Tau Protein News and Research

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Tau proteins are microtubule-associated proteins found in neurons in the brain.

Synthetic tau protein reveals key insights into protein misfolding and fibril formation

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion.

29 Apr 2025

Researchers identify gene targets that may protect against Alzheimer’s

A study published in the American Journal of Human Genetics by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital provides solutions to the pressing need to identify factors that influence Alzheimer's disease (AD) risk or resistance while providing an avenue to explore potential biological markers and therapeutic targets.

17 Apr 2025

Study explores impact of parental Alzheimer’s on tau protein spread in the brain

While some studies have suggested that having a mother with Alzheimer's disease may put you more at risk of developing the disease, a new study finds that having a father with the disease may be tied to a greater spread of the tau protein in the brain that is a sign of the disease, according to a study published on April 9, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

9 Apr 2025

A new blood test could improve how Alzheimer’s disease is diagnosed

The blood test for eMTBR-tau243 shows strong correlation with tau pathology, enhancing Alzheimer's diagnosis and monitoring cognitive decline effectively.

1 Apr 2025

Blood test offers insight into Alzheimer's stage and severity

A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden.

31 Mar 2025

Deep sleep may protect against neurodegeneration

Sleep disturbances may accelerate neurodegeneration, but whether they cause or result from disease remains unclear. Improving sleep quality could help protect against cognitive decline and brain aging.

20 Mar 2025

Probiotic drink kefir shows promise in preventing Alzheimer’s

Kefir, a probiotic-rich fermented milk, shows potential in reducing neuroinflammation, oxidative stress, and beta-amyloid buildup, suggesting a role in Alzheimer’s prevention and management. However, more clinical trials are needed to confirm its effectiveness in human patients.

17 Mar 2025

Groundbreaking stem cell therapy trial for Alzheimer's disease underway at UTHealth Houston

A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer's disease is underway at UTHealth Houston.

14 Mar 2025

Long-term NSAID use may lower dementia risk

Long-term NSAID use reduces dementia risk, particularly in those without the APOE-ε4 gene, highlighting the importance of sustained anti-inflammatory treatment over dosage levels.

9 Mar 2025

New approach to tau protein clearance offers hope for Alzheimer's treatment

USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human “mini-brains,” known as organoids.

5 Mar 2025

Researchers make breakthrough in understanding the role of tau protein in Alzheimer's

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease.

28 Feb 2025

"Normal" vitamin B12 levels may not prevent brain decline

Researchers identify associations between B12 levels currently accepted as normal and markers of neurological injury or impairment.

24 Feb 2025

Lecanemab and donanemab slow Alzheimer’s decline, but is the benefit worth the cost?

Study finds that disease-modifying therapies for Alzheimer’s, lecanemab and donanemab, can extend independence in daily activities by up to 13 months, though their clinical relevance remains debated.

17 Feb 2025

Breakthrough discovery on tau protein opens new paths for Alzheimer’s drug development

A complementary drug to combat Alzheimer's disease could target a specific part of the nerve cell protein tau.

11 Feb 2025

Novel biomarker for early prevention of Alzheimer’s disease

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering potential for timely intervention.

11 Feb 2025

New biomarker test detects early tau tangles in Alzheimer's disease

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms that litter the brain, cerebrospinal fluid and potentially blood, new research published today in Nature Medicine suggests.

10 Feb 2025

Research unveils synergistic effects of tau and beta-amyloid in Alzheimer's

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological hallmarks of Alzheimer's-tau protein and beta-amyloid-affect brain circuits in distinct yet synergistic ways, particularly those linked to memory and emotions.

6 Feb 2025