Immune System News and Research

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New bioengineered device enhances the production of T-cells

Bone marrow transplants, also known as hematopoietic stem cell transplants, are life-saving treatments for aggressive diseases, such as leukemia and multiple myeloma, and infections such as HIV. The procedure entails infusion of blood stem cells from a matched donor into the patient to 'reset' the blood and immune system.

12 Feb 2019

Antibody-based treatment could improve cure rate for blood and immune disorders

An antibody-based treatment can gently and effectively eliminate diseased blood-forming stem cells in the bone marrow to prepare for the transplantation of healthy stem cells, according to a study in mice by researchers at the Stanford University School of Medicine.

12 Feb 2019

AbbVie, Teneobio enter into strategic transaction to develop potential treatment for multiple myeloma

AbbVie, Teneobio, Inc. and its affiliate TeneoOne, Inc. announced today that they have entered a global strategic transaction to develop and commercialize TNB-383B, a BCMA-targeting immunotherapeutic for the potential treatment of multiple myeloma.

12 Feb 2019

UMN researchers develop new way to study cancer cells in a 3D in vitro model

University of Minnesota researchers have developed a way to study cancer cells which could lead to new and improved treatment. They have developed a new way to study these cells in a 3D in vitro model (i.e. in a culture dish rather than in a human or animal).

12 Feb 2019

Research reveals critical immunological axis that triggers cancer-promoting chronic inflammation

A Massachusetts General Hospital research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation.

12 Feb 2019

HPV not likely to be transmitted through the hand, shows study

Commonly known as HPV, Human papillomavirus is a virus that infects the skin and genital area, in many cases leading to a variety of genital, anal, and oropharyngeal cancers in men and women. Strong evidence exists showing that penetrative genital sex and oral sex can transmit HPV.

12 Feb 2019

Immunotherapy drug can be effective in treating patients with recurrent brain tumors

A UCLA-led study suggests that for people with recurrent glioblastoma, administering an immunotherapy drug before surgery is more effective than using the drug afterward.

11 Feb 2019

Scientists uncover mechanism that makes aspergillus infection fatal

Researchers at the University of Jena in Germany have discovered how Aspergillus fumigatus suppresses immune defences to enable the infection to become fatal.

11 Feb 2019

Study explores patterns of adenoid and tonsil growth in teenagers

In the most thorough longitudinal study performed to date, X-ray images of children at five developmental stages between the ages of eight and nineteen were carefully measured.

11 Feb 2019

Bone marrow disease is stimulated by vitamin D and immune cells, reveals research

The bone marrow disease myelofibrosis is stimulated by excessive signaling from vitamin D and immune cells known as macrophages, reveals a Japanese research team. These findings could help to develop alternative treatments that do not target problem genes.

11 Feb 2019

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy.

11 Feb 2019

New measurable indicator could prove instrumental in fight against HIV

George Mason University's Yuntao Wu is the lead scientist on a research team that has identified a measurable indicator that could prove instrumental in the fight against HIV.

11 Feb 2019

Scientists create 3D-bioprinted brain model to study interaction with immune cells

Around a glioblastoma, a very aggressive brain tumor, cells of the human immune system start helping the tumor instead of attacking it. To do research on what happens in the interaction of these cells, scientists of the University of Twente now created a 3D-bioprinted mini model of the brain.

11 Feb 2019

Researchers find how Aspergillus fumigatus knocks out immune defenses

Research team from the University of Jena clarifies the mechanism of gliotoxin, a mycotoxin from the fungus Aspergillus fumigatus. The researchers present their findings in the current issue of the specialist journal Cell Chemical Biology

11 Feb 2019

Metabolic plasticity helps metastatic cancer cells survive hostile environments

When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments.

8 Feb 2019

Empa researchers investigate the safety of graphene for humans

Graphene, a single layer of hexagonally arranged carbon atoms, is regarded as the miracle material of the future: it is flexible, transparent, strong, can assume different electrical properties and has the highest thermal conductivity of all known materials.

8 Feb 2019