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New EV-SELEX strategy accelerates drug discovery for wide range of GPCRs

G protein-coupled receptors (GPCRs) are the most abundantly expressed proteins in the human body, which regulate diverse physiological processes ranging from pain perception to hormone signaling.

7 Jul 2026

Blood markers reveal metabolic impact of ultra-processed food consumption

Consumption of ultra-processed food (UPF) results in a distinct metabolic 'signature' in the blood, associated with potentially adverse health conditions, a new study by an international team of researchers finds.

6 Jul 2026

New pair of techniques can speed up the search for better tuberculosis drugs

Tuberculosis, caused by the bacterium Mycobacterium tuberculosis (Mtb) is the world's deadliest single-agent caused infection, responsible for 1.23 million deaths in 2024, according to the World Health Organization.

6 Jul 2026

Cat fleas may contribute to murine typhus transmission in Texas

As human cases of flea-borne murine typhus continue to occur in South Texas, researchers are working to better understand the role cats and their fleas may play in the disease's transmission cycle.

2 Jul 2026

New high-throughput biological sensors track cellular lipid molecules

Inside every cell are lipid molecules that make up cellular membranes, helping organelles communicate and respond to stress.

2 Jul 2026

German study identifies therapeutic Achilles' heel for advanced colorectal cancer

A team led by researchers from the German Cancer Research Center (DKFZ) and the HI-STEM* Stem Cell Institute has discovered a promising new approach to treating advanced colorectal cancer.

1 Jul 2026

Botanical prebiotics may steer skin microbes toward healthier balance

Researchers tested plant-derived prebiotic candidates against selected skin-associated bacteria and found that garlic, flaxseed, and mango ginger extracts inhibited S. aureus or acne-associated C. acnes in vitro. Onion and guduchi extracts modestly promoted S. epidermidis, suggesting a microbiome-targeted skincare route that now needs validation in skin models and human studies.

30 Jun 2026

New structural insights overturn old assumptions about malaria entry

For nearly half a century, scientists have known that malaria parasites force their way into human red blood cells through a ring-shaped structure called the moving junction.

30 Jun 2026

Review links iron-dependent cell death to pathogenesis of Friedreich's Ataxia

Published in the open-access journal Ferroptosis and Oxidative Stress, the review by Giovanni Cravin and Giorgio Cozza from the University of Padua examines the growing evidence linking ferroptosis to the pathogenesis of Friedreich's Ataxia (FRDA), a rare inherited neurodegenerative disease characterized by progressive neurological decline, cardiomyopathy, and premature mortality.

30 Jun 2026

Genetic research links KDF1 mutation to impaired dental epithelial organization

Dental enamel is the hardest substance in the human body, protecting teeth from wear, temperature changes, and decay. However, enamel cannot regenerate once damaged. Inherited disorders, such as amelogenesis imperfecta, disrupt enamel formation during development, leaving affected individuals with fragile, discolored, and decay-prone teeth.

30 Jun 2026

Researchers develop new framework for dissecting the mechanics of artificial cells

What if the mechanical properties of a cell could be programmed like the components of a machine?

29 Jun 2026

Melatonin dampens fetal membrane inflammation linked to preterm birth

Melatonin reduced infection-related inflammation in human fetal membranes in an ex vivo model. The study suggests that this effect works partly through melatonin receptors and by suppressing the TLR4/MyD88/NF-κB pathway.

28 Jun 2026

Study uncovers self-propelled actin filaments that shape living cells

Every time a white blood cell engulfs a bacterium, a neuron extends a projection to connect with a neighboring cell, or when a cancer cell forcefully squeezes through tissue to spread, the cell must change its shape to accommodate the movement.

26 Jun 2026

Protein-sharing helps dormant bacteria withstand antibiotic treatment

When bacteria are under antibiotic attack, it is not 'every man for himself.' Researchers at Baylor College of Medicine and colleagues from collaborating institutions have discovered that bacterial populations work as a team to survive antibiotics.

25 Jun 2026

Aston University receives funding to develop unique cancer-fighting 'magnetobots'

Aston University has been awarded €1.2m through the Marie Skłodowska-Curie Actions (MSCA) Staff Exchanges program for a project bringing together 18 partner organizations to develop unique cancer-fighting 'magnetobots'.

25 Jun 2026

High-dose DHA reaches the brain but fails to protect memory

High-dose DHA effectively increased brain levels in older adults at Alzheimer's risk, but did not lead to cognitive or structural brain health improvements.

25 Jun 2026

Zebrafish model unlocks new insights into hereditary brain disease

CADASIL, an inherited disease caused by mutations in the NOTCH3 gene, damages the brain’s small blood vessels, leading to strokes, cognitive decline, and early dementia.

24 Jun 2026

Micro and nanorobots could transform blood clot treatment

Newer tethered devices address some of these limitations: the "milli‑spinner" thrombectomy device applies compressive and shear loading to compact a clot to about 10% of its original volume, enabling ultrafast removal even in pulmonary and cerebral arteries (in vitro and porcine studies).

23 Jun 2026

Scientists unlock molecular structure of key protein linked to cancer, neurological diseases

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases.

23 Jun 2026

Scientists discover how fat tissue drives the spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is aggressive and hard to treat. But the role of fat tissue in how the cancer spreads may help point toward new understanding and treatments, according to a new paper from scientists at the Hackensack Meridian Center for Discovery and Innovation (CDI) and colleagues at Georgetown University's Lombardi Comprehensive Cancer Center.

23 Jun 2026