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Coffee protects the brain, metabolism, and immunity at the molecular level

This review uncovers the molecular networks of coffee's compounds, showcasing their antioxidant and neuroprotective effects on immunity and metabolism.

19 Nov 2025

TRPM1 loss drives rhythmic activity across retinal diseases

Rhythmic electrical activity in the retina (known as pathological oscillations) has been observed in several eye diseases, including congenital stationary night blindness (CSNB) and retinitis pigmentosa (RP).

18 Nov 2025

Groundbreaking mouse cortex model opens new frontiers in neuroscience

Harnessing the muscle of one of the world's fastest supercomputers, researchers have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever.

17 Nov 2025

New technique revolutionizes the design of drugs that target ion channels

An international team involving the Institute of Chemical Research, a joint centre of the University of Seville and the Spanish National Research Council, has developed a new technique that will accelerate the design of drugs that target ion channels, a type of cell membrane protein involved in numerous diseases, ranging from psychiatric disorders to various types of cancer.

14 Nov 2025

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

New study reveals how the uterus senses force to drive labor

When labor begins, the uterus must coordinate rhythmic, well-timed contractions to deliver the baby safely.

13 Nov 2025

Skin-inspired sensor revolutionizes musculoskeletal monitoring

As wearable health monitoring advances, the demand for flexible pressure sensors that combine high sensitivity, full-range linearity, and medical-grade accuracy continues to grow.

13 Nov 2025

New NIH grants fuel research in oral cancer treatment and pain relief

Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have been awarded three multi-year grants totaling $6 million from the National Institutes of Health to address treatment and pain management for oral cancer.

7 Nov 2025

Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects

Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, developed an innovative strategy to construct a series of biodegradable cesium nanosalts.

4 Nov 2025

PRIME fiber-optic device can manipulate neural activity deep in the brain

Fiber-optic technology revolutionized the telecommunications industry and may soon do the same for brain research.

4 Nov 2025

Researchers visualize how brain network development is altered in rare childhood disorder

Researchers at the VIB-UAntwerp Center for Molecular Neurology have visualized how brain network development is altered in a model of KCNQ2-related developmental and epileptic encephalopathy, a rare childhood brain disorder.

31 Oct 2025

Unlocking the secrets of NMDA receptors for better brain health

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores that let charged ions enter a cell-and the molecular gatekeepers that help control them.

29 Oct 2025

First multiple sclerosis patient in the UK receives CAR T cell therapy in groundbreaking trial

A multiple sclerosis (MS) patient in the UK was the first to receive CAR T cell therapy, invented by UCL researchers, in a clinical trial testing whether this personalized treatment can slow or even halt the progression of the disease.

24 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025

World's largest-ever clinical trial launched to test treatments for Parkinson's disease

The world's largest-ever clinical trial of treatments to slow or stop the progression of Parkinson's disease has launched, led by researchers at UCL and Newcastle University.

16 Oct 2025

New adaptive finger brace could improve recovery for joint injuries

A friend's struggles with arthritis and the finger braces used to manage it inspired research by a Carnegie Mellon University student that could make it easier for patients to follow rehabilitation plans, speed up recovery times and help people manage chronic conditions.

14 Oct 2025

Chiba University study clarifies molecular mechanism driving keloid's unpredictable growth

Keloids are raised, overgrown scars that can develop after skin injuries or surgery, often extending beyond the original wound boundaries. For many people, keloids are more than just a cosmetic concern; they often cause distressing symptoms such as chronic pain, itching, and restricted movement.

9 Oct 2025

Nasal spray of gold nanoparticles delivers lithium directly to the brain

In the form of a 'nasal spray', tiny gold particles act as carriers, delivering a treatment directly to the brain: developed by scientists at the Università Cattolica Rome campus/Fondazione Policlinico Universitario A. Gemelli IRCCS, a new nanotechnological device for the treatment and prevention of neuropsychiatric and neurodegenerative diseases.

8 Oct 2025

New fluorescent molecule could be used to generate clearer images of tumors

MIT chemists have designed a new type of fluorescent molecule that they hope could be used for applications such as generating clearer images of tumors.

6 Oct 2025

How the University of Manchester used Bruker equipment to map the dynamics of complex protein

Discover how Bruker and the University of Manchester joined forces to discover more on the dynamics of complex protein.

From Bruker BioSpin Group 2 Oct 2025