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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Pushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular machines, as it locks onto DNA and loads the machinery for reading the genetic code.

20 Nov 2018

About 300 million bits of DNA are missing from basic reference genome, report scientists

For the past 17 years, most scientists around the globe have been using the nucleic acid sequence, or genome, an assembly of DNA information, from primarily a single individual as a kind of "baseline" reference and human species representation for comparing genetic variety among groups of people.

20 Nov 2018

Researchers identify genetic changes that could increase risk for death by suicide

Researchers at University of Utah Health identified four gene changes that occur more frequently in people who died by suicide that may point to increased risk in vulnerable individuals.

19 Nov 2018

New report highlights key focus areas to help cancer screening realize its full potential

Cancer screening has contributed substantially to reduced incidence, morbidity, and mortality, but issues like access and quality care and have kept screening from fulfilling its full potential, according to a new report.

19 Nov 2018

2PG Company receives grant to develop sensitive, low-cost molecular diagnostic tests for tuberculosis

Two Pore Guys, Inc. today announced that the company has received a $2.8 million grant from the Bill & Melinda Gates Foundation to develop sensitive, low-cost molecular diagnostic tests for tuberculosis using its solid-state nanopore technology.

19 Nov 2018

Molecular DNA analysis could facilitate more accurate prognosis, treatment of aggressive brain tumors

Meningiomas, a type of brain tumor, are usually easy to treat. However, there are a few subtypes that follow a very aggressive course and have high recurrence rates, i.e. there is a high risk of them coming back after treatment.

19 Nov 2018

Insilico Medicine to introduce 'Cure a disease in a year' program at Biodata World Congress 2018

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery and real world evidence pipeline utilizing the next generation artificial intelligence, will present its research and introduce the "Cure a disease in a year" program at the World's leading congress for big data in precision medicine - Biodata World Congress 2018.

19 Nov 2018

Scientists discover new inhibitor that decreases lung inflammation

Scientists from the University of Sheffield have discovered a new inhibitor which decreases lung inflammation and could hold the key to treating Acute Respiratory Distress Syndrome - a life-threatening disease which affects thousands of people in the UK.

18 Nov 2018

New strategy to hinder emergence of antimicrobial-resistant pathogens

With many disease-causing bacteria ratcheting up their shields against current drugs, new tactics are vital to protect people from treatment-resistant infections.

17 Nov 2018

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

A majority of the HIV-infected cells that persist in HIV-infected individuals even during suppressive antiretroviral therapy originated from cellular proliferation, not viral replication, according to new research published in Nature Communications.

17 Nov 2018

UCLA biologists uncover how head injuries can lead to serious brain disorders

UCLA biologists have discovered how head injuries adversely affect individual cells and genes that can lead to serious brain disorders.

17 Nov 2018

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalized treatment in the future.

16 Nov 2018

Research team identifies Ashkenazi Jewish founder mutation for Leigh syndrome

Over 30 years ago, Marsha and Allen Barnett lost their sons to a puzzling childhood disease that relentlessly attacked their nervous systems and sapped their energy.

15 Nov 2018

Researchers develop new drug molecule that inhibits inflammation

A multidisciplinary team of researchers led from Karolinska Institutet in Sweden have developed an anti-inflammatory drug molecule with a new mechanism of action.

15 Nov 2018

Non-coding genetic variant plays key role in endothelial function and disease incidence

Atherosclerotic disease, the slow and silent hardening and narrowing of the arteries, is a leading cause of mortality worldwide. It is responsible for more than 15 million deaths each year, including an estimated 610,000 people in the United States.

15 Nov 2018

Luxia Scientific announces availability of its gut microbiome test in Luxembourg

Luxia Scientific, a French biotech dedicated to improving well-being and health for all through the analysis and understanding of the microbiome, announces the availability of its test “1test1” in Luxembourg. The test was launched in France beginning of October 2018.

15 Nov 2018

Researchers directly connect activities of genes with instinctive behavior in male cichlids

Call it instinct, but something compels some animals to behave in certain ways, perhaps programs in their genes. Researchers have directly connected activities of genes with instinctive behavior in little male fish that make patterns in the sand to attract their mates.

15 Nov 2018

Human Cell Atlas study of early pregnancy shows how mother's immune system is modified

The first Human Cell Atlas study of early pregnancy in humans has shown how the function of the maternal immune system is affected by cells from the developing placenta.

14 Nov 2018

Speed and error rate of DNA synthesis influenced by DNA structure

The speed and error rate of DNA synthesis is influenced by the three-dimensional structure of the DNA. Using "third-generation" genome-wide DNA sequencing data, a team of researchers from Penn State and the Czech Academy of Sciences showed that sequences with the potential to form unusual DNA conformations, which are frequently associated with cancer and neurological diseases, can in fact slow down or speed up the DNA synthesis process and cause more or fewer sequencing errors.

14 Nov 2018

Study defines biomarker in response to treatment of castration-resistant prostate cancer

The most aggressive type of prostate cancer, castration-resistant prostate cancer, can be treated with two different therapies: taxanes or hormone treatment. Until this day there are no comparative studies between the two and the decision on which treatment to use is done empirically and based on the patient's preferences.

14 Nov 2018

DNA News and Research

Further Reading

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

About 300 million bits of DNA are missing from basic reference genome, report scientists

Researchers identify genetic changes that could increase risk for death by suicide

New report highlights key focus areas to help cancer screening realize its full potential

2PG Company receives grant to develop sensitive, low-cost molecular diagnostic tests for tuberculosis

Molecular DNA analysis could facilitate more accurate prognosis, treatment of aggressive brain tumors

Insilico Medicine to introduce 'Cure a disease in a year' program at Biodata World Congress 2018

Scientists discover new inhibitor that decreases lung inflammation

New strategy to hinder emergence of antimicrobial-resistant pathogens

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

UCLA biologists uncover how head injuries can lead to serious brain disorders

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

Research team identifies Ashkenazi Jewish founder mutation for Leigh syndrome

Researchers develop new drug molecule that inhibits inflammation

Non-coding genetic variant plays key role in endothelial function and disease incidence

Luxia Scientific announces availability of its gut microbiome test in Luxembourg

Researchers directly connect activities of genes with instinctive behavior in male cichlids

Human Cell Atlas study of early pregnancy shows how mother's immune system is modified

Speed and error rate of DNA synthesis influenced by DNA structure

Study defines biomarker in response to treatment of castration-resistant prostate cancer

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