Gut Brain Axis News and Research

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Men lose more weight than women on the keto diet, new study reveals why

Men lose more weight than women on a ketogenic diet, according to a comprehensive review in Frontiers in Nutrition. Sex differences in hormones, metabolism, and fat distribution influence the effectiveness of the ketogenic diet for obesity.

22 Jun 2025

Can a Japanese diet help with depression? Large study says yes

A large cross-sectional study of 12,499 Japanese workers found that higher adherence to traditional or modified Japanese diets was associated with a lower prevalence of depressive symptoms. The findings suggest that culturally rooted dietary patterns may support mental well-being, especially among educated adults.

18 Jun 2025

Popular painkiller use linked to gut microbiome shifts

ADHD linked to higher risk of irritable bowel syndrome, global study reveals

A global meta-analysis found that people with ADHD are significantly more likely to have irritable bowel syndrome (IBS), while the overall risk for other intestinal disorders is not increased. The findings highlight the importance of gut-brain interactions in ADHD and call for further research on microbiome-based therapies.

3 Jun 2025

Curcumin shows promise for treating obesity, inflammation, and neurodegenerative diseases

Researchers explore the medicinal role of curcumin in the treatment and prevention of neuroinflammation and metabolic disorders.

30 Apr 2025

Gut bacteria and metabolites reveal depression-linked patterns in older adults

A cross-sectional study of 400 older adults with metabolic syndrome reveals that individuals with depression have distinct gut microbiota and metabolite profiles. Eight bacterial genera and 15 fecal metabolites were significantly associated with depression, suggesting a gut-brain axis link.

29 Apr 2025

Can gut microbes help prevent Alzheimer’s?

A comprehensive review explores how gut microbiota diversity and fitness influence Alzheimer’s disease (AD) risk through neuroinflammation, amyloid and tau pathology, and blood-brain barrier dysfunction. It highlights the therapeutic potential of probiotics, dietary interventions, and omics technologies in restoring microbial balance and preventing neurodegeneration.

13 Apr 2025

Can psychedelics break compulsive eating habits in obesity?

A review by Oxford researchers explores how psychedelics like psilocybin and LSD may help disrupt compulsive eating behaviors in subsets of obese individuals. The paper outlines proposed neurobiological, epigenetic, and gut-brain mechanisms while emphasizing the need for human trials.

10 Apr 2025

Eating ultra-processed foods may rewire your brain’s hunger and reward circuits

High intake of ultra-processed foods is linked to adverse metabolic health and microstructural brain changes in regions that control appetite and reward. These effects occur both through obesity-related pathways and independently via inflammation and dyslipidemia.

9 Apr 2025

New study explores link between gut microbiome and autism spectrum disorder

Researchers evaluate the relationship between the gut microbiome and autism spectrum disorder.

2 Apr 2025

Eating ultra-processed food daily increases depression risk in older adults

Eating four or more servings of ultra-processed food daily increases the risk of depression by 10% in older adults and modestly reduces their mental health-related quality of life.

30 Mar 2025

Study uncovers bacteria's role in brain implant inflammation

Brain implants hold immense promise for restoring function in patients with paralysis, epilepsy and other neurological disorders.

18 Mar 2025

Probiotic drink kefir shows promise in preventing Alzheimer’s

Kefir, a probiotic-rich fermented milk, shows potential in reducing neuroinflammation, oxidative stress, and beta-amyloid buildup, suggesting a role in Alzheimer’s prevention and management. However, more clinical trials are needed to confirm its effectiveness in human patients.

17 Mar 2025

How your gut microbiome shapes anxiety

Researchers examine the role of the gut microbiome in the development of anxiety disorders.

12 Mar 2025

Eating ultra-processed foods harms your gut—here’s how inflammation takes hold

Ultra-processed foods disrupt gut microbiome balance, causing inflammation, reduced microbial diversity, and increased gut permeability. This microbiome imbalance contributes to chronic diseases including diabetes, IBD, cancer, and neurological disorders.

6 Mar 2025

School absenteeism could indicate functional GI disorders in kids

Children who frequently miss school because of abdominal complaints are far more likely to be suffering from disorders of the gut-brain axis such as irritable bowel syndrome than diseases that can be detected with medical tests, new UVA Health Children's research has found.

4 Mar 2025

Does a vegetarian diet help or harm your brain? Here’s what the science reveals

A recent study in Nutrients examines the effects of vegetarian and vegan diets on neurological health, highlighting both benefits and potential nutrient deficiencies that impact cognitive function.

3 Mar 2025

Researchers discover key blood molecules impacting child development

McMaster University researchers have identified small molecules in the blood that may impact early childhood development, showing how dietary exposures, early life experiences, and gut health can influence a child's growth and cognitive milestones.

28 Feb 2025

Exploring the link between cholestasis and depression

Announcing a new publication for Acta Materia Medica journal. The prevalence of depressive-like behavior is significantly higher in patients with cholestatic liver disease, leading to a notable reduction in the quality of life.

23 Feb 2025

Can chili peppers improve ADHD symptoms? Scientists explore their gut-brain connection

Chili peppers may influence ADHD symptoms by modulating the gut microbiome, with capsaicin, vitamin C, and omega-3 fatty acids showing potential effects on neurotransmitters and inflammation. However, clinical trials are needed to confirm their efficacy.

20 Feb 2025