Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

New study reveals twist in how intoxication happens

As New Year's Eve approaches, many people will experience the familiar buzz that comes from imbibing a favorite cocktail or glass of wine.

27 Dec 2018

Statins reduce the formation of brown adipose tissue

A certain proportion of the adult population has not only white adipose (or fatty) tissue, but also the brown kind. This brown adipose tissue helps to convert sugar and fat into heat. People with brown adipose tissue are better at regulating their body temperature in the winter, and are less likely to suffer from excess weight or diabetes.

21 Dec 2018

Study reveals urban and rural differences in prenatal exposure to essential and toxic elements

New findings from a team of Marshall University Joan C. Edwards School of Medicine researchers reveal urban and rural differences in prenatal exposure to essential and toxic elements.

13 Dec 2018

Failure of critical cellular energy sensor responsible for CKD progression, study finds

Chronic kidney disease, an affliction characterized by progressive loss of kidney function, affects millions of people worldwide and is associated with multi-organ damage, cardiovascular disease, and muscle wasting.

7 Dec 2018

Revolutionary dietary supplement aims to mitigate long term impact of alcohol consumption

Survivor is a revolutionary dietary supplement designed to boost your liver's response to alcohol, aimed at mitigating the negative impact it has on your body.

7 Dec 2018

Hazelnuts improve micronutrient levels in older adults

Older adults who added hazelnuts to their diet for a few months significantly improved their levels of two key micronutrients, new research at Oregon State University indicates.

6 Dec 2018

Researchers discover pathway for enhancing the self-repair efforts of injured kidneys

A team of researchers led by Jonathan Stamler, MD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, has discovered a pathway for enhancing the self-repair efforts of injured kidneys.

29 Nov 2018

Proton NMR spectroscopy shows hazelnuts from different regions have different metabolite profiles

Hazelnuts, like olive oil, cheese and other agricultural products, differ in flavor depending on their geographic origin.

29 Nov 2018

Sons of fathers who smoke have 51% lower sperm count

Studies have repeatedly linked maternal smoking during pregnancy with reduced sperm counts in male offspring. Now a research team at Lund University in Sweden has discovered that, independently of nicotine exposure from the mother, men whose fathers smoked at the time of pregnancy had half as many sperm as those with non-smoking fathers.

22 Nov 2018

Study evaluates second-hand marijuana smoke exposure among children

In a study designed to evaluate second-hand marijuana smoke exposure among children--a topic that scientists have not yet widely addressed--researchers at the Icahn School of Medicine at Mount Sinai found that nearly half of children whose parents smoked marijuana showed evidence of second-hand marijuana smoke exposure.

20 Nov 2018

Surprising discovery about BH4 may rekindle interest in once-promising pathway

In 2013, renowned Boston Children's Hospital pain researcher Clifford Woolf, MB, BCh, PhD, and chemist Kai Johnsson, PhD, his fellow co-founder at Quartet Medicine, believed they held the key to non-narcotic pain relief.

19 Nov 2018

Researchers find metabolite shuttle between cells in the liver that may combat tissue fibrosis

University of Minnesota Medical School researchers have made a discovery which could lead to a new way of thinking about how disease pathogenesis in the liver is regulated, which is important for understanding the condition nonalcoholic fatty liver disease, which is incredibly common and growing.

16 Nov 2018

Immunity connects gut microbiota and age-related pathologies

EPFL scientists have discovered how a dysfunction in the immune system can cause an overload of a gut bacterium. The bacterium produces excess lactic acid, which in turn triggers the production of reactive oxygen species that cause damage to cells and many age-related pathologies.

13 Nov 2018

Study uncovers link between gut disruption and aging

A new study has shed light on how the disruption of commensal bacteria within the gut can affect the immune system and lead to age-related pathologies.

13 Nov 2018

Scientists grow 3D, beating human heart tissue

Researchers at the University Medical Center Hamburg-Eppendorf have found a way to grow human heart tissue that can serve as a model for the atria of the heart.

8 Nov 2018

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

VTT and Dyadic International, Inc., today announced that VTT scientists will present the excellent results in their collaboration over the past two years at two international conferences: AAPS PharmSci on November 7th in Washington DC and PEGS Europe on November 14th in Lisbon.

5 Nov 2018

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

NeuroPointDX launches NPDX AA test to identify metabolic subtypes associated with autism

NeuroPointDX, a division of Stemina Biomarker Discovery, today announced the commercial launch of its NPDX AA test, which identifies metabolic subtypes associated with autism spectrum disorder.

1 Nov 2018

Study provides a new way of thinking about cold stress in plants

When temperatures drop, plants can't bundle up. Stuck outside, exposed, plants instead undergo a series of biochemical changes that protect cells from damage.

29 Oct 2018

Scientists find new way to predict obesity-related disease risk

Scientists at Scripps Research and collaborating corporate and academic partners have found a new way to use distinct molecular "signatures" from people with obesity to predict risk of developing diabetes and cardiovascular disease, an advance that could broaden the way doctors and scientists think about diagnosing and treating disease.

12 Oct 2018