Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Blood test shows high accuracy in detecting Alzheimer's in Asian populations

A study in Alzheimer's & Dementia, a leading journal in dementia research, has demonstrated the high accuracy of plasma p-tau217 as a blood-based biomarker for detecting abnormal brain beta-amyloid (Aβ) pathology, a hallmark of Alzheimer's disease (AD).

25 Mar 2025

Simple urine test may spare kidney cancer patients from invasive scans

A simple urine test could accurately show the recurrence of kidney cancer at an early stage, potentially sparing patients invasive scans and enabling faster access to treatment, new research has shown.

24 Mar 2025

Mount Sinai-led research uncovers mechanisms behind Crohn's disease inflammation

A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn's disease, according to findings published in Science Immunology on March 21.

22 Mar 2025

Duke-NUS and NUS Medicine launch first-ever joint center to drive metabolomics research

In a strategic move for medical research and innovation, Duke-NUS Medical School and the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) have launched the Systems Metabolomics Centre (SysMeC), their first-ever joint research center.

22 Mar 2025

Cleveland Clinic study reveals insights on immune checkpoint inhibitors for colorectal cancer

A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S.

20 Mar 2025

AI predicts biological aging using steroid pathways

Researchers discuss a novel method to predict biological aging using a deep neural network based on pathways of steroidogenesis.

19 Mar 2025

Understanding the role of CD2AP in Alzheimer's disease

A groundbreaking peer-reviewed Thought Leaders Invited Review article in Brain Medicine (Genomic Press, New York) explores how CD2-associated protein (CD2AP) contributes to Alzheimer's disease (AD), one of the most devastating neurodegenerative disorders affecting millions worldwide.

19 Mar 2025

ASCOLT trial explores aspirin’s role in preventing colorectal cancer recurrence

A large-scale, international, multicentre, phase 3 clinical trial of aspirin for the secondary prevention of colorectal cancer has concluded.

17 Mar 2025

New research reveals potential path forward for glioblastoma treatment

Glioblastoma has remained one of the toughest cancers to treat, resisting even the latest advances in immunotherapy.

17 Mar 2025

Better heart health slows brain aging and lowers dementia risk, study finds

A JAMA Network Open study finds that better cardiovascular health (CVH) in older adults is linked to lower levels of neurodegenerative biomarkers, particularly neurofilament light chain (NfL). These benefits are consistent across races and especially impactful for individuals carrying Alzheimer's-related genetic risks.

16 Mar 2025

What can you do with a BioAFM instrument?

Even more answers to help understand how BioAFM can be used!

From Bruker BioAFM 14 Mar 2025

New study reveals novel multi-omics approach with unprecedented treatment response prediction in metastatic urothelial cancer

Novigenix, a leader in AI-driven healthcare solutions, has published a groundbreaking study showcasing the predictive power of its LITOSeek™ platform for immunotherapy response in metastatic urothelial cancer.

13 Mar 2025

Can red meat help women improve iron levels? New study suggests modest benefits

A systematic review and meta-analysis of 10 intervention studies found that increased red meat consumption improves hemoglobin levels in adults, particularly women, but requires ≥8 weeks to moderately boost ferritin, though clinical relevance remains uncertain compared to iron supplements.

12 Mar 2025

New treatment option for advanced thymic carcinoma shows promise

Thymic epithelial tumors are a rare group of malignancies originating in the thymus gland, that includes thymoma and thymic carcinoma.

12 Mar 2025

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review underscores its molecular complexity and clinical significance, shedding light on its dual role in tumor suppression and oncogenesis.

11 Mar 2025

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future biomarker discovery and therapeutic advancements.

11 Mar 2025

New test could predict life-threatening side effects of cancer immunotherapy

Medical researchers in Japan have discovered a way to predict a potentially life-threatening side effect of cancer immunotherapy before it occurs.

10 Mar 2025

Combination of Epstein-Barr virus antibodies and genes linked to increased risk of MS

In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.

10 Mar 2025

Individualized treatment strategies may be the key to managing pediatric POTS

Postural orthostatic tachycardia syndrome (POTS) is a form of chronic orthostatic intolerance that primarily affects children and adolescents, leading to debilitating symptoms like lightheadedness, blurred vision, and fatigue upon standing.

10 Mar 2025