will be presenting results on the development of a real-time multiplexed PCR assay for detection of FGFR3 mutations in urine and tissue at the American Society of Clinical Oncology (ASCO) 2011 Genitourinary Cancers Symposium being held February 17 - 19 in Orlando, Florida. Results will also focus on the application of the assay which is currently being used in Predictive's first commercial molecular grading product, the CertNDxTM Molecular Grading Assay.

19 Feb 2011

Phase I/II safety, efficacy data for Bellicum's BPX-101 presented at 2011 Genitourinary Cancers Symposium

Bellicum Pharmaceuticals, Inc. today announced the presentation of Phase I/II safety and efficacy data for BPX-101, a novel drug-activated dendritic cell vaccine for metastatic castrate resistant prostate cancer (mCRPC), in three separate posters at the 2011 Genitourinary Cancers Symposium held in Orlando, Florida on February 17 – 19, 2011.

19 Feb 2011

Nasal spray vs. injection -- what would you prefer?

Adelaide researchers have taken a step closer to the development of a universal flu vaccine, with results of a recent study showing that a vaccine delivered by a simple nasal spray could provide protection against influenza.

19 Feb 2011

How Huntington's disease proteins move from cell to cell

One bad apple is all it takes to spoil the barrel. And one misfolded protein may be all that's necessary to corrupt other proteins, forming large aggregations linked to several incurable neurodegenerative diseases such as Huntington's, Parkinson's and Alzheimer's.

19 Feb 2011

European Commission bans fragrance material Musk xylene, in line with global IFRA Standards

The European Commission has just announced its decision to ban the fragrance material Musk xylene under the new European Chemicals Legislation REACH, bringing EU regulations in line with the global IFRA Standards.

19 Feb 2011

Biocare, HJF sign license agreement to distribute antibody against prostate cancer

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. has signed a licensing agreement with Biocare Medical, a biotechnology company based in Concord, Calif., for the exclusive worldwide sales and distribution rights for the immunohistochemistry of an antibody designed to detect tumor prevalence in prostate cancer patients.

18 Feb 2011

Pathology News and Research

Further Reading

AFFiRiS announces significant progress in collaboration with GSK for Alzheimer's vaccine development

Scientists fuse human fat stem cells with rat cardiomyocytes to form new muscles

AFFiRiS AG - Alzheimer's vaccines generate further cash flow

EPA approves BioNeutral's Ygiene 206 antimicrobial disinfectant

Final data from 4SC vidofludimus ENTRANCE Phase IIa trial against IBD presented at ECCO IBD Conference

Study: HT may affect symptom load and quality of life unrelated to hypothyroidism

Study demonstrates ability of cobas HPV Test to detect HPV-16, HPV-18 genotypes linked to cervical cancer

New rapid and inexpensive test can effectively identify never-smoking group with lung adenocarcinoma

Refrigerated whole blood may have shelf life beyond current standard of 24 to 48 hours

Ibio acquires Orphan Drug Designation and Fabry disease therapeutic program from Kentucky

OptumHealth names Women & Infants Hospital of Rhode Island as Center of Excellence for Neonatal Care

New DNA microarray detects genetic changes differentiating cancer patients from healthy individuals

Radiologists who interpret more mammograms can determine breast cancer effectively

Life Technologies announces winners of European Ion Torrent PGM Sequencer Grants Program

Predictive to present results on development of real-time multiplexed PCR FGFR3 assay at ASCO 2011

Phase I/II safety, efficacy data for Bellicum's BPX-101 presented at 2011 Genitourinary Cancers Symposium

Nasal spray vs. injection -- what would you prefer?

How Huntington's disease proteins move from cell to cell

European Commission bans fragrance material Musk xylene, in line with global IFRA Standards

Biocare, HJF sign license agreement to distribute antibody against prostate cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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