Neuroimmunology News and Research

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Research reveals the role of microglia-neuron connections during brain development

The Laboratory of Neuroimmunology of the Institute of Experimental Medicine, Budapest, Hungary, led by Ádám Dénes, describes the presence of a direct interaction site between microglial cells and the cell body of developing neurons, and reveals its role during brain development.

20 Sep 2022

Understanding how microglia change their states to adapt to different areas of the brain

In this interview, News Medical speaks to Jeffrey Stogsdill, Ph.D., about his latest research exploring how microglia change their state to adapt to different areas of the brain.

2 Sep 2022

Scientists unravel the development of main immune cell population residing in the brain

New research published today by the University of Southampton shows new insight in how our brain develops, that can pave the way for treating neurological disorders.

16 Aug 2022

The brain's reaction to COVID's inflammatory tidal wave

Researchers study neuroinflammation in the cerebrospinal fluid and serum of patients infected with SARS-CoV-2.

18 Apr 2022

U of U Health researchers lead a $22-million nationwide clinical trial for rare brain disorder

University of Utah Health researchers are leading a five-year, $22-million nationwide clinical trial for NMDA receptor encephalitis––a type of autoimmune encephalitis that prompts the immune system to mistakenly attack the brain, causing confusion, memory loss, seizures, and symptoms similar to bipolar disorder and other psychiatric conditions.

1 Mar 2022

Twin study identifies the influence of environment and genetics in multiple sclerosis

Researchers at the University of Zurich and Munich's LMU Klinikum hospital have studied the immune system of pairs of monozygotic twins to identify the influence of the environment and of genetics in cases of multiple sclerosis.

16 Feb 2022

Risk of Guillain-Barré syndrome decreases after COVID-19 vaccination

A new study suggests that low GBS incidence in vaccinated patients compared to non-vaccinated people should encourage the active propagation of vaccination against SARS-CoV-2.

15 Dec 2021

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

There are few treatment options for children with multiple sclerosis - a condition in which the immune system attacks the protective covering of nerves in the brain and spinal cord - and most therapies for the disease have not been tested in children.

30 Nov 2021

NIH researchers develop a detailed cellular map of chronic MS lesions

Chronic lesions with inflamed rims, or "smoldering" plaques, in the brains of people with multiple sclerosis (MS) have been linked to more aggressive and disabling forms of the disease.

10 Sep 2021

Study in dogs may lead to better understanding of how gliomas affect the immune system

A new study reveals that high-grade gliomas, or brain tumors, in dogs contained more immune cells associated with suppressing immune response than low-grade gliomas.

20 Aug 2021

Researcher receives $8.7 million to investigate the link between viral infections and memory disorders

More than half of the survivors of West Nile virus brain infections are left with memory disorders that make everyday tasks such as remembering the route from home to work challenging.

12 Aug 2021

Young, healthy adult infected by COVID-19 suffers CNS lymphocytic vasculitis

Although COVID-19 is primarily treated as a respiratory disease, patients often experience neurological problems, such as headaches, anxiety, depression and cognitive issues, which can persist long after other symptoms have resolved.

9 Aug 2021

University of Freiburg professor honored for groundbreaking results on the brain’s immune system

The blood-brain barrier is an impenetrable barrier between the circulating blood and the brain established before birth that prevents immune cells from entering the brain from the body's immune system. Thus, the brain has its own immune system with a key actor called microglia.

21 May 2021

Simple sugar could play a key role in the development of progressive MS

Multiple sclerosis, or MS for short, manifests itself slightly differently in each person - which is why some call it "the disease of a thousand faces."

12 May 2021

Potential treatment strategies for patients suffering long-term COVID-19 symptoms

A new paper in Oxford Open Immunology, published by Oxford University Press, examines prior findings in the field of neuroimmunology that suggest potential treatment strategies for patients suffering long-term symptoms from COVID-19.

10 Feb 2021

Researchers figure out how the immune system keeps tabs on the brain

Alzheimer's disease, multiple sclerosis, autism, schizophrenia and many other neurological and psychiatric conditions have been linked to inflammation in the brain.

27 Jan 2021

Inflammation of the brain gray matter decreases nerve-cell activity in mouse model

Damage to the brain gray matter plays an important role in the progression of multiple sclerosis. This study now shows that such damage can be caused by inflammatory reactions that lead to loss of synapses, which impairs neural activity.

27 Jan 2021

Novel compound appears to protect myelin and nerve fibers

A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord.

13 Jan 2021

Chronic sleep disruption can lead to depression in adolescents, study shows

Chronic sleep disruption during adolescence can lead to depression in both males and females and alters stress reactivity in females, according to a new study led by University of Ottawa researchers.

7 Dec 2020

Study sheds new light on the biological base of psychotic symptoms

Anti-NMDAR encephalitis is an autoimmune brain illness that is often mistaken by a psychiatric disorder since it causes psychoses and other behaviour alterations. Despite having these similarities, the illness does not respond to common antipsychotic treatments.

30 Oct 2020