Immunosuppression News and Research

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Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Some portions of the immune system itself have immuno-suppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.

Advancing cancer treatment with targeted microrobotic swarms

Cancer remains one of the most challenging diseases to treat, as conventional therapies like chemotherapy and radiotherapy are often hindered by poor specificity, systemic toxicity, and damage to healthy tissues.

18 Aug 2025

Lactylation drives tumor progression and immune evasion in triple negative breast cancer

Breast cancer maintains its position as the most prevalent malignancy in women worldwide, with triple-negative breast cancer (TNBC) representing the most treatment-resistant subtype due to limited therapeutic targets and frequent relapse.

18 Aug 2025

Electrophysiology-based strategies enhance cancer immunotherapy

Tumor electrophysiological abnormalities, characterized by membrane potential dysregulation, ion channel network remodeling, and microenvironmental signaling interactions, are critical drivers of malignancy.

17 Aug 2025

Genetically-engineered immune cells show promise for preventing organ rejection

A Medical University of South Carolina team reports in Frontiers in Immunology that it has engineered a new type of genetically modified immune cell that can precisely target and neutralize antibody-producing cells complicit in organ rejection.

17 Aug 2025

Implant system can treat Type 1 diabetes by supplying extra oxygen to insulin-secreting cells

Cornell researchers have developed an implant system that can treat Type 1 diabetes by supplying extra oxygen to densely packed insulin-secreting cells, without the need for immunosuppression.

11 Aug 2025

Lauric acid could be a key cancer-fighting compound in coconut oil

Virgin coconut oil and lauric acid show promise in inhibiting cancer cell growth and mitigating chemotherapy toxicity, paving the way for future therapies.

11 Aug 2025

New Swiss study probes lingering fatigue after Legionnaires' disease

Researchers in Switzerland launched the LongLEGIO study to compare the long-term health impacts of Legionnaires’ disease and other bacterial pneumonias. Baseline data reveal key differences in comorbidities and quality of life between the groups, with follow-up underway.

4 Aug 2025

New approach preserves insulin-producing cells in diabetes model

Scientific breakthroughs in one disease don't always shed light on treating other diseases. But that's been the surprising journey of one Mayo Clinic research team.

1 Aug 2025

New genetic marker improves kidney transplant match predictions

Researchers at the University of Pittsburgh have identified a new way of predicting whether a kidney donor and recipient are a good match for transplantation.

17 Jul 2025

WHO maintains global emergency status for mpox following June 2025 IHR Emergency Committee meeting

The Director-General of the World Health Organization (WHO) is hereby transmitting the report of the fourth meeting of the International Health Regulations (2005) (IHR) Emergency Committee (Committee) regarding the upsurge of mpox 2024, held on Thursday, 5 June 2025, from 12:00 to 17:00 CEST.

12 Jul 2025

TMP-SMX in early pregnancy increases risk of birth defects, new study shows

A large US cohort study found that using trimethoprim-sulfamethoxazole (TMP-SMX) for UTI in the first trimester of pregnancy was associated with a higher risk of congenital malformations compared to β-lactam antibiotics. No increased risk was seen with nitrofurantoin or fluoroquinolones.

10 Jul 2025

Assisted reproductive technology raises pregnancy risks in women with kidney transplants

Women with kidney transplants who use assisted reproductive technology (ART) to conceive might face higher risks of complications during pregnancy, according to new research from the University of Cincinnati College of Medicine.

7 Jul 2025

Researchers explore new therapies to prevent organ rejection without immunosuppressive drugs

While immunosuppressive medications are critical to prevent rejection of transplant organs, they also come with plenty of downsides.

7 Jul 2025

Amino acid metabolism in breast cancer as a driver of disease and therapeutic target

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor growth.

7 Jul 2025

Blocking key immune cells could make prostate cancer treatable

Scientists have revealed how certain immune cells may be quietly helping prostate cancer grow - and how blocking them could help the body fight back.

3 Jul 2025

New machine learning model brings transparency to risk prediction in medulloblastoma

Medulloblastoma the most common malignant pediatric brain tumor with a high risk of metastasis and poor survival outcomes.

23 Jun 2025

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

CD19-CAR T-cell treatment is a novel option of deep B cell depletion with promising results across different rheumatologic and musculoskeletal diseases (RMD).

15 Jun 2025

Recombinant zoster vaccine well tolerated by patients with inflammatory RMD

Herpes zoster (HZ) is common in older people, with a lifetime risk of 25%. The main risk factors are advanced age and immunosuppression. People with a rheumatic and musculoskeletal disease have an overall higher risk for shingles.

11 Jun 2025

Study: Deceased-donor kidney transplants do not benefit all patients equally

A major international study, being presented today at the 62nd ERA Congress, reveals that the long-accepted survival advantage of deceased-donor kidney transplantation does not extend equally to every patient and every donor organ.

5 Jun 2025

Navigating the dual role of B cells in tumor immunity

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

3 Jun 2025

Immunosuppression News and Research

Further Reading

Advancing cancer treatment with targeted microrobotic swarms

Lactylation drives tumor progression and immune evasion in triple negative breast cancer

Electrophysiology-based strategies enhance cancer immunotherapy

Genetically-engineered immune cells show promise for preventing organ rejection

Implant system can treat Type 1 diabetes by supplying extra oxygen to insulin-secreting cells

Lauric acid could be a key cancer-fighting compound in coconut oil

New Swiss study probes lingering fatigue after Legionnaires' disease

New approach preserves insulin-producing cells in diabetes model

New genetic marker improves kidney transplant match predictions

WHO maintains global emergency status for mpox following June 2025 IHR Emergency Committee meeting

TMP-SMX in early pregnancy increases risk of birth defects, new study shows

Assisted reproductive technology raises pregnancy risks in women with kidney transplants

Researchers explore new therapies to prevent organ rejection without immunosuppressive drugs

Amino acid metabolism in breast cancer as a driver of disease and therapeutic target

Blocking key immune cells could make prostate cancer treatable

New machine learning model brings transparency to risk prediction in medulloblastoma

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

Recombinant zoster vaccine well tolerated by patients with inflammatory RMD

Study: Deceased-donor kidney transplants do not benefit all patients equally

Navigating the dual role of B cells in tumor immunity

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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