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Brain estrogen critical for astrocyte activation and neuroprotection

When the brain isn't getting enough oxygen, estrogen produced by neurons in both males and females hyperactivates another brain cell type called astrocytes to step up their usual support and protect brain function.

1 Sep 2020

New approach to combination drug design could be applied to disease therapies beyond diabetes

Biomedical engineers at Duke University have shown that the efficacy of a two-pronged type 2 diabetes treatment increases when the drugs are linked by a heat-sensitive tether rather than simply concurrently administered.

27 Aug 2020

Exosomes: The cancer cell communication mechanism

Professor Deborah Goberdhan speaks to News-Medical about her team's latest research into cancer cells, and the mechanisms they use to communicate.

26 Aug 2020

Researchers document comprehensive communication pathways in human cell infected with SARS-CoV-2

In the transmission of signals within the cell which, for example, stimulate cell growth or trigger metabolic processes, phosphate groups play an important biochemical role.

25 Aug 2020

Women with T1a breast cancers could benefit from hormone treatment

Many people diagnosed with breast cancers that are small but invasive could benefit from hormone treatment, a new study led by physicians at Roswell Park Comprehensive Cancer Center confirms. Their findings were published today in the journal JAMA Network Open.

24 Aug 2020

RNA-targeting compound restarts a healing factor silenced by heart attack

A heart attack can leave parts of the heart permanently scarred and stiff, resulting in prolonged disability and potential progression toward heart failure. Scientists have studied various ways to repair or regenerate such damaged heart tissue, with limited success.

24 Aug 2020

Researchers find clues to successful immune response in the T cells of COVID-19 patients

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

21 Aug 2020

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

A new federally funded study could reveal the nervous system cells and circuits in our brains that influence our metabolism and health in response to dietary changes.

21 Aug 2020

New insights into how high-protein diet protects against fatty liver

Non-alcoholic fatty liver disease is the most common chronic liver disease in the world, with sometimes life-threatening consequences.

18 Aug 2020

Cyborg technology: Researchers take new step toward integrating electronics with the body

Although true "cyborgs" - part human, part robotic beings - are science fiction, researchers are taking steps toward integrating electronics with the body.

17 Aug 2020

Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

NIBIB-funded researchers have created nanoparticles for successful gene therapy of a mouse model of macular degeneration.

15 Aug 2020

Researchers review scientific articles on proteins that help cancer cells enter the brain

An international team of scientists, including a researcher from Sechenov University, reviewed scientific articles on proteins (and genes encoding them) that help cancer cells enter the brain.

12 Aug 2020

Researchers identify new treatment for osteoarthritis

The study results revolve around the long-established idea that machines within animal and human cells turn the sugars, fats, and proteins we eat into energy used by the body's millions of cells.

10 Aug 2020

Scientists identify new treatment targets for blinding retinal disease

When the eye isn't getting enough oxygen in the face of common conditions like premature birth or diabetes, it sets in motion a state of frenzied energy production that can ultimately result in blindness, and now scientists have identified new points where they may be able to calm the frenzy and instead enable recovery

10 Aug 2020

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

As COVID-19 continues to take a heavy toll on human health and life in many parts of the world, there is still no effective antiviral drug or vaccine. This has fueled an intensive search for small molecules and proteins that can inhibit viral entry and replication.

10 Aug 2020

FDA approves first companion diagnostic that uses liquid biopsy and NGS technology

Today, the U.S. Food and Drug Administration approved the first liquid biopsy companion diagnostic that also uses next-generation sequencing (NGS) technology to identify patients with specific types of mutations of the epidermal growth factor receptor (EGFR) gene in a deadly form of metastatic non-small cell lung cancer (NSCLC).

7 Aug 2020

Researchers establish new 3D in vitro model for pulmonary arterial hypertension

Pulmonary arterial hypertension is a rare--albeit deadly--disease that affects the arteries of the lung. In PAH, abnormal growth of cells of the vascular media--or the elastic wall--of the pulmonary arteries, called pulmonary arterial smooth muscle cells, results in thickening of the walls.

7 Aug 2020

New type of immunotherapy shows promise for advanced skin cancer

A new type of immunotherapy for the skin cancer malignant melanoma shows promising results. Three severely ill patients are now long-term survivors.

7 Aug 2020

New peptide molecule offers hope for emphysema

Emphysema is a progressive, debilitating lung disease in which the lung's breathing sacs, or alveoli, enlarge, get thinner, and eventually are destroyed as the cells die off. It can be fatal, and there is currently no cure.

4 Aug 2020

Reducing the incidence of drug-induced interstitial lung disease in breast cancer patients

Announcing a new article publication for BIO Integration journal. In this case report the authors Zijun Zhao, Zhanghai He, Hongyan Huang, Jiewen Chen, Shishi He, Ailifeire Yilihamu and Yan Nie from Sun Yat-sen University, Guangzhou, China consider drug-induced interstitial lung disease in breast cancer patients.

27 Jul 2020

Growth Factor News and Research

Brain estrogen critical for astrocyte activation and neuroprotection

New approach to combination drug design could be applied to disease therapies beyond diabetes

Exosomes: The cancer cell communication mechanism

Researchers document comprehensive communication pathways in human cell infected with SARS-CoV-2

Women with T1a breast cancers could benefit from hormone treatment

RNA-targeting compound restarts a healing factor silenced by heart attack

Researchers find clues to successful immune response in the T cells of COVID-19 patients

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

New insights into how high-protein diet protects against fatty liver

Cyborg technology: Researchers take new step toward integrating electronics with the body

Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

Researchers review scientific articles on proteins that help cancer cells enter the brain

Researchers identify new treatment for osteoarthritis

Scientists identify new treatment targets for blinding retinal disease

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

FDA approves first companion diagnostic that uses liquid biopsy and NGS technology

Researchers establish new 3D in vitro model for pulmonary arterial hypertension

New type of immunotherapy shows promise for advanced skin cancer

New peptide molecule offers hope for emphysema

Reducing the incidence of drug-induced interstitial lung disease in breast cancer patients

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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