Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Gene abnormality found to predict childhood leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

8 Jan 2009

Gene mutations found to predict acute lymphoblastic leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

7 Jan 2009

Virtuoso cell engineering

University of Michigan researchers have discovered that a key protein in cells plays a critical role in not one, but two processes affecting the development of cancer.

6 Jan 2009

MRI scans emerge as vital resource in treatment of back pain

Magnetic resonance imaging (MRI) is a growing technology providing an increasing number of clinical benefits when used in the evaluation of back pain according to an article in the January 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons.

5 Jan 2009

Laminin-111 shows potential for congenital muscular dystrophy

Current research suggests laminin, a protein that helps cells stick together, may lead to enhanced muscle repair in muscular dystrophy.

1 Jan 2009

Magnetic resonance imaging emerges as vital resource in back pain treatment

1 Jan 2009

Lung cancer cells activate inflammation to induce metastasis

A research team from the University of California, San Diego School of Medicine has identified a protein produced by cancerous lung epithelial cells that enhances metastasis by stimulating the activity of inflammatory cells.

1 Jan 2009

A rigorous method for liver biopsy

Liver biopsy is still considered the gold standard for grading, staging and "stad-ging" the chronic liver disease.

1 Jan 2009

Cardiovascular system proteins play a role in Alzheimer's

Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease.

22 Dec 2008

Patient-derived induced stem cells retain disease traits

The dying cells - the same type lost in patients with the devastating neurological disease spinal muscular atrophy - confirmed that the University of Wisconsin-Madison stem cell biologist had recreated the hallmarks of a genetic disorder in the lab, using stem cells derived from a patient.

22 Dec 2008

Multiple sclerosis drug natalizumab may reduce immunity

A drug used to treat multiple sclerosis might make some patients vulnerable to brain infection by reducing the number of immune cells there, researchers at UT Southwestern Medical Center have found.

16 Dec 2008

Alzheimer's researcher explores the variety of animal models now being used in research

Very few species spontaneously develop the cognitive, behavioral and neuropathological symptoms of Alzheimer's disease (AD), yet AD research must progress at a more rapid pace than the rate of human aging.

15 Dec 2008

Mechanism behind cardiac scarring discovered

In the aftermath of a heart attack, the body's own defenses may contribute to future heart failure. Authors of a new study believe they have identified a protein that plays an important role in a process that replaces dead heart muscle with stiffening scar tissue. The researchers are hopeful that the findings will lead to the development of new therapies to prevent this damage.

15 Dec 2008

Research aims to reduce scarring from heart attacks

A heart damaged by heart attack is usually broken, at least partially, for good.

14 Dec 2008

Cellular 'brakes' may slow memory process in aging brains

University of Florida researchers may have discovered why some brain cells necessary for healthy memory can survive old age or disease, while similar cells hardly a hairsbreadth away die.

10 Dec 2008

Aperio Technologies receives another patent for TDI arrays in microscope slide scanners

Aperio Technologies, Inc., (Aperio), a global leader in digital pathology for the healthcare and life sciences industry, announced today that the United States Patent and Trademark Office has issued the company patent No. 7,457,446 entitled "Fully Automatic Rapid Microscope Slide Scanner."

10 Dec 2008

Alternative splicing proteins prompt heart development

Just as the emotions it represents are dynamic, the heart's development requires dynamic shifts in proteins that prompt alternative spicing, a mechanism that allows a given gene to program the cell to make several proteins, said a group of researchers at Baylor College of Medicine in a report that appears online in the journal Proceedings of the National Academy of Sciences.

8 Dec 2008