Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Social connections may boost immunity and reduce disease risk

Interactions with friends and family may keep us healthy because they boost our immune system and reduce our risk of diseases such as heart disease, stroke and type 2 diabetes, new research suggests.

3 Jan 2025

Lithocholic acid enhances health and lifespan, mimicking calorie restriction

Lithocholic acid (LCA), a metabolite induced by calorie restriction (CR), activates AMPK and mimics anti-aging benefits. A recent study highlights LCA's role in improving muscle performance, glucose tolerance, and lifespan in aged organisms.

1 Jan 2025

Insulin degradation uncovered as a new driver of resistance

Researchers reveal insulin resistance may be driven by insulin degradation during transit in the bloodstream, challenging the belief that cell defects are the primary cause.

22 Dec 2024

Subjective walking speed is a quick, equipment-free tool for identifying metabolic health risks

The study reveals a strong association between walking speed and metabolic disease risk in obesity, suggesting fast walking as a vital health intervention.

20 Dec 2024

Annona squamosa extracts show promise in treating pain and arthritis

In Brazil, researchers have identified substances with analgesic, anti-inflammatory, anti-hyperalgesic (against persistent pain) and anti-arthritic activity in the leaves of Annona squamosa, a tree popularly known in the country as fruta-do-conde or pinha.

20 Dec 2024

The role of phytochemicals in combating metabolic diseases

This editorial reviews the impact of phytochemicals on metabolic diseases, emphasizing their potential in reducing inflammation and improving health outcomes.

19 Dec 2024

Researchers investigate oxygen's effect on overactive cells in type 2 diabetes

Researchers from the University of Missouri are studying potential therapies to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes.

18 Dec 2024

Could microalgae fermentation create the superfoods of the future?

Microalgae fermentation unlocks sustainable and nutritious food production, offering bioactive peptides with antidiabetic properties but faces challenges in consumer acceptance.

18 Dec 2024

How a duty to spend wisely on worker benefits could loosen PBMs’ grip on drug prices

Ann Lewandowski knows all about pharmacy benefit managers, or PBMs, the companies that shape the U.S. drug market. Her job, as a policy advocate at drugmaker Johnson & Johnson, was to tell patient and physician groups about the PBMs' role in high drug prices.

18 Dec 2024

Scientists discover key protein that helps cancer cells evade CAR T cell therapy

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, have collared a tricky culprit that helps cancer cells evade CAR T cell therapy.

17 Dec 2024

Dual screening for liver fibrosis and retinopathy in type 2 diabetes

Retina scanning with vibration-controlled transient elastography could predict metabolic dysfunction-associated steatotic liver disease.

17 Dec 2024

Danish studies find increased risk of optic nerve damage with diabetes medicine

Two independent studies from the University of Southern Denmark (SDU) show that patients with type 2 diabetes who are treated with the drug Ozempic have an increased risk of developing damage to the optic nerve of the eye, which can lead to severe and permanent loss of vision.

16 Dec 2024

Obesity prevalence and BMI decrease in the US for the first time in a decade

Obesity prevalence in the US decreased in 2023, with significant drops in the South, highlighting the impact of GLP-1RA medications on health trends.

16 Dec 2024

Revolutionizing MASLD treatment with GLP-1 receptor agonists

Researchers explore the therapeutic potential and clinical insights of GP1-RAs in the management of metabolic dysfunction-associated steatotic liver disease.

16 Dec 2024

Metabolomic biomarkers improve diabetes risk prediction accuracy

Researchers developed a novel diabetes risk score integrating traditional factors with metabolomic biomarkers, achieving improved prediction accuracy for 10-year type 2 diabetes risk.

12 Dec 2024

New study identifies potential target for treating diabetic cardiomyopathy

Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which is slow and cannot be directly attributed to hypertension or other cardiovascular disorders.

12 Dec 2024

Gene therapy to prevent stillbirth and premature delivery developed

Researchers investigate the effectiveness of placental nano-based insulin-like 1 growth factor gene therapy to correct fetal growth restriction.

12 Dec 2024

Study reveals gut microbiome’s person-specific role in glycemic sensitivity

Research reveals how individual gut microbiota responses to high-carbohydrate diets influence glycemic sensitivity, paving the way for personalized nutrition.

11 Dec 2024

Scientists identify potential therapeutic targets for diabetic kidney disease

New potential therapeutic targets have been identified for diabetic kidney disease (DKD) - the leading cause of kidney failure in the world - that could see patients treated with new gene and drug therapies preventing the disease's progression into end stage kidney failure.

10 Dec 2024

Shivering for 1 hour a day may boost glucose tolerance and metabolic health

Daily cold exposure with shivering for 10 days improves glucose tolerance and metabolic health in individuals with obesity, highlighting shivering's role.

10 Dec 2024