Hypoxia News and Research

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Hypoxia is a condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the response of the tumor to the treatment.

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression.

31 Oct 2025

Oligodendrocyte progenitor cells promote blood vessel growth after stroke

Stroke is a leading cause of death and disability, affecting 1 in 4 people during their lifetime. Stroke happens when blood vessels in the brain get clogged or damaged, impairing blood flow and oxygen supply to the brain, which leads to death of neurons and other brain cells.

30 Oct 2025

Hypoxia weakens the body's infection defense by changing genetic material of neutrophils

Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body's ability to fight infection, new research shows.

28 Oct 2025

Decoding the signaling networks and metabolic dysregulation underlying sepsis

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction.

10 Oct 2025

Discovery of EUDAL reveals new mechanism behind chemotherapy resistance in oral cancer

Oral cancer is one of the most common head and neck cancers worldwide, with hundreds of thousands of new cases diagnosed every year. Despite advances in surgery, radiotherapy, and chemotherapy, survival rates remain poor.

30 Sep 2025

Novel biotechnical vector integrates viral and synthetic features for targeted cancer therapy

Gene therapy offers the possibility of addressing cancer at its molecular roots by targeting disease-causing genes rather than relying solely on surgery, chemotherapy, or radiotherapy.

16 Sep 2025

Ketogenic diets may lower migraine frequency and medication use

This narrative review argues that the migraine brain is hypometabolic, with converging evidence of mitochondrial dysfunction, impaired glucose handling, neuroinflammation, microbiome shifts, and obesity-related pathways. It proposes ketogenic diets as a plausible preventive strategy that may reduce monthly migraine days and medication use, while emphasizing the need for larger, rigorous randomized trials and careful clinical oversight.

14 Sep 2025

Natural medicines as emerging tools to target the tumor vascular microenvironment

Recent advances in cancer treatment highlight the potential of natural medicines to target the tumor vascular microenvironment, offering a novel strategy to inhibit tumor growth and metastasis.

5 Sep 2025

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.

3 Sep 2025

Can oral bacteria make heart disease worse?

The presence of viridans streptococci in coronary plaques indicates a role in atherosclerosis, potentially influencing heart disease outcomes.

1 Sep 2025

Research uncovers key role of the brain's blood flow dynamics in Alzheimer’s disease

Over seven million Americans are living with Alzheimer's disease (AD) and the heartbreaking day-to-day battle with the effects of cognitive decline.

25 Aug 2025

New insights into bone remodeling process in orthodontic tooth movement under hypoxia

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan.

25 Aug 2025

How dietary formaldehyde links to worsening diabetes and memory loss

A new review reveals how everyday foods and hidden exposures to formaldehyde may fuel insulin resistance and chip away at memory, but also points to dietary patterns and emerging therapies that could help reduce the risk.

20 Aug 2025

Omega-3 rich diet linked to lower risk of childhood myopia

A diet rich in omega-3 fatty acids, found predominantly in fish oils, may help ward off the development of short sightedness (myopia) in children, while a high intake of saturated fats, found in foods such as butter, palm oil, and red meat, may boost the risk of the condition, finds research published online in the British Journal of Ophthalmology.

20 Aug 2025

Hypoxia News and Research

Further Reading

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Oligodendrocyte progenitor cells promote blood vessel growth after stroke

Hypoxia weakens the body's infection defense by changing genetic material of neutrophils

Decoding the signaling networks and metabolic dysregulation underlying sepsis

Discovery of EUDAL reveals new mechanism behind chemotherapy resistance in oral cancer

Novel biotechnical vector integrates viral and synthetic features for targeted cancer therapy

Ketogenic diets may lower migraine frequency and medication use

Natural medicines as emerging tools to target the tumor vascular microenvironment

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Can oral bacteria make heart disease worse?

Research uncovers key role of the brain's blood flow dynamics in Alzheimer’s disease

New insights into bone remodeling process in orthodontic tooth movement under hypoxia

How dietary formaldehyde links to worsening diabetes and memory loss

Omega-3 rich diet linked to lower risk of childhood myopia

Researchers investigate how citrus bioflavonoid naringin could reduce inflammation and heart risk

Advancing cancer treatment with targeted microrobotic swarms

Conch shell blowing lowers apnea events during REM sleep

New insights into how SETD2 shapes immunity and disease

Low oxygen environment protects brain and restores movement in mice with Parkinson's

Restoring mitochondria enhances immune response against lung cancer

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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