Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

New peptides improve memory in mice with Alzheimer’s

Alzheimer’s disease (AD) affects over 44 million people the world over. But now, neurologist Jack Jhamandas and his team have found two short peptides which, on daily injection into mice with symptoms of AD for just five weeks, led to a significant improvement.

18 Sep 2019

Exercise may delay brain deterioration in people at high risk for Alzheimer's

Exercising several times a week may delay brain deterioration in people at high risk for Alzheimer's disease, according to a study that scientists say merits further research to establish whether fitness can affect the progression of dementia.

18 Sep 2019

Foods rich in LH dipeptide may help maintain good mental health

A research group led by Professor Tomoyuki Furuyashiki and Associate Professor Shiho Kitaoka (Graduate School of Medicine) in collaboration with researcher Yasuhisa Ano of Kirin Holdings have made discoveries regarding the effect of the dipeptide Leucine-Histidine in suppressing microglial activation and depression-associated emotional disturbances.

13 Sep 2019

Research reveals new molecular mechanisms that contribute to plasticity of the adult brain

The team's findings describe for the first time the changes that take place in the genetic material of excitatory neurons in the hippocampus of adult mice when they activate.

12 Sep 2019

Researchers identify mechanism responsible for spatial issues in people with Down syndrome

Researchers reveal that an imbalance of gene Grik1 is behind the spatial issues that people with Down syndrome experience.

11 Sep 2019

Move better, think faster - A fitter body sharpens the mind

A large German study that has just been presented at the Copenhagen ECNP Congress shows that in young adults, the fitter you are, the better your brain works and is organized, too. This could possibly mean that helping people with impaired thinking and memory to become fit could help boost their cognitive functioning. It could also help enhance brain structure.

10 Sep 2019

Researchers investigate how to prevent the onset of schizophrenia using mouse model

Although predisposing processes occur earlier, schizophrenia breaks out at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals.

9 Sep 2019

Resistance to 'hunger hormone' linked with cognitive impairments and memory loss

Scientists at The University of Texas at Dallas have found evidence suggesting that resistance to the "hunger hormone" ghrelin in the brain is linked to the cognitive impairments and memory loss associated with Alzheimer's disease.

4 Sep 2019

Neurogenesis plays an underappreciated role in the progression of Alzheimer's

Much of the research on the underlying causes of Alzheimer's disease focuses on amyloid beta (Aß), a protein that accumulates in the brain as the disease progresses.

30 Aug 2019

Study findings raise new concerns about vulnerability of preterm brain to hypoxia

Nearly 15 million babies are born prematurely, or before 37 weeks of pregnancy, around the world each year. When born too early, a baby's immature respiratory center in the brain often fails to signal it to breathe, resulting in low oxygen levels, or hypoxia, in the brain.

29 Aug 2019

Researchers find protective factor against Alzheimer’s disease

Researchers at the German Center for Neurodegenerative Diseases and the Institute for Stroke and Dementia Research at the University Hospital of the Ludwig-Maximilians-Universität in Munich have found that a protein called TREM2 could positively influence the course of Alzheimer's disease.

29 Aug 2019

Hyperactive signaling pathway blocks cell division in the aging brain

Scientists from Basel have investigated the activity of stem cells in the brain of mice and discovered a key mechanism that controls cell proliferation.

29 Aug 2019

Single bout of exercise may provide a boost to the aging brain

Exercise seems to endow a wealth of benefits, from the release of happiness-inducing hormones to higher physical fitness. New research shows it may provide a boost to the mind too.

26 Aug 2019

Strong memories formed by "teams" of neurons firing in synchrony

Almost everyone knows how it feels to remember things for decades on end – and also how it feels to forget where you left your car keys. The answer to this strange paradox could be simple, according to a new study from Caltech. The researchers found that that the brain recruits a higher number of neurons which fire impulses in a synchronized manner to form and store strong memories over long periods.

26 Aug 2019

Caltech researchers determine how memories form and fade

Why is it that you can remember the name of your childhood best friend that you haven't seen in years yet easily forget the name of a person you just met a moment ago? In other words, why are some memories stable over decades, while others fade within minutes?

25 Aug 2019

Alzheimer's drug reverses brain damage in rats exposed to alcohol during adolescence

A drug used to slow cognitive decline in adults with Alzheimer's disease appears to reverse brain inflammation and neuron damage in rats exposed to alcohol during adolescence.

20 Aug 2019

Umea researchers' model reveals why memory deteriorates as the body ages

Researchers in Umeå, Sweden, have presented a model that explains why memory deteriorates as the body ages. With age, the brain receives an increased load from the heart's beating as the body's large arteries stiffen over the years, causing damage to the smallest blood vessels in the brain.

20 Aug 2019

Traumatic childhood experiences change perception of social stimuli in adulthood

People with maltreatment experiences in their childhood have a changed perception of social stimuli later as adults. This is what scientists from the Division of Medical Psychology at the University of Bonn have discovered.

19 Aug 2019

New research reveals how our brain remembers the order of events

For centuries understanding how the order of events is stored in memory has been a mystery. However, researchers from the Department of Computer Science at the University of Warwick have worked out how the order of events in memory could be stored and later recalled in the hippocampal memory system in the brain.

14 Aug 2019

Negative memory hippocampal engrams could underlie cognitive symptoms of depression

Physical manifestations of negative memories in the hippocampus could underlie cognitive symptoms of depression, according to research in mice published in JNeurosci. Inhibiting these manifestations could be a future treatment route.

From Society for Neuroscience 13 Aug 2019

Hippocampus News and Research

Further Reading

New peptides improve memory in mice with Alzheimer’s

Exercise may delay brain deterioration in people at high risk for Alzheimer's

Foods rich in LH dipeptide may help maintain good mental health

Research reveals new molecular mechanisms that contribute to plasticity of the adult brain

Researchers identify mechanism responsible for spatial issues in people with Down syndrome

Move better, think faster - A fitter body sharpens the mind

Researchers investigate how to prevent the onset of schizophrenia using mouse model

Resistance to 'hunger hormone' linked with cognitive impairments and memory loss

Neurogenesis plays an underappreciated role in the progression of Alzheimer's

Study findings raise new concerns about vulnerability of preterm brain to hypoxia

Researchers find protective factor against Alzheimer’s disease

Hyperactive signaling pathway blocks cell division in the aging brain

Single bout of exercise may provide a boost to the aging brain

Strong memories formed by "teams" of neurons firing in synchrony

Caltech researchers determine how memories form and fade

Alzheimer's drug reverses brain damage in rats exposed to alcohol during adolescence

Umea researchers' model reveals why memory deteriorates as the body ages

Traumatic childhood experiences change perception of social stimuli in adulthood

New research reveals how our brain remembers the order of events

Negative memory hippocampal engrams could underlie cognitive symptoms of depression

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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