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Combination therapy improves response rates for chronic hepatitis B patients

The optimal management strategy for adults with immune-tolerant (IT) chronic hepatitis B infection remains undefined. This study aimed to investigate the efficacy and predictive factors of a pegylated interferon (Peg-IFN)-based treatment strategy in IT patients with chronic HBV infection.

22 May 2026

Scientists map genetic variants behind prostate cancer therapy failure

Recently, the research group led by Dr. Dechao Feng, Lecturer at University College London (UCL) and Distinguished Research Fellow at Zhejiang Provincial People's Hospital, published a review entitled "Intratumoral Androgens and Genetic Variants Driving Therapy Resistance in Prostate Cancer".

22 May 2026

Targeting a key protein reduces injury in steatotic liver transplantation

Steatotic donor livers are highly susceptible to post-transplant dysfunction; however, the underlying mechanisms remain incompletely understood.

22 May 2026

Scientists urge advocacy to protect vital global vaccine research

Scientists and physicians should advocate to protect the vaccine research infrastructure that has saved an estimated 154 million lives over the past 50 years, according to a new commentary by researchers at Weill Cornell Medicine and the University of Washington.

22 May 2026

Semaglutide helps patients who gain weight after bariatric surgery

New UCL research supports use of the weight loss drug semaglutide for patients who do not get enough benefit from bariatric surgery.

22 May 2026

Boston Children's scientists create new booster-free mRNA vaccine strategy

In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, extended the duration of the vaccine's protection in mice from a few months up to two years.

22 May 2026

Second-career nursing candidates help solve national staffing shortages

While the usual conversation about our national nursing shortage focuses on how to recruit young people, there is another potential pipeline: people in their 40s and 50s—often pursuing a second career—who are also, in many ways, exactly the nurses that NYU Langone Health needs.

22 May 2026

New study reveals nitric oxide’s widespread impact on genetics

Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome, the working portion of our DNA that helps make each person unique. Put simply, a single gene can be edited in different ways to produce multiple sets of instructions.

22 May 2026

New genetic roadmap offers targeted treatment for rare inflammatory disorder

Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.

22 May 2026

Oral drug improves platelet recovery during chemotherapy in gastrointestinal cancer patients

An oral medication already approved for thrombocytopenia in patients with liver disease significantly improved platelet recovery and helped patients with gastrointestinal cancers maintain platelet counts needed to continue chemotherapy as scheduled, according to results from a phase 2 clinical trial led by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, and Mass General Hospital.

21 May 2026

NHS cost to treat youth mental health crises quadruples over a decade

The annual cost to the NHS to treat children and young people experiencing a mental health crisis in specialised acute hospital wards in England quadrupled to £87.5 million between 2012 and 2022, finds a new study led by UCL researchers.

21 May 2026

New artificial intelligence model maps how genes work together inside cells

Scientists at the Icahn School of Medicine at Mount Sinai have created a new artificial intelligence (AI) model that helps reveal how genes function together inside human cells, offering a powerful new way to understand biology and disease.

21 May 2026

New computational tool uses plain language for genetic diagnosis

A new computational tool called MARRVEL-MCP helps researchers move toward genetic diagnoses more efficiently by analyzing and interpreting vast amounts of genetic and biological information using everyday language.

21 May 2026

New study shows how exercise hormone reduces multiple sclerosis symptoms

A new study offers clues as to why exercise can improve neurological symptoms in people with multiple sclerosis (MS).

21 May 2026

Uneven grey matter loss serves as a powerful new biomarker for early neurodegeneration

Universitat Oberta de Catalunya Alzheimer's disease begins to weave a web in the brain and remodel neuronal tissue 15 to 20 years before the first symptoms appear. From the time this happens, however, until the disease is diagnosed and, later, enters an advanced phase, it progresses along a continuum of changes to the brain.

21 May 2026

Elevated blood glucose during pregnancy signals a significantly higher future diabetic risk

Gestational diabetes is a strong risk factor for future type 2 diabetes, even in women with normal pre-pregnancy weight, according to a study at the University of Gothenburg. The researchers call for earlier testing and better follow-up.

21 May 2026

First-of-its-kind pregnancy hormone test reveals why female IBD patients face severe symptom flares

Inflammatory bowel disease (IBD), which comprises the inflammatory conditions Crohn's disease and ulcerative colitis, affects about 1.6 million Americans, many of whom cannot be effectively treated.

21 May 2026

New CA19-9 threshold improves pancreatic cancer risk prediction accuracy

A dual-threshold model for measuring the pancreatic tumor marker serum carbohydrate antigen 19-9 (CA19-9) identified patients with pancreatic cancer who had high-risk disease despite having low CA19-9 levels because of a genetic variation that impairs their ability to produce this biomarker.

21 May 2026

Study defines realistic performance goals for pediatric emergency departments

A large, multi-center study led by Ann & Robert H. Lurie Children's Hospital of Chicago derived "achievable benchmarks of care" (ABCs) using electronic health record data, which allows pediatric emergency departments across the country to set high yet realistic performance goals.

21 May 2026

Polymer-based immunotherapies enhance tumor targeting and immune activation

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

21 May 2026