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Map of human liver cells reveals molecular make-up of individual cells

A map of the cells in the human liver has been created by University Health Network Transplant Program and University of Toronto researchers, revealing for the first time differences between individual cells at the molecular level which can have a profound impact on their behaviour in tissue, tumours and disease.

From 10x Genomics, Inc. 23 Oct 2018

New discovery may lead to better treatment options for pancreatic cancer patients

Pancreatic cancer is one of the most difficult cancers to treat and is a leading cause of cancer-related deaths. Now, Sidney Kimmel Cancer Center - Jefferson Health and Lankenau Institute for Medical Research scientists find that a gene involved in the immune system called IDO2 plays a significant role in pancreatic ductal adenocarcinoma, the most common type of pancreatic cancer.

23 Oct 2018

Salk researchers advance sonogenetics technology for treating neurological conditions

The emerging technology of sonogenetics--a technique where cells are controlled by sound--offers the potential to one day replace pharmaceutical drugs or invasive surgical treatments for neurological conditions like epilepsy, Parkinson's disease or posttraumatic stress disorder.

23 Oct 2018

Volunteering for peer counseling programs benefits people with lupus

Conventional wisdom has it that volunteering is good for you, and a study at Hospital for Special Surgery shows that to be true for people with lupus volunteering in a peer support and education program.

23 Oct 2018

Study: Targeting specific genomic mutation in breast cancer improves survival

Targeting a common mutation in patients with hormone receptor positive (HR+) HER2 negative (HER2-) advanced breast cancer with the alpha-specific phosphatidylinositol-3-kinase (PI3K) inhibitor alpelisib significantly improves progression-free survival, according to late-breaking results reported at ESMO 2018.

22 Oct 2018

Aspirin may be effective in preventing blood clots after knee replacement

When it comes to preventing blood clots after a knee replacement, good old aspirin may be just as effective as newer, more expensive drugs.

22 Oct 2018

Immunotherapy achieves major pathological response in early-stage mismatch repair deficient colon cancer

Pre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major pathological responses in 100% of early-stage colon cancers with mismatch repair deficiencies, according to results reported at ESMO 2018 from the first exploratory phase II trial to investigate this approach.

22 Oct 2018

Stratasys to showcase potential of 3D printed models at MEDICA 2018

This year’s MEDICA World Forum for Medicine (Düsseldorf, 12-15 November) will see Stratasys (Hall 9, Stand D12) demonstrate how medical institutions and their suppliers throughout the world are using advanced 3D printing across the entire value chain.

22 Oct 2018

$The International Society of Refractive Surgery honors Vivior Chairman with Casebeer Award$

The International Society of Refractive Surgery honors Vivior Chairman with Casebeer Award

Michael Mrochen, PhD, Chairman of the Board of Directors at Vivior, receives the Casebeer Award from the International Society of Refractive Surgery.

22 Oct 2018

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Genentech, a member of the Roche Group, today announced positive results from the Phase III IMpower130 study of Tecentriq (atezolizumab) plus chemotherapy (carboplatin and Abraxane® [albumin-bound paclitaxel; nab-paclitaxel]) for the initial (first-line) treatment of people with previously untreated metastatic non-squamous non-small cell lung cancer.

22 Oct 2018

Maintenance therapy with olaparib improves progression-free survival in advanced ovarian cancer patients

Two-year maintenance therapy with olaparib, a PARP (poly ADP ribose polymerase) inhibitor, olaparib, led to a substantial, unprecedented improvement in progression-free survival (PFS) in newly diagnosed patients with advanced ovarian cancer and a BRCA1 or 2 mutation, results from the phase 3 SOLO-1 trial show.

22 Oct 2018

At-home biofeedback therapy effective in relieving difficult-to-treat constipation

Biofeedback therapy used at home is about 70 percent effective at helping patients learn how to coordinate and relax bowel muscles and relieve one of the most difficult-to-treat types of constipation, investigators report.

22 Oct 2018

Study suggests rising childhood obesity rates as cause for serious hip disease in adolescents

New research suggests that rising childhood obesity rates are causing more adolescents to develop a debilitating hip disease requiring urgent surgery.

22 Oct 2018

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck's anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ or CIS plus papillary disease (Cohort A).

22 Oct 2018

Study: Erlotinib improves progression-free survival in EGFR mutated NSCLC

Neoadjuvant erlotinib benefits selected epidermal growth factor receptor (EGFR)-mutated patients who undergo complete resection of stage IIIA-N2 stage non-small cell lung cancer(NSCLC), shows a randomized study comparing erlotinib with gemcitabine plus cisplatin as neoadjuvant treatment, presented at the ESMO 2018 Congress in Munich.

22 Oct 2018

Brainlab unveils ExacTrac Dynamic at ASTRO meeting in San Antonio, Texas

Brainlab unveils ExacTrac Dynamic at the American Society for Radiation Oncology (ASTRO) meeting in San Antonio, Texas.

From Elekta 22 Oct 2018

Zoledronic acid increases disease-free survival in premenopausal women with HR+ early breast cancer

Adjuvant treatment with the bone sparing drug zoledronic acid plus hormonal therapy with the aromatase inhibitor letrozole significantly increases disease-free survival compared to tamoxifen in premenopausal women with hormone receptor positive (HR+) early breast cancer, according to results reported at ESMO 2018 Congress in Munich.

22 Oct 2018

Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus

A bioelectronic medicine device was effective in reducing pain and fatigue in patients with lupus, according to Feinstein Institute for Medical Research Professor Cynthia Aranow, MD, who will present pilot clinical trial results Tuesday at the American College of Rheumatology/Association of Rheumatology Professional's Annual Meeting.

22 Oct 2018

Finnish study finds significant regional differences in endoscopic sinus surgery

Chronic rhinosinusitis is a common disease that is usually treated with intranasal medication and nasal saline lavage. Endoscopic sinus surgery) is considered when CRS is difficult to treat. The surgery aims to restore ventilation of paranasal sinuses and reduce inflammation.

22 Oct 2018

Shorter course of trastuzumab could be an option for women with HER2+ early breast cancer

Women with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower risk of cardiac toxicity with a nine-week course of adjuvant trastuzumab compared to those treated for one year, according to a subgroup analysis of the Short-HER trial reported at ESMO 2018 Congress in Munich.

22 Oct 2018

Surgery News and Research

Map of human liver cells reveals molecular make-up of individual cells

New discovery may lead to better treatment options for pancreatic cancer patients

Salk researchers advance sonogenetics technology for treating neurological conditions

Volunteering for peer counseling programs benefits people with lupus

Study: Targeting specific genomic mutation in breast cancer improves survival

Aspirin may be effective in preventing blood clots after knee replacement

Immunotherapy achieves major pathological response in early-stage mismatch repair deficient colon cancer

Stratasys to showcase potential of 3D printed models at MEDICA 2018

The International Society of Refractive Surgery honors Vivior Chairman with Casebeer Award

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Maintenance therapy with olaparib improves progression-free survival in advanced ovarian cancer patients

At-home biofeedback therapy effective in relieving difficult-to-treat constipation

Study suggests rising childhood obesity rates as cause for serious hip disease in adolescents

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Study: Erlotinib improves progression-free survival in EGFR mutated NSCLC

Brainlab unveils ExacTrac Dynamic at ASTRO meeting in San Antonio, Texas

Zoledronic acid increases disease-free survival in premenopausal women with HR+ early breast cancer

Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus

Finnish study finds significant regional differences in endoscopic sinus surgery

Shorter course of trastuzumab could be an option for women with HER2+ early breast cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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