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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

MicroRNAs linked to failure of duct development in mammary glands

Max Planck researchers discover novel mechanism for vertebrate organ development. Hormones, growth factors and several proteins ensure that development occurs in the right way, at the right time. The components that cause breast development in mammals, for example, were thought to be largely known. However, as a team of scientists from Göttingen, Frankfurt and Hanover have now discovered, in the case of breast development, hormones and proteins do not account for the full story.

10 Nov 2010

Contraceptive, antiviral gel using bee venom wins 2010 Gates Foundation grant

A vaginal gel that affords both contraception and HIV protection using nanoparticles that carry bee venom is one of the bold, unconventional ideas that won a 2010 Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation.

10 Nov 2010

Silence Therapeutics' Atu027 RNAi drug prevents pulmonary metastasis formation

Silence Therapeutics plc announces positive research findings demonstrating the ability of the Company's lead RNA interference (RNAi) drug candidate, Atu027, to prevent the formation of pulmonary metastasis in various animal models of cancer metastasis. Researchers showed that Atu027 inhibited multiple key biological processes that enable and contribute to the dissemination and formation of pulmonary metastases in a murine breast cancer metastasis model.

10 Nov 2010

NEW ANA testing does not diagnose disorder in 40% of scleroderma patients

New research from Georgetown University Medical Center (GUMC) suggests that up to 40 percent of scleroderma patients will not be correctly diagnosed with the disorder using a new automated commercial screening test. The findings of the study will be presented Wednesday, November 10th at the Annual Scientific Meeting of the American College of Rheumatology in Atlanta, Georgia.

9 Nov 2010

Blood 'metabolomics' study uncovers liver, heart, and kidney toxicity in healthy smokers

Examining the blood "metabolomics" profile of smokers immediately after they had a cigarette revealed activation of pathways involved in cell death, inflammation, and other forms of systemic damage, say researchers at Georgetown Lombardi Comprehensive Cancer Center, part of Georgetown University Medical Center.

9 Nov 2010

Abbott, CHAI enter agreement to provide HIV testing to infants

Abbott and the Clinton Health Access Initiative (CHAI) have joined forces to provide HIV testing to infants in all countries working in partnership with the CHAI. A key focus of this cooperation will be sub-Saharan Africa, which the World Health Organization estimates to account for 90 percent of global HIV infections in children.

9 Nov 2010

Research reveals EBV virus infected cell manipulates cancer-producing cells

A new discovery by UNC scientists describes how cells infected by the Epstein-Barr virus (EBV) produce small vesicles or sacs called exosomes, changing their cellular "cargo" of proteins and RNA. This altered exosome enters cells and can change the growth of recipient cells from benign to cancer-producing.

9 Nov 2010

New COLD-PCR technology to detect EGFR gene mutation

Transgenomic, Inc. today announced completion of a development study of several new assays to detect genetic mutations using the Company's proprietary Co-amplification at Lower Denaturing Temperature PCR (COLD-PCR) technology in the Epidermal Growth Factor Receptor (EGFR) gene.

8 Nov 2010

New findings could help scientists devise optimal therapies for Friedreich's ataxia

Scripps Research Institute scientists have taken a step closer to understanding the cause of Friedreich's ataxia, a debilitating neurological condition that affects tens of thousands of people worldwide, and so far has no cure.

8 Nov 2010

NCRI launches first virtual biobank for prostate cancer research

The first virtual biobank dedicated to prostate cancer research has been launched today by the National Cancer Research Institute (NCRI). The UK Prostate Cancer Sample Collection Database will house details of around 10,000 biological samples taken from men in the UK with and without prostate cancer.

8 Nov 2010

New benchtop robotic workstation simplifies next-generation sequencing workflows

IntegenX, Inc. today at the 60th Annual American Society of Human Genetics Meeting announced the launch of their Apollo 324 System, a benchtop robotic workstation that automates the construction of DNA fragment libraries for next-generation sequencing.

8 Nov 2010

Agilent announces solution for exon analysis based on SurePrint G3 Exon Microarrays

Agilent Technologies Inc. today announced a solution for exon analysis based on SurePrint G3 Exon Microarrays. The solution provides a major expansion of Agilent's portfolio of gene expression reagents, microarrays and bioinformatics systems. This new system, available in mid-November, enables researchers to examine alternately expressed exons according to recently updated content, providing a global picture of RNA expression.

4 Nov 2010

Regado receives funding under QTDP grant program to advance treatment for cardiovascular diseases

Regado Biosciences, Inc., a private biopharmaceutical company leading the development of antithrombotic aptamers with matched active control agents, announced today that it has received funding from the United States government under the Qualifying Therapeutic Discovery Project (QTDP) grants program to advance the development of the company's three programs, REG1, REG2 and REG3.

4 Nov 2010

BioCurex files patent for synthetic peptide in RECAF test

BioCurex, Inc. today announced that it has filed a new patent within the Patent Cooperation Treaty, which presently includes 142 countries.

4 Nov 2010

Regulus receives $488,989 grant under QTDP program

Regulus Therapeutics Inc. announced today that it has been awarded two grants totaling $488,989 under the Federal government's Qualifying Therapeutic Discovery Project Program.

4 Nov 2010

Alnylam third quarter revenue increases from $24.2 million to $27.7 million

Alnylam Pharmaceuticals, Inc. a leading RNAi therapeutics company, today reported its consolidated financial results for the third quarter ended September 30, 2010, and company highlights.

4 Nov 2010

Illumina launches TruSeq sample preparation, Exome Enrichment kits for sequencing studies

Illumina, Inc. today announced TruSeq sample preparation kits for DNA, RNA, and small RNA applications and the TruSeq Exome Enrichment Kit, for use across the company's portfolio of sequencing platforms.

From Illumina, Inc. 3 Nov 2010

Allen Institute releases new data and tools for exploring genes at work in human brain

The Allen Institute for Brain Science announced today its twentieth public data release, which includes new data and tools for exploring genes at work in the human brain. In addition to expanding and enhancing the Allen Human Brain Atlas, the Allen Institute launched two new human brain resources: the Ivy Glioblastoma Atlas Project and the NIMH Transcriptional Atlas of Human Brain Development.

3 Nov 2010

New Ovation systems improve nucleic acid extraction from FFPE tissue samples

NuGEN Technologies, the provider of innovative RNA and DNA sample preparation solutions for genomic analysis, today announced the availability of the Ovation WGA FFPE System and the Ovation RNA-Seq FFPE System. These are the first commercially available products designed specifically to enable researchers to utilize next-generation sequencing (NGS) technologies to analyze nucleic acids extracted from Formalin-Fixed Paraffin-Embedded (FFPE) tissues.

3 Nov 2010

Study suggests heredity may play a role in determining infant's susceptibility to AOP

A potentially life-threatening challenge characterized by pauses in breathing that can last for more than 20 seconds, apnea of prematurity (AOP) affects more than 50 percent of premature infants and is almost universal in the smallest of preemies. Caused in part by an underdeveloped central nervous system that can't adequately regulate breathing outside of the womb, especially during sleep, AOP is not yet fully understood by scientists and remains a grave concern among neonatologists and parents alike.

3 Nov 2010

RNA News and Research

Further Reading

MicroRNAs linked to failure of duct development in mammary glands

Contraceptive, antiviral gel using bee venom wins 2010 Gates Foundation grant

Silence Therapeutics' Atu027 RNAi drug prevents pulmonary metastasis formation

NEW ANA testing does not diagnose disorder in 40% of scleroderma patients

Blood 'metabolomics' study uncovers liver, heart, and kidney toxicity in healthy smokers

Abbott, CHAI enter agreement to provide HIV testing to infants

Research reveals EBV virus infected cell manipulates cancer-producing cells

New COLD-PCR technology to detect EGFR gene mutation

New findings could help scientists devise optimal therapies for Friedreich's ataxia

NCRI launches first virtual biobank for prostate cancer research

New benchtop robotic workstation simplifies next-generation sequencing workflows

Agilent announces solution for exon analysis based on SurePrint G3 Exon Microarrays

Regado receives funding under QTDP grant program to advance treatment for cardiovascular diseases

BioCurex files patent for synthetic peptide in RECAF test

Regulus receives $488,989 grant under QTDP program

Alnylam third quarter revenue increases from $24.2 million to $27.7 million

Illumina launches TruSeq sample preparation, Exome Enrichment kits for sequencing studies

Allen Institute releases new data and tools for exploring genes at work in human brain

New Ovation systems improve nucleic acid extraction from FFPE tissue samples

Study suggests heredity may play a role in determining infant's susceptibility to AOP

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