Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Genetic pathways explain why some people grow tall and others stay short

A landmark review in Nature Reviews Genetics dissects the rare and common genetic variants that shape human height. The paper explains how monogenic and polygenic factors converge on key growth pathways and influence disease risk.

7 Apr 2025

Hydrogel-based drug delivery offers hope for post-traumatic osteoarthritis

Post-traumatic osteoarthritis (PTOA) is a condition that affects joints after an injury. Current treatments focus on relieving symptoms but do not prevent or stop the progression of the condition.

1 Apr 2025

Queen Mary scientists invent a new way to repair osteochondral defects

Scientists at Queen Mary University of London have invented a new way to repair osteochondral defects – a common form of joint damage often caused by sports injuries or trauma – and to prevent progression to osteoarthritis.

1 Apr 2025

Altered knee joint movement after ACL surgery could contribute to early-onset knee osteoarthritis

Some individuals who have had anterior-cruciate-ligament reconstruction (ACLR), the kind of surgery often performed on athletes' knees, may develop early-onset knee osteoarthritis.

19 Mar 2025

Earlier ACL surgery may reduce risk of knee osteoarthritis

A preclinical study by HSS investigators found that earlier anterior cruciate ligament (ACL) reconstruction led to lower immune cell activity, less inflammation and fewer joint changes associated with knee osteoarthritis compared to delayed surgery.

12 Mar 2025

British scientists unveil world-leading technology to speed up drug discovery

A new 3D bio-printer that produces human-like tissue holds the potential to revolutionize the discovery of new drugs for cancer, heart disease and arthritis.

10 Mar 2025

New clinical trial tests 3D-printed devices for treating tracheobronchomalacia in infants

A new clinical trial will allow researchers to study 3D-printed bioresorbable devices aimed at treating children with rare and life-threatening airway condition tracheobronchomalacia.

6 Mar 2025

Global trends show sharp increase in osteoarthritis among postmenopausal women

The global number of cases of osteoarthritis, as well the disability associated with the condition, have risen by more than 130% over the past 3 decades among women who have gone through the menopause, indicates a data analysis spanning 1990 to 2021, and published in the open access journal BMJ Global Health.

4 Mar 2025

Genetic mutation offers hope for better rheumatoid arthritis treatments

Research led by York University's Faculty of Health reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice.

27 Feb 2025

Single-cell analysis reveals key chondrocyte subpopulations in osteoarthritis

Chondrocytes are specialized cells that are essential for cartilage maintenance and repair, and their dysfunction is central to the development of joint diseases like osteoarthritis (OA).

26 Feb 2025

Strontium-enhanced exosomes show promise for osteoarthritis treatment

Temporomandibular joint osteoarthritis (TMJOA) is a debilitating condition that causes severe joint pain, restricted mobility, and progressive cartilage degradation.

24 Feb 2025

New study reveals LRP1's crucial role in bone formation and joint development

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from complex genetic and environmental interactions that disrupt bone formation and joint development.

19 Feb 2025

E64FC26 inhibits inflammation and joint destruction in rheumatoid arthritis models

Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the endoplasmic reticulum.

10 Feb 2025

Targeting ELK3 could offer new therapy for rheumatoid arthritis

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion.

7 Feb 2025

Scientists discover new skeletal tissue with potential for regenerative medicine

A global team of scientists has made a groundbreaking discovery of a new skeletal tissue known as "lipocartilage," offering immense potential for regenerative medicine and tissue engineering.

28 Jan 2025

New treatment identified for peripheral nerve sheath tumors

A multicenter collaboration led by the Bellvitge Biomedical Research Institute (IDIBELL) - Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) identified a potential new treatment for an aggressive sarcoma arising in the nerves.

28 Jan 2025