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Inhibiting energy production in immune T-cells allows some tumors to escape treatment

A small molecule that inhibits energy production in immune T-cells allows some tumors to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife.

3 Mar 2020

Supplying nutritional amino acid restores spatial memory in mouse model of Alzheimer's

Scientists at the Laboratoire des Maladies Neurodégénératives and the Neurocentre Magendie have just shown that a metabolic pathway plays a determining role in Alzheimer's disease's memory problems.

3 Mar 2020

Scientists find link between immune system and high blood pressure in patients with CKD

Detecting threats, sending out response molecules, and altering gene expression--our immune system works tirelessly day and night to protect us from invading pathogens and maintain general health and wellbeing.

3 Mar 2020

The changing face of the COVID-19 epidemic

The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus, which hit China with the disease now named COVID-19 in December 2019 and has since spread to over 70 countries, has caused over 90,000 cases, and 3,117 fatalities, with 95% or more of both being in China.

2 Mar 2020

How cannabis interacts with medications

A new practice guideline published in the journal CMAJ in February 2020 describes five types of drug interactions possible with the use of cannabis. Cannabis is a plant-derived drug containing the psychoactive ingredient delta-9-tetrahydrocannabinol (THC) and non-psychoactive cannabidiol (CBD). These cannabinoids are broken down by the liver enzymes cytochrome P450 C(YP)34A, and CYP2CC9.

2 Mar 2020

Challenges for translating pharmacomicrobiomics to personalized medicine

A new Commentary identifies three actionable challenges for translating pharmacomicrobiomics to personalized medicine in 2020.

2 Mar 2020

Tapping pre-existing immunity to enhance therapeutic cancer treatment

A new research from the University of Helsinki showed for the first time how the pre-immunization acquired through common childhood vaccines can be used to enhance therapeutic cancer treatment.

2 Mar 2020

New inhalation therapy could relieve lung fibrosis in mice and rats

A new study published in the journal Nature Communications in February 2020 shows that secretions from stem cells in the lung can be utilized to nebulize injured lungs due to several types of lung fibrosis in rats and mice. This could well result in the development of less invasive and more effective therapies for lung fibrosis.

1 Mar 2020

Drug for Ebola and MERS effective against COVID-19

A new study published in the Journal of Biological Chemistry has revealed that drug Remdesivir could be useful in treating the deadly COVID-19 or the novel coronavirus that is infecting tens of thousands of people across the world.

1 Mar 2020

Boehringer Ingelheim and Trutino enter into research collaboration to advance cytokine therapies

Boehringer Ingelheim and Trutino Biosciences today announced they have entered into a research collaboration and worldwide licensing agreement based on Trutino’s innovative On-Demand-Cytokine platform.

From Boehringer Ingelheim International GmbH 28 Feb 2020

New templates for improving assessment of senior cancer patients

While older adults, defined as those 65 and older, make up the largest percentage of cancer patients and survivors, this group is not adequately represented in clinical trials, research at the University of Cincinnati has shown.

28 Feb 2020

New radiotracer to improve image-based differential diagnostics of Parkinson’s disease

An interdisciplinary team from the Institute of Radiopharmaceutical Cancer Research headed by Prof. Peter Brust has won HZDR's (Helmholtz-Zentrum Dresden-Rossendorf) third Innovation Contest.

27 Feb 2020

Boosting immune cells to treat eczema

A new drug regimen is reported to have marked benefits in treating the troublesome and distressing skin condition called eczema. The study, published in February 2020 in the journal Science Translational Medicine, shows that boosting the levels of a type of immune cell called natural killer cells can be a more effective way to treat eczema in a mouse study.

27 Feb 2020

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

A new phase II trial finds that a combination of radiation therapy and immunotherapy led to encouraging survival outcomes and acceptable toxicity for patients with locally advanced head and neck squamous cell carcinoma

27 Feb 2020

Renishaw completes main part of Phase 1-2 clinical trial along with Herantis Pharma for treatment of Parkinson’s disease

Global engineering technologies company, Renishaw, announces that its award-winning intraparenchymal drug delivery device, has played a critical role in a joint Phase 1-2 clinical study with Herantis Pharma plc, for the investigation of cerebral dopamine neurotrophic factor (CDNF)as a treatment for Parkinson's disease.

27 Feb 2020

A retrospective review of 5,000 non-surgical rhinoplasties performed to date

As patients continue to seek non-invasive treatments across the cosmetic spectrum, "liquid rhinoplasty" is emerging as the non-surgical alternative to the traditional nose job.

27 Feb 2020

Chronic cough could be eased with new drug

A pair of studies have shown that chronic cough and its distressing symptoms could be eased with the help of a new drug. Also, the drug does not have side effects that can restrict its use, explain the researchers. The results of the two studies are published in The Lancet Respiratory Medicine, and the European Respiratory Journal, respectively.

26 Feb 2020

Coronavirus vaccine trials commence

The coronavirus disease (COVID-19) outbreak has swept the world, killing 2,770 people and infecting more than 81,000. Amid the health crisis, scientists from across the globe are racing to develop novel therapies and vaccines in the hope of stemming the spread of the deadly virus.

26 Feb 2020

Renishaw Announces Completion of the Main Part of a Multi-Centre Clinical Trial Jointly Undertaken with Herantis Pharma plc for the Treatment of Parkinson’s Disease Patients

Renishaw, announces that its drug delivery device has played a critical role in the investigation CDNF as a treatment for Parkinson's disease.

From Renishaw plc - Additive Manufacturing for Healthcare Applications 26 Feb 2020

Clinical trial to evaluate safety, efficacy of remdesivir in adults with COVID-19 begins

A randomized, controlled clinical trial to evaluate the safety and efficacy of the investigational antiviral remdesivir in hospitalized adults diagnosed with coronavirus disease 2019 (COVID-19) has begun at the University of Nebraska Medical Center in Omaha.

25 Feb 2020

Efficacy News and Research

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

Supplying nutritional amino acid restores spatial memory in mouse model of Alzheimer's

Scientists find link between immune system and high blood pressure in patients with CKD

The changing face of the COVID-19 epidemic

How cannabis interacts with medications

Challenges for translating pharmacomicrobiomics to personalized medicine

Tapping pre-existing immunity to enhance therapeutic cancer treatment

New inhalation therapy could relieve lung fibrosis in mice and rats

Drug for Ebola and MERS effective against COVID-19

Boehringer Ingelheim and Trutino enter into research collaboration to advance cytokine therapies

New templates for improving assessment of senior cancer patients

New radiotracer to improve image-based differential diagnostics of Parkinson’s disease

Boosting immune cells to treat eczema

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

Renishaw completes main part of Phase 1-2 clinical trial along with Herantis Pharma for treatment of Parkinson’s disease

A retrospective review of 5,000 non-surgical rhinoplasties performed to date

Chronic cough could be eased with new drug

Coronavirus vaccine trials commence

Renishaw Announces Completion of the Main Part of a Multi-Centre Clinical Trial Jointly Undertaken with Herantis Pharma plc for the Treatment of Parkinson’s Disease Patients

Clinical trial to evaluate safety, efficacy of remdesivir in adults with COVID-19 begins

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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