Prophylaxis News and Research

RSS

Legal challenge puts ACA’s preventive health services in jeopardy

A study by the Stanford Prevention Policy Modeling Lab (PPML) finds that almost 30% of privately insured individuals in the United States, or nearly 40 million people, use at least one of the free preventive health services guaranteed under the Affordable Care Act (ACA).

17 Apr 2025

Why measles is back in the U.S. and what doctors must know now

Measles is making a troubling comeback in the U.S., driven by declining vaccination rates and rising vaccine hesitancy. Pediatric infectious disease experts provide clinical guidance to help healthcare providers recognize, manage, and prevent measles in today’s outbreak-prone environment.

14 Apr 2025

Gender affirming hormone therapy reduces HIV risk for transgender people

Transgender people receiving gender-affirming hormone therapy have a 37% lower chance of acquiring HIV, and for people living with HIV, hormone therapy appears to offer a 44% lower chance of the virus remaining detectable in blood, according to a University of Michigan study.

27 Mar 2025

Machine learning model outperforms traditional methods in myelofibrosis risk stratification

A machine learning model generated by a team from the European Society for Blood and Marrow Transplantation (EBMT) outperformed standard statistical models in identifying and stratifying transplant risk for patients with myelofibrosis, according to new research published today in Blood, the American Society of Hematology's flagship journal.

27 Mar 2025

Study reveals an integrated care model for improving outcomes among people who inject drugs

Researchers from the HIV Prevention Trials Network (HPTN) presented results from the HPTN 094 ("INTEGRA") study at the 2025 Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco.

12 Mar 2025

Oral antiviral drug proves successful in preventing symptomatic COVID-19 in household members

An international clinical trial has identified a medication that can help prevent symptomatic COVID-19 in people exposed within households.

12 Mar 2025

Gilead’s capsid revolution meets our capsid solutions: Sino Biological – Engineering the tools to outsmart HIV

Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir (LEN), a groundbreaking twice-yearly injectable HIV-1 capsid inhibitor for pre-exposure prophylaxis (PrEP).

From Sino Biological Inc. 12 Mar 2025

Engineering safe and effective vaccinia virus vectors for next-generation vaccines

Announcing a new article publication for Zoonoses journal. Vaccinia virus (VACV) confers cross-protective immunity against the variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine. Despite the global eradication of smallpox in the 1980s, research efforts involving VACV have continued due to the potential threat of the variola virus being used as a bioweapon, which poses grave risks to human health.

14 Feb 2025

Single dose of antibody shields macaques from severe H5N1 influenza

National Institutes of Health (NIH) scientists and their colleagues report that a single dose of a broadly neutralizing antibody (bnAb) administered prior to virus exposure protects macaques from severe H5N1 avian influenza.

11 Feb 2025

AIM Vaccine submits mRNA RSV vaccine for FDA clinical trials

AIM Vaccine Co., Ltd., a leading PRC vaccine company, announced today that its independently developed mRNA RSV (respiratory syncytial virus) vaccine has recently been submitted for clinical trials to the U.S. Food and Drug Administration (FDA).

10 Feb 2025

Understanding infection risks in pediatric hematopoietic stem cell transplantation

Hematopoietic stem cell transplantation (HSCT) is a vital treatment for both malignant and non-malignant disorders in pediatric patients.

7 Feb 2025

Biden rule cleared hurdles to lifesaving HIV drug, but in Georgia barriers remain

Latonia Wilkins knows she needs to be on PrEP due to her non-monogamous lifestyle. But the 52-year-old Atlanta mother has faced repeated challenges getting the lifesaving drug that can prevent new HIV infections.

6 Feb 2025

Antibody therapy provides protection against severe H5N1 avian flu in monkeys

A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, University of Pittsburgh and NIH Vaccine Research Center researchers report today in Science.

30 Jan 2025

Updated guidelines for preventing and managing hepatitis B virus reactivation

Researchers update clinical practice guidelines for how to prevent and monitor hepatitis B virus reactivation.

27 Jan 2025

EU-funded Vigilant network aims to develop broad-spectrum antiviral drugs

Pandemics threaten both human health and the global economy. Vaccines are an essential part of the fight against pandemics, but they are only available months after the outbreak

23 Jan 2025

HIV drug access remains a major challenge despite promising trial results

Promising new drugs to prevent and treat HIV have the potential to transform the response to the disease. But getting these drugs to those who need it most will be critical, says Beatriz Grinsztejn, president of the International AIDS Society.

10 Jan 2025

Early results of doxy PEP rollout show mixed impact on STIs

As health care services begin offering doxycycline to prevent bacterial sexually transmitted infections (STIs), real-world evidence demonstrates that the postexposure strategy, called doxy PEP, is reducing the rate of syphilis and chlamydia, but has had little to no effect on gonorrhea and needs close monitoring for signals of antibiotic resistance.

6 Jan 2025