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Global proteomics data sharing grows fast as ProteomeXchange scales up

ProteomeXchange’s 2026 update shows that global proteomics data sharing continues to accelerate, with more than 64,000 datasets submitted and nearly half added in just the last three years. The paper also highlights how standards, reuse tools, and AI-ready resources are helping make mass spectrometry proteomics data more findable, accessible, and reusable.

20 Apr 2026

Proteomics and AI bring earlier risk prediction into sharper focus

This review examines how high-throughput proteomics is expanding precision medicine by improving biomarker discovery, disease prediction, and drug development. It also shows how AI is helping researchers interpret complex proteomic data while highlighting major barriers such as standardization, validation, and clinical translation.

19 Apr 2026

Why clinical proteomics faces a mass spectrometry vs. high-throughput profiling dilemma

This Clinical Chemistry and Laboratory Medicine review examines a central challenge in precision medicine: whether medical laboratories should prioritize metrologically sound, proteoform-resolving protein quantification by mass spectrometry or adopt scalable, affinity-based proteome profiling platforms built for high-throughput discovery and machine learning. It concludes that while emerging proteomics technologies expand diagnostic possibilities, careful validation, standardization, and quality assurance will be essential, with a hybrid path likely offering the most practical way forward.

19 Apr 2026

Researchers use tiny glass capillaries to sample living cancer cell parts

A new analytical method could improve how cancer treatments are designed - by allowing scientists to track, for the first time, exactly where inside a living cell a drug accumulates. Researchers from the University of Surrey and King's College London developed the method, which detects trace amounts of metal inside individual living cells and their internal compartments without the need to kill the cells first

17 Apr 2026

Higher stress and BMI tied to earlier puberty in girls

New research links stress, BMI, and hormone patterns to pubertal timing, revealing implications for long-term health and early intervention strategies.

16 Apr 2026

SARS-CoV-2 rarely reaches first-trimester placentas but still disrupts early pregnancy immunity

Researchers analyzing 761 first-trimester pregnancies found that SARS-CoV-2 was rarely detected in placental tissues, suggesting in utero transmission early in pregnancy is uncommon. However, maternal infection was linked to immune dysregulation at the maternal-fetal interface, altered trophoblast signaling, and inflammatory changes that could affect placental development.

14 Apr 2026

Microplastics lab studies may fail to reflect real-world exposure

Microplastics pose health risks, but lab studies often fail to reflect real-world exposure, highlighting critical gaps in toxicological research methodologies.

14 Apr 2026

How next-generation proteomics is decoding the language of life

This review examines how next-generation protein sequencing and analysis technologies are expanding proteomics beyond the limits of mass spectrometry, especially for detecting proteoforms and analyzing proteins at single-molecule resolution. It highlights maturing fluorescence-based and nanopore-based platforms that could complement existing methods and deepen insight into protein sequence, structure, function, and modification states.

13 Apr 2026

Microplastics found in human bile may be associated with gallstones

Findings show microplastics in bile may trigger cellular senescence, suggesting a link to gallstone disease and highlighting the need for further research.

9 Apr 2026

Sponge and sea slug partnership yields a new anticancer molecule with drug design promise

Researchers identified jorumycidine, a new hexacyclic marine alkaloid from the nudibranch Jorunna funebris and its dietary sponge, Haliclona sp., and demonstrated that it exhibits potent nanomolar cytotoxicity against multiple myeloma cells. They also proposed a new biosynthetic route involving cross-species metabolic interplay and an unusual oxazolidine ring that may help stabilize a pharmacologically important scaffold.

8 Apr 2026

Metformin boosts an exercise-linked metabolite and may help control weight in prostate cancer patients

Metformin raised the exercise-linked metabolite Lac-Phe in prostate cancer patients across disease stages and treatment settings, while Lac-Phe itself did not predict anticancer response. Patients in the BIMET-1 metformin arm also showed better weight management during anti-androgen therapy, highlighting a possible metabolic benefit relevant to prostate cancer care.

7 Apr 2026

Study reveals bile as reservoir for microplastics in humans

Plastic pollution has become one of the defining environmental issues of modern life, and microplastics are now known to enter the body through food, drink, and air.

6 Apr 2026

Reusable antimicrobial masks shed toxic metals during washing

Study shows reusable masks may leach harmful metals into aquatic environments, emphasizing the environmental risks of metal nanoparticles in manufacturing.

1 Apr 2026

Terahertz radiation alters metabolism and signaling in melanoma cells

Terahertz (THz) radiation is increasingly explored for biomedical applications, however, its non-thermal effects on cellular metabolism and regulatory networks remain insufficiently characterized.

28 Mar 2026

Dandelion leaves boost brain-protective compounds after digestion

Dandelion leaves are rich in polyphenols with neuroprotective effects, offering insights into natural strategies for Alzheimer's disease management.

27 Mar 2026

GC product division celebrates 70th anniversary, European and world premieres underscore progress in laboratory analytics

Today, analytica opens its doors in Munich from March 24th to 27th. Shimadzu, a global supplier of analytical measurement and testing equipment, is once again present at the world's leading trade fair – and delighted to be celebrating another anniversary so soon after its 150th birthday last year: the 70th anniversary of its gas chromatography (GC) product line.

From Shimadzu Europa GmbH 26 Mar 2026

The molecular mechanism that turns cool temps into nerve signals

When you reach into a bucket of ice, open your front door on a snowy day, or feel the tingle of menthol toothpaste, a protein in your nerve cells called TRPM8 springs into action, opening like a tiny gate to send a "cold" signal to your brain.

26 Mar 2026

New dual blood test reduces false positives in Alzheimer's screening

Alzheimer's disease is characterised by the accumulation of two proteins in the brain: amyloid-beta and tau.

23 Mar 2026

Study finds GLP-1 medicines cut fat while preserving muscle function

Researchers found that GLP-1 medicines caused weight loss mainly through fat reduction, with only modest decreases in absolute muscle mass and no disproportionate loss of muscle function. In mice, physical performance improved, while in a small 12-week human pilot trial, strength was preserved despite reduced thigh muscle size.

18 Mar 2026

New approach tracks metabolic fingerprints of tuberculosis-infected human cells

Researchers from King's College London and the University of Surrey have developed a new technique to measure the content of individual human cells infected with bacteria that model tuberculosis – and it is already revealing biological changes that conventional analysis would miss.

18 Mar 2026