Antibodies News and Research

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New trial shows felzartamab reduces proteinuria in IgA nephropathy patients

IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their surface.

26 Oct 2024

Climate change impacts pollen patterns and allergy sensitization in Chicago

People have heard for years that climate change is having a significant impact on plant vegetation patterns and influencing how pollen and mold produce.

25 Oct 2024

Exclusive: Emails reveal how health departments struggle to track human cases of bird flu

Bird flu cases have more than doubled in the country within a few weeks, but researchers can't determine why the spike is happening because surveillance for human infections has been patchy for seven months.

25 Oct 2024

Researchers develop first-of-its-kind therapy to enhance heart repair after a heart attack

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind experimental therapy that has the potential to enhance heart repair following a heart attack, preventing the onset of heart failure.

24 Oct 2024

Repeated mRNA vaccinations enhance mucosal antibody production

During the COVID pandemic, many of us have received multiple mRNA vaccines. New work by researchers at the VIB-UGent Center for Inflammation Research, Ghent University, and University Hospital Ghent, among others, has found that such repeated vaccinations lead to the presence of mucosal antibodies, for example, inside the nose. Their work appears in Science Translational Medicine.

23 Oct 2024

New antibody platform targets evolving viruses

Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.

23 Oct 2024

Immunotherapy may be an effective treatment strategy for heart failure

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy - similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis - also may be an effective treatment strategy for heart failure.

23 Oct 2024

Maternal antibodies may hinder malaria vaccine effectiveness in infants

Maternal antibodies passed across the placenta can interfere with the response to the malaria vaccine, which would explain its lower efficacy in infants under five months of age, according to research led by the Barcelona Institute for Global Health (ISGlobal), in collaboration with seven African centers (CISM-Mozambique, IHI-Tanzania, CRUN-Burkina Faso, KHRC-Ghana, NNIMR-Ghana, CERMEL-Gabon, KEMRI-Kenya).

23 Oct 2024

Calluna Pharma successfully completes Phase 1 clinical study of CAL101, a first-in-class therapeutic for fibrotic and fibro-inflammatory indications

Calluna Pharma AS (Calluna), a clinical stage biotechnology company pioneering first-in-class antibodies to treat inflammatory and fibrotic diseases, today announced the completion of Phase 1 clinical study for CAL101, Calluna’s lead product candidate.

23 Oct 2024

Advancements in antibody-drug conjugates transform cancer therapy

Antibody-drug conjugates (ADCs) have emerged as a promising approach in cancer therapy, offering a 'magic bullet' strategy that combines the precision of monoclonal antibodies with the potency of cytotoxic drugs.

22 Oct 2024

UK-DTOP tool promises improved outcomes for kidney transplant recipients

A new advanced artificial intelligence (AI) tool, developed by renal doctors internationally, represents a significant step forward in predicting and potentially improving outcomes for UK kidney transplant patients.

22 Oct 2024

New antibody targets cancer-causing HER2 mutations

For some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and causing cancer.

22 Oct 2024

New single-chain mRNA vaccines offer enhanced immunity and protection against mpox

Study reveals single-chain mRNA vaccines confer 100% protection against lethal mpox challenge in mice, marking a significant advancement in vaccine technology.

22 Oct 2024

Novel antibodies show promise for tumor targeting and RAD51 inhibition

A new research paper was published in Oncotarget's Volume 15 on October 1, 2024, entitled, "Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition."

21 Oct 2024

Emory researchers discover enzyme to combat IgG-mediated disorders

Myasthenia gravis (MG) is a chronic autoimmune disorder in which antibodies block communication between nerves and muscle, resulting in weakness of the skeletal muscles.

21 Oct 2024

Sapio Sciences enhances lab informatics platform with new immunogenicity bioanalysis features

Sapio Sciences, the science-aware™ lab informatics platform, today announced the addition of new immunogenicity bioanalysis features to its industry-leading lab informatics platform.

18 Oct 2024

Trial evaluates monoclonal antibodies for long COVID prevention

The first randomized, placebo-controlled clinical trial evaluating the impact of therapeutic monoclonal antibodies on the risk of developing long COVID was led by researchers at Weill Cornell Medicine.

17 Oct 2024

Gum disease tied to higher thrombosis risk: Could periodontal therapy help save lives?

The connection between gum disease and thrombosis underscores the role of oral health in reducing thrombotic disease risk and improving patient outcomes.

17 Oct 2024

A deeper look at COVID-19 transmission and fetal health

A new Cleveland Clinic-led study published in The EMBO Journal shows that mild and asymptomatic SARS-CoV-2 infections can trigger immune responses in a pregnant individual that may cause serious inflammatory responses in the developing fetus.

17 Oct 2024

New handheld device promises rapid blood diagnostics

Patients who go to the doctor to provide a blood sample are typically faced with a needle and syringe and hours or days of waiting to get results back from a lab.

16 Oct 2024

Antibodies News and Research

New trial shows felzartamab reduces proteinuria in IgA nephropathy patients

Climate change impacts pollen patterns and allergy sensitization in Chicago

Exclusive: Emails reveal how health departments struggle to track human cases of bird flu

Researchers develop first-of-its-kind therapy to enhance heart repair after a heart attack

Repeated mRNA vaccinations enhance mucosal antibody production

New antibody platform targets evolving viruses

Immunotherapy may be an effective treatment strategy for heart failure

Maternal antibodies may hinder malaria vaccine effectiveness in infants

Calluna Pharma successfully completes Phase 1 clinical study of CAL101, a first-in-class therapeutic for fibrotic and fibro-inflammatory indications

Advancements in antibody-drug conjugates transform cancer therapy

UK-DTOP tool promises improved outcomes for kidney transplant recipients

New antibody targets cancer-causing HER2 mutations

New single-chain mRNA vaccines offer enhanced immunity and protection against mpox

Novel antibodies show promise for tumor targeting and RAD51 inhibition

Emory researchers discover enzyme to combat IgG-mediated disorders

Sapio Sciences enhances lab informatics platform with new immunogenicity bioanalysis features

Trial evaluates monoclonal antibodies for long COVID prevention

Gum disease tied to higher thrombosis risk: Could periodontal therapy help save lives?

A deeper look at COVID-19 transmission and fetal health

New handheld device promises rapid blood diagnostics

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