Animal Model News and Research

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Mouse model mimics clinical course and pathology observed in COVID-19 patients

A mouse model of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reproduces features observed in human patients, researchers report May 26 in the journal Cell Host & Microbe.

27 May 2020

New strategy identified to address the underlying cause of LAD1 patients' symptoms

Owing to a rare genetic mutation, individuals with leukocyte adhesion deficiency type 1 (LAD1) experience a suite of symptoms that trace back to an immune system dysfunction.

27 May 2020

Legal Cannabis hemp oil helps reduce chronic neuropathic pain in mice

Researchers examine the effectiveness of consuming hemp oil extracted from the whole Cannabis plant using a chronic neuropathic pain animal model.

20 May 2020

New animal model for COVID-19

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage the world, scientists are frantically searching for a vaccine or new drug that will effectively counter the lethal effects of the virus that leads to COVID-19 disease.

19 May 2020

CSHLP Press releases new book on heart development and disease

Cold Spring Harbor Laboratory Press (CSHLP) announced the release of Heart Development and Disease, available on its website in hardcover and eBook formats.

15 May 2020

Low-cost PCR test designed to detect coronavirus

The project of Consuelo Rubio has been among those chosen for the call of the Valencian System of Innovation and Research for the COVID-19 emergency.

14 May 2020

Research examines molecules derived from ticks as potential COVID-19 treatment option

UK-based biotechnology firm ILC Therapeutics is working alongside the University of Oxford to examine the use of Evasins – molecules derived from ticks – as a potential COVID-19 treatment option for patients whose lungs are badly damaged by the virus and face a critical juncture in recovery.

13 May 2020

Study: New combination treatment significantly improves degenerative joint diseases

Hutchinson-Gilford Progeria Syndrome (HGPS) is a fatal condition that is especially prevalent in the skin, cardiovascular and the musculoskeletal systems. There exists a wide gap between existing knowledge of the disease and a potential treatment or cure.

12 May 2020

New drugs developed for treating polycystic hepatorenal diseases

Polycystic hepatorenal diseases are hereditary, genetic disorders characterized by the progressive development of multiple symptomatic cysts in the kidneys and/or liver which may cause alterations in the function of these organs and/or complications associated with their growth.

11 May 2020

More selective elimination of leukemic and hematopoietic stem cells

Acute myeloid leukemia is an aggressive cancer of the blood-forming system. It affects the hematopoietic stem cells, or blood stem cells, of various white blood cells and of the red blood cells and platelets.

8 May 2020

The Role of Microphysiological Systems for Oncology and Stem Cell Research

In this interview, Dr. Nancy Allbritton from The Allbritton Lab talks to News-Medical and Life Sciences about the revolutionary technology and techniques for the application of new technologies for oncology and stem cell research.

From Pittcon 6 May 2020

Researchers develop a new way to treat chronic pain

Researchers from the University of Copenhagen have developed a new way to treat chronic pain which has been tested in mice. With a compound designed and developed by the researchers themselves, they can achieve complete pain relief.

30 Apr 2020

New drug formulation could be used in the treatment of Candida infections

With antimicrobial resistance (AMR) increasing around the world, new research led by the University of Bristol has shown a new drug formulation could possibly be used in antifungal treatments against Candida infections.

28 Apr 2020

Researchers develop new method for remotely stimulating activity in deep brain regions

University of Texas at Dallas researchers have developed a promising method for remotely stimulating activity in deep brain regions, advancing understanding of how molecules act in the brain and paving the way for better cancer treatments and therapies for other diseases.

27 Apr 2020

Light-based deep brain stimulation used to treat motor dysfunction in Parkinson's disease models

Biomedical engineers at Duke University have used deep brain stimulation based on light to treat motor dysfunction in an animal model of Parkinson's disease.

27 Apr 2020

Scientists elucidate novel disease processes involved in pulmonary fibrosis development

Working alongside research groups from Heidelberg, researchers from Charité - Universitätsmedizin Berlin have elucidated the novel disease processes involved in the development of pulmonary fibrosis.

27 Apr 2020

Four drugs that could halt preterm labor identified

As the number of preterm births in the U.S. continues to rise, there is an increasing need for new approaches to prevent preterm labor from progressing to preterm birth. Researchers have discovered a common molecular pathway in women who experience preterm labor and are using this insight to develop new treatments for woman who experience early labor.

27 Apr 2020