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Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Amgen today announced the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) will review data supporting the supplemental New Drug Application (sNDA) for the full approval of LUMAKRAS® (sotorasib) for adults with previously treated locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC) at a meeting on Oct. 5, 2023.

From AMGEN 1 Sep 2023

More cities address ‘shade deserts’ as extreme heat triggers health issues

If it weren't for the traffic along South MacDill Avenue, Javonne Mansfield swears you could hear the sizzle of a frying pan.

28 Aug 2023

Erectile dysfunction can be a sign of undiagnosed diabetes in men under 40

Erectile dysfunction (ED) is more common in older individuals with long-term Type 2 diabetes. However, emerging research at Saint Louis University School of Medicine has found that ED indicates undiagnosed prediabetes and type 2 diabetes in young men under 40.

25 Aug 2023

The painful pandemic lessons Mandy Cohen carries to the CDC

As covid-19 devastated communities across the nation in spring 2020, a group of Black ministers in this racially divided city made an urgent plea for more testing in their neighborhoods.

23 Aug 2023

AI-based model indicates chest radiography as a potential biomarker of aging

A recent study developed an AI model to determine the age of individuals by analyzing chest radiographs.

21 Aug 2023

Most infants admitted to ICU for RSV were previously healthy, study finds

Most infants admitted to the intensive care or high acuity unit for respiratory syncytial virus (RSV) infections during fall 2022 were previously healthy and born at term, according to a new study reported in JAMA Network Open.

16 Aug 2023

Study explores the challenges of the clinical diagnoses of acute exacerbation of chronic obstructive pulmonary disease

A recent study evaluated the clinical, laboratory, and radiographic characteristics of acute exacerbations of chronic obstructive pulmonary disease (AECOPD).

16 Aug 2023

Parents and clinicians reach consensus on pediatric decision-making

How should others make decisions for pediatric patients? For decades, there has been debate in academic literature about the ethical principles that govern medical decision-making for children.

11 Aug 2023

Low levels of vitamin K linked to poor lung function

People with low levels of vitamin K in their blood are more likely to have poor lung function and to say they suffer with asthma, chronic obstructive pulmonary disease (COPD) and wheezing, according to a study published today (Thursday) in ERJ Open Research.

9 Aug 2023

Outcome markers in COPD patients with COVID-19

Researchers identify potential markers for severe COVID-19 and death in COPD patients.

8 Aug 2023

SLU research finds link between anxiety disorders, benzodiazepine exposure and dementia in seniors

Research from Saint Louis University School of Medicine finds that among patients 65 and older, a diagnosis of anxiety was significantly associated with an increased risk of dementia diagnosis, and benzodiazepine exposure was associated with a 28% increased risk of dementia.

7 Aug 2023

Millions of Americans with tobacco-related lung disease may be misdiagnosed

Millions of Americans with tobacco-related lung disease have symptoms that do not fit any existing tobacco-related disease criteria – including the most common of those, chronic obstructive pulmonary disease (COPD) – according to a new study led by researchers at UC San Francisco.

1 Aug 2023

Human senescent fibroblasts trigger fibrogenic reaction in the lungs of immunodeficient mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Human senescent fibroblasts trigger progressive lung fibrosis in mice."

31 Jul 2023

New drug delivery system may revolutionize treatment of ectopic pregnancy

Researchers in the Oregon State University College of Pharmacy have developed a drug delivery system that shows promise for greatly enhancing the efficacy of the medicine given to women with the life-threatening condition of ectopic pregnancy, which occurs when a fertilized egg implants somewhere other than the lining of the uterus.

24 Jul 2023

New campaign aims to reduce missed or delayed diagnosis of cystic fibrosis after newborn screening

Ann & Robert H. Lurie Children's Hospital of Chicago is leading an awareness campaign that aims to reduce missed or delayed diagnosis of cystic fibrosis after newborn screening, especially in non-White infants.

24 Jul 2023

Study offers a comprehensive analysis of bacterial and fungal alterations in COVID-19

Researchers use nanopore sequencing to determine the fungal and bacterial microbiota in the lungs of COVID-19 and non-COVID-19 patients.

24 Jul 2023

Flu and COVID-19 report offers latest surveillance data and public health advice

This fortnightly flu and COVID-19 report brings together the latest surveillance data along with the latest public health advice.

21 Jul 2023

Omega-3 fatty acids may help maintain lung health

Omega-3 fatty acids, which are abundant in fish and fish oil supplements, appear promising for maintaining lung health, according to new evidence from a large, multi-faceted study in healthy adults supported by the National Institutes of Health.

20 Jul 2023

Neighborhood environment can increase risk of COVID-19 hospitalization, study reveals

The range of COVID-19 symptoms varies-;some feel a mild cold, others are hospitalized, while others perish. Many studies have linked the severity of COVID-19 symptoms with an individual's biological factors, but less is known about the impact of non-biological factors, such as the environment in which people live.

14 Jul 2023

New research finds COPD diagnosis gap in African Americans

Recently published research suggests that despite showing clear symptoms of chronic obstructive pulmonary disease (COPD), many African Americans are not officially diagnosed with the disease due to flaws in diagnosis methods.

11 Jul 2023

Lung Disease News and Research

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

More cities address ‘shade deserts’ as extreme heat triggers health issues

Erectile dysfunction can be a sign of undiagnosed diabetes in men under 40

The painful pandemic lessons Mandy Cohen carries to the CDC

AI-based model indicates chest radiography as a potential biomarker of aging

Most infants admitted to ICU for RSV were previously healthy, study finds

Study explores the challenges of the clinical diagnoses of acute exacerbation of chronic obstructive pulmonary disease

Parents and clinicians reach consensus on pediatric decision-making

Low levels of vitamin K linked to poor lung function

Outcome markers in COPD patients with COVID-19

SLU research finds link between anxiety disorders, benzodiazepine exposure and dementia in seniors

Millions of Americans with tobacco-related lung disease may be misdiagnosed

Human senescent fibroblasts trigger fibrogenic reaction in the lungs of immunodeficient mice

New drug delivery system may revolutionize treatment of ectopic pregnancy

New campaign aims to reduce missed or delayed diagnosis of cystic fibrosis after newborn screening

Study offers a comprehensive analysis of bacterial and fungal alterations in COVID-19

Flu and COVID-19 report offers latest surveillance data and public health advice

Omega-3 fatty acids may help maintain lung health

Neighborhood environment can increase risk of COVID-19 hospitalization, study reveals

New research finds COPD diagnosis gap in African Americans

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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