Protein C News and Research

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‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

In studies with mouse and human tissue, as well as live mice, Johns Hopkins Medicine researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson's disease.

19 May 2022

New study reveals the genetic mechanism behind severe staphylococcal infections

A common culprit of skin and respiratory infections, Staphylococcus aureus is highly unpredictable. Between 20 and 30 percent of people carry quiet colonies on their skin and in their nostrils, which seldom cause problems beyond the occasional rash.

19 May 2022

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Researchers analyze the mechanisms by which two SARS-CoV-2 accessory proteins, ORF3a and ORF7a, can downregulate the expression of MHC-I.

19 May 2022

Researchers explore SARS-CoV-2 infection in lung myeloid cells

Scientists discuss how SARS-CoV-2 utilizes myeloid cells to allow for the subsequent viral colonization in the lungs.

19 May 2022

Scientists investigate relevance of COVID-19 vaccine-mediated T cell immunity to SARS-CoV-2 variants

Researchers showed the significance of T cell-based immunity against the SARS-CoV-2 variants exhibiting evasion to antibody-centric immunity.

19 May 2022

New study helps to better understand re-infection rates and correlates of protection for SARS-CoV-2

By uniting research from 8 cohorts across the U.S., a group of researchers has accelerated collection of data integral in answering questions about immune responses needed for long lasting protection from SARS-CoV-2.

19 May 2022

Study finds Omicron variant is more stable than its ancestral strain on smooth and porous surfaces

The current study strongly indicates that it is highly likely that the Omicron variant spreads via the fomite route.

19 May 2022

Micro Products with Macro Impact; The Role of Microplate Readers in Life Sciences

In this interview, we speak to Martin Mangold, an applications specialist at BMG LABTECH, about their microplate readers and the essential role they play within life sciences research.

From BMG LABTECH GmbH 19 May 2022

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

In a new study, researchers evaluated the ability of vaccine-induced antibodies to recognize and neutralize various SARS-CoV-2 variants of concern in SARS-CoV-2-naive health care workers in the Netherlands.

19 May 2022

Study investigates the detection of antibodies against SARS-CoV-2 in urine

Researchers developed an enzyme-linked immunosorbent assay to detect antibodies against SARS-CoV-2 in urine samples.

19 May 2022

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Glioblastomas (GBMs) are highly aggressive cancerous tumors of the brain and spinal cord. Brain cancers like GBM are challenging to treat because many cancer therapeutics cannot pass through the blood-brain barrier, and more than 90 percent of GBM tumors return after being surgically removed, despite surgery and subsequent chemo- and radiation therapy being the most successful way to treat the disease.

19 May 2022

Study explores polyfunctionality of BNT162b2 COVID-19 vaccine-induced memory T-cells

Researchers assessed the impact of the BNT162b2 SARS-CoV-2 vaccine-induced memory T cells on the SARS-CoV-2 Omicron variant.

19 May 2022

In-depth characterization of the BA.2 versus BA.1 variant

In a recent study published in the journal Nature, researchers evaluated the pathogenicity and infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 variant in hamsters and mice.

19 May 2022

Standard blood cancer test holds clear clues of rare IgD multiple myeloma

A test for the common blood cancer multiple myeloma also holds clear clues that the patient has one of the most uncommon and deadly forms of this cancer, investigators say.

19 May 2022

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

Researchers predict structure models of the full-length SARS-CoV-2 N protein in both the presence and absence of RNA.

19 May 2022

Researchers combine two emerging imaging technologies to better view biomolecules

A research team from Carnegie Mellon University and Columbia have combined two emerging imaging technologies to better view a wide range of biomolecules, including proteins, lipids and DNA, at the nanoscale.

19 May 2022

How does diet affect COVID-19?

Scientists review the current research on how changes in diet can affect infection with SARS-CoV-2.

19 May 2022

Immunity conferred by COVID-19 vaccines in solid organ transplant recipients

In a recent study posted to the medRxiv* preprint server, researchers estimated the humoral immunity imparted by the two/three doses of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in solid organ transplant recipients (SOTRs).

18 May 2022

RGS2 protein expression may explain reduced sense of smell in COVID

Researchers tested the hypothesis that anosmia in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals elevates the expression of the odorant receptor, a regulator of G protein signaling 2 (RGS2) in humans.

18 May 2022

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

In a recent study posted to the bioRxiv* pre-print server, researchers from Belgium evaluated the efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antiviral drugs in a severe combined immunodeficient (SCID) mouse model.

18 May 2022

Protein C News and Research

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

New study reveals the genetic mechanism behind severe staphylococcal infections

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Researchers explore SARS-CoV-2 infection in lung myeloid cells

Scientists investigate relevance of COVID-19 vaccine-mediated T cell immunity to SARS-CoV-2 variants

New study helps to better understand re-infection rates and correlates of protection for SARS-CoV-2

Study finds Omicron variant is more stable than its ancestral strain on smooth and porous surfaces

Micro Products with Macro Impact; The Role of Microplate Readers in Life Sciences

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

Study investigates the detection of antibodies against SARS-CoV-2 in urine

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Study explores polyfunctionality of BNT162b2 COVID-19 vaccine-induced memory T-cells

In-depth characterization of the BA.2 versus BA.1 variant

Standard blood cancer test holds clear clues of rare IgD multiple myeloma

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

Researchers combine two emerging imaging technologies to better view biomolecules

How does diet affect COVID-19?

Immunity conferred by COVID-19 vaccines in solid organ transplant recipients

RGS2 protein expression may explain reduced sense of smell in COVID

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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