Efficacy News and Research

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An innovative treatment for joint pain

Tired of living with painful arthritic knees, 54-year-old Deborah Brown's interest was piqued when she saw a recruitment flyer for a clinical trial on an innovative pain treatment at The University of Texas Health Science Center at Houston (UTHealth).

18 Dec 2019

Catastrophic macropinocytosis may aid in cancer treatment

In laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route -- catastrophic macropinocytosis.

18 Dec 2019

Clinical study demonstrates effective alternative to mastectomy for recurrent breast cancer

Mastectomy has historically been the standard treatment for breast cancer patients experiencing recurrence after an initial lumpectomy and whole-breast radiation. Now, a phase 2 clinical trial led by Douglas W. Arthur, M.D., chair and professor in the Department of Radiation Oncology at VCU Massey Cancer Center and VCU School of Medicine, has demonstrated an effective alternative.

18 Dec 2019

Social and visual neural networks do not connect in some children with autism

Among the first and most-documented symptoms of autism spectrum disorder is a child's aversion to interaction with others. Specifically, they appear uninterested in social activities and stimuli that would normally attract a young child's attention, such as watching other children play, sing or dance.

17 Dec 2019

Pilot study shows strong results for genicular artery embolization to treat OA-related knee pain

A new study published in Journal of Vascular and Interventional Radiology details the first study of its kind in the U.S. to examine the use of genicular artery embolization (GAE) for extended treatment of knee pain caused by osteoarthritis.

17 Dec 2019

Zebrafish 'avatars' help distinguish radiosensitive from radioresistant tumors

Radiotherapy can effectively reduce or even eliminate some tumors; others, however, show enduring resistance. Considering the potentially harmful side effects of radiotherapy, clinicians agree that it is paramount to be able to determine if a patient will benefit from radiotherapy before exposing them to any of the associated risks.

17 Dec 2019

Antioxidant in green tea plant could be key to fighting tuberculosis

An antioxidant found in the green tea plant could become key to tackling tuberculosis one day, a team of international scientists led by Nanyang Technological University, Singapore has found.

17 Dec 2019

Study: Chemoradiation regimen for Stage III NSCLC is better than two tested alternatives

Lung cancer is the leading cause of cancer death in the United States and approximately 75-80% of all cases are non-small cell lung cancer (NSCLC).

17 Dec 2019

Novel drug from Amazon rainforest tree sap evaluated for treatment of chronic idiopathic diarrhea in non-HIV patients

A drug purified and developed from the sap of a tree in the Amazon rainforest is now being studied for the treatment of chronic idiopathic diarrhea in non-HIV patients at The University of Texas Health Science Center at Houston as part of a two-year pilot study.

16 Dec 2019

Immunotherapy: A promising new alternative to cancer therapies

Sophie Lucas, a researcher at the University of Louvain (UCLouvain) de Duve Institute, studies the immune responses that cancer patients can develop against their own tumor.

16 Dec 2019

New method of feeding tube insertion may offer improved patient safety, cost savings

A team of clinician researchers from Lawson Health Research Institute have partnered with medical device company CoapTech LLC to study a new method of feeding tube insertion.

16 Dec 2019

Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

Investigators at Rutgers Cancer Institute of New Jersey have found that a treatment based on a novel cellular product programmed to deliver an overabundance of chimeric antigen receptor causes cell death in non-Hodgkin lymphoma models that are sensitive or resistant to standard therapies.

16 Dec 2019

Novel drug shows efficacy against advanced ROS1 and NTRK fusion-positive NSCLC

Pooled analysis of three phase 1 and 2 clinical trials published online ahead of print in the journal Lancet Oncology show that the drug entrectinib is effective and well-tolerated against advanced ROS1 and NTRK fusion-positive non-small cell lung cancers (NSCLC).

14 Dec 2019

Gene drives are faster, more efficient to control mosquitoes that spread malaria

When controlling mosquitoes that spread malaria, gene drives, which force genetic changes to proliferate in a population, are faster and more efficient than simply releasing mosquitoes that are immune to the parasite, according to a new study published December 19th in PLOS Genetics by Anthony James at University of California, Irvine and colleagues.

13 Dec 2019

DigiM Solution receives FDA contract for microstructure imaging study

DigiM Solution LLC, a provider of microstructure characterization and optimization solutions and software, has received a contract from the Office of Generic Drugs of the U.S. Food and Drug Administration.

From DigiM Solution LLC 13 Dec 2019

Study finds African children are growing better because of America’s Feed the Future program

A new Stanford study published on December 11, 2019, in the BMJ, says that Feed the Future is indeed making an impact on over 2 million children in sub-Saharan Africa, who have been saved from experiencing malnutrition with its related issues. Feed the Future is a US governmental program that focuses on reducing global hunger and ensuring greater food security.

12 Dec 2019

Discovery of novel mechanism by which certain breast cancers can metastasize

Researchers from the Baylor College of Medicine and Harvard Medical School have found a novel mechanism to explain the resistance of certain breast cancers that spread in the major organs of the body. They hope that this would help develop new therapeutic strategies to treat the cancer.

12 Dec 2019

Vanda Pharmaceuticals' president wins award for effort to prevent and replace animal tests

President and CEO of Vanda Pharmaceuticals, Mihael H. Polymeropoulos, MD, is the inaugural recipient of The Trailblazer Award, given by the Physicians Committee--a nonprofit with more than 12,000 doctor members--for his unwavering commitment to prevent and replace animal tests and advance more human-relevant science.

12 Dec 2019

Single, higher dose of Zika vaccine to pregnant female mice protects both mom and fetus

Researchers from The University of Texas Medical Branch at Galveston showed, for the first time, that a single, higher dose of vaccination to a pregnant mouse safely protects both her and her fetus from the Zika virus.

12 Dec 2019

New book provides extensive research into health effects of football

The new book "Football as Medicine - Prescribing Football for Global Health Promotion" collates 15 years of research when describing the effects of football training on cardiovascular, metabolic and musculoskeletal fitness, and providing up-to-date knowledge of the impact of recreational football for target populations like children, type 2 diabetes patients, cancer patients, people with mental health conditions, the socially deprived and older people.

12 Dec 2019

Efficacy News and Research

An innovative treatment for joint pain

Catastrophic macropinocytosis may aid in cancer treatment

Clinical study demonstrates effective alternative to mastectomy for recurrent breast cancer

Social and visual neural networks do not connect in some children with autism

Pilot study shows strong results for genicular artery embolization to treat OA-related knee pain

Zebrafish 'avatars' help distinguish radiosensitive from radioresistant tumors

Antioxidant in green tea plant could be key to fighting tuberculosis

Study: Chemoradiation regimen for Stage III NSCLC is better than two tested alternatives

Novel drug from Amazon rainforest tree sap evaluated for treatment of chronic idiopathic diarrhea in non-HIV patients

Immunotherapy: A promising new alternative to cancer therapies

New method of feeding tube insertion may offer improved patient safety, cost savings

Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

Novel drug shows efficacy against advanced ROS1 and NTRK fusion-positive NSCLC

Gene drives are faster, more efficient to control mosquitoes that spread malaria

DigiM Solution receives FDA contract for microstructure imaging study

Study finds African children are growing better because of America’s Feed the Future program

Discovery of novel mechanism by which certain breast cancers can metastasize

Vanda Pharmaceuticals' president wins award for effort to prevent and replace animal tests

Single, higher dose of Zika vaccine to pregnant female mice protects both mom and fetus

New book provides extensive research into health effects of football

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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