Inflammation News and Research

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IL-6 blocker use in severe COVID-19 increases risk of secondary infections

With many hundreds of thousands of deaths due to the current COVID-19 pandemic, there is a rush to find an effective vaccine or drug against the virus. A new study on the preprint server medRxiv* in May 2020 shows that the use of some biologically plausible drugs may be counterproductive, and care should be taken when trying out unproven therapies.

22 May 2020

Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia

As the world struggles to overcome the current COVID-19 pandemic with non-pharmacological interventions, in the absence of an effective drug or vaccine, existing immunomodulators are being repurposed. A new study published on the preprint server medRxiv* in May 2020 shows no clinical benefit to the use of one such drug, called interferon beta 1b (IFN beta1b).

22 May 2020

Santen’s VEKTIS study demonstrates efficacy and tolerability of cyclosporine A cationic emulsion in pediatric vernal keratoconjunctivis, over 12 months

Santen EMEA is delighted to announce that the results of VEKTIS, a twelve month study in pediatric vernal keratoconjunctivitis have been published in the American Journal of Ophthalmology.

From Santen Pharmaceutical Co., Ltd. 22 May 2020

New cooling insole helps reduce risk factor for diabetic foot ulcers

A new cooling insole developed by UT Southwestern scientists reduced the foot temperature of patients with diabetic neuropathy by several degrees, diminishing a significant risk factor for diabetic foot ulcers.

21 May 2020

Adding an array of spices to a meal may help reduce inflammation

Adding an array of spices to your meal is a surefire way to make it more tasty, but new Penn State research suggests it may increase its health benefits, as well.

21 May 2020

Environmental chemicals linked to changes in the gut microbiome and health

The microbes that inhabit our bodies are influenced by what we eat, drink, breathe and absorb through our skin, and most of us are chronically exposed to natural and human-made environmental contaminants.

21 May 2020

Airway and Celonic collaborate to produce AT-100 as therapeutic candidate against COVID-19

Airway Therapeutics, Inc., a biopharmaceutical company developing a new class of biologics to break the cycle of injury and inflammation for patients with respiratory and inflammatory diseases, and Celonic Group, a premium biopharmaceutical CDMO specialized in the development and production of Advance Therapy Medicinal Products (ATMPs) and mammalian cell line-expressed biotherapeutics, today announced a collaboration to produce the novel human recombinant protein AT-100 (rhSP-D) as a therapeutic candidate against COVID-19.

21 May 2020

Excessive blood clotting and stroke in COVID-19 patients

The coronavirus disease COVID-19 is causing excessive blood clotting and stroke in young and healthy people, a new study has found.

21 May 2020

Scientists create a detailed map of how carcinogens trigger breast cancer development

In the most comprehensive review to date of how breast cancer develops, scientists have created a detailed map that describes the many ways in which environmental chemicals can trigger the disease.

21 May 2020

Does abdominal fat affect COVID-19 outcomes?

As the COVID-19 pandemic seems to be slowing down in some parts of the world slightly but accelerating in others, scientists are investigating the role played by a host of factors that might impact the final outcome. A new study published on the preprint server medRxiv* in May 2020 examines the role of abdominal fat (visceral obesity, VO) in severe COVID-19.

21 May 2020

Researchers receive $5.75 million to study link between obesity, inflammation and pancreatic cancer

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center and peer institutions has been awarded a $5.75 million grant from the National Cancer Institute to study the correlation between obesity, inflammation and pancreatic cancer.

21 May 2020

Bariatric surgery may alter gene expression in fat tissue

Altered gene expression in fat tissue may help explain why individuals who have regained weight after weight loss surgery still experience benefits such as metabolic improvements and a reduced risk of type 2 diabetes.

21 May 2020

Scientists use new model to develop cancer stem cells

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma (HCC).

21 May 2020

Producing virus-specific antibodies after COVID-19

In order to design effective vaccines for COVID-19, we need to understand our immune responses. News-Medical speaks to Professor Chen Dong to find out more.

21 May 2020

Research looks at COVID-19 in cancer patients

As the world grapples with the COVID-19 pandemic, new questions arise as to the risk posed by the virus to different patient populations, including the elderly and those with underlying disease. A new study published on the preprint server medRxiv* in May 2020 deals with the risk of COVID-19 in the subgroup of patients with cancer.

21 May 2020

Drug combination could eliminate side effects of largely abandoned diabetes treatment

A new UT Southwestern study shows how an effective but largely abandoned treatment for Type 2 diabetes could be used again in combination with another drug to eliminate problematic side effects.

20 May 2020

Certain corticosteroid could improve severe COVID-19, say researchers

Researchers at Wayne State University and Henry Ford Health System in Michigan have conducted a study indicating that the corticosteroid methylprednisolone could improve outcomes among patients with severe coronavirus disease 2019 (COVID-19).

20 May 2020

Dana-Farber launches clinical test of blood cancer drug in COVID-19 patients

Scientists at Dana-Farber Cancer Institute have launched a clinical test of a blood cancer drug in patients infected with the COVID-19 virus. T

20 May 2020

Doctoral candidate receives NIH fellowship to study how adenovirus affects heart function

A dose of adenovirus hits most people like a common cold - a cough, a fever, maybe a sore throat. But for an unfortunate few, the usually benign bug hacks the heart's cellular electrical communication system and sometimes proves fatal.

20 May 2020

Diagnosis and treatment of nonalcoholic fatty liver disease

Gastroenterology, the official journal of the American Gastroenterological Association (AGA), has released a special issue providing clinicians and researchers an up-to-date resource on the risk factors, natural history, diagnosis and treatment of nonalcoholic fatty liver disease (NAFLD).

20 May 2020