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COPD: Ion channels in immune cells could potentially be targets for new therapies

Chronic obstructive pulmonary disease – COPD for short – is one of the most common diseases of the lung. It affects almost 300 million people worldwide, of which about three million die every year.

17 Jan 2022

Discovery opens up the possibility of pursuing new therapies for FOP

Fibrodysplasia ossificans progressiva (FOP) is a rare disease characterized by extensive bone growth outside of the normal skeleton that pre-empts the body's normal responses to even minor injuries. It results in what some term a "second skeleton," which locks up joint movement and could make it hard to breathe.

16 Jan 2022

Mutations in SARS-CoV-2 Omicron variant promote cell binding

Researchers in Germany, based on their recent study published in the journal ChemBioChem, have proposed that the elevated occurrence of positively charged amino acids in specific domains of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) Omicron variant spike protein improves viral binding to cellular negatively charged receptors aiding in enhanced infectiousness.

16 Jan 2022

Cannabidiol may improve innate immune response against SARS-CoV-2

A recent study shows evidence that cannabidiol, an important active ingredient in the Cannabis sativa plant, can augment the antiviral innate immune response and prophylactically prime the innate antiviral response of cells – enabling in turn improved response against viruses such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Jan 2022

Study provides valuable insight into the developmental origins of schizophrenia

Scientists from Cardiff University have discovered new links between the breakdown in brain cell development and the risk of schizophrenia and other psychiatric disorders.

16 Jan 2022

Rapid antigen test for SARS-CoV-2 proves to be highly accurate for pediatric populations

In a large prospective study of just over 1,000 patients ages 17 and younger who were seen at the Baltimore Convention Center Field Hospital (BCCFH) testing site during a seven-month period last year, researchers from Johns Hopkins Medicine and collaborating institutions report that a rapid antigen test for SARS-CoV-2 — the virus that causes COVID-19 — proved highly accurate when compared to the established standard virus detection method: the polymerase chain reaction (PCR).

16 Jan 2022

Research could advance the understanding of links between heart disease and dementia

Heart disease can directly cause brain dysfunction early on which could lead to dementia and can treble the amount of an Alzheimer's protein in the brain, say scientists.

13 Jan 2022

Researchers implement and evaluate an educational intervention for prostate cancer

Prostate cancer is the second deadliest cancer in men in the United States. The incidence of prostate cancer in Black men is nearly 60% greater than the incidence in white men.

13 Jan 2022

Virus-like particles as delivery vehicles for gene-editing

Scientists deliver gene-editing proteins through the use of engineered virus-like particles, which mediated efficient base editing both in vitro and in vivo.

13 Jan 2022

Researchers identify gene variant that protects against severe COVID-19

An international metastudy led by researchers at Karolinska Institutet in Sweden has identified a specific gene variant that protects against severe COVID-19 infection.

13 Jan 2022

New project aims to study how bacterial defenses influence the spread of mobile genetic elements

A major new project will investigate how bacterial defenses influence the spread of segments of DNA called mobile genetic elements (MGEs) between bacteria.

13 Jan 2022

Investigating the presence of human rRNA in the SARS-CoV-2 genome

In a new study, a team of researchers investigated the existence of SARS-CoV-2-host chimeric RNA and described two novel human-derived genomic insertions present in the circulating variants of SARS-CoV-2.

13 Jan 2022

Defective gene in blood cancers could be treated with already available drugs

A defective gene, normally found in blood cancers, could be treated with drugs already available for cancers with similar gene defects, scientists at Queen’s University Belfast and the University of Birmingham have revealed.

13 Jan 2022

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours - a feat that's nearly unheard of in standard clinical care.

13 Jan 2022

The zoonotic potential of epidemic porcine deltacoronavirus

The present state of knowledge about the genesis, evolution, cross-species transmission, and zoonotic potential of PDCoV is the subject of a review published in the journal Pathogens, which was conducted in a combined effort by researchers from Heilongjiang Bayi Agricultural University and Ohio State University.

13 Jan 2022

Overall survival rate has nearly doubled for Ph+ ALL patients after hematopoietic stem cell transplant

For patients with acute lymphoblastic leukemia (ALL) carrying the Philadelphia chromosome and whose disease relapsed after allogeneic hematopoietic stem cell transplantation (HCT), the two-year overall survival rate has nearly doubled from the period between 2000 and 2004 to the period between 2015 and 2019.

13 Jan 2022

Metabolic vulnerabilities in malignant cells may lead to new breast cancer therapies

Metabolic differences could explain why some metastatic breast cancer cells rapidly generate tumors after migrating from primary tumors to the brain, while others linger for months or years before forming these secondary tumors, UT Southwestern scientists report in a new study.

12 Jan 2022

Genetic News and Research

COPD: Ion channels in immune cells could potentially be targets for new therapies

Discovery opens up the possibility of pursuing new therapies for FOP

Mutations in SARS-CoV-2 Omicron variant promote cell binding

Cannabidiol may improve innate immune response against SARS-CoV-2

Study provides valuable insight into the developmental origins of schizophrenia

Rapid antigen test for SARS-CoV-2 proves to be highly accurate for pediatric populations

Research could advance the understanding of links between heart disease and dementia

Researchers implement and evaluate an educational intervention for prostate cancer

Virus-like particles as delivery vehicles for gene-editing

Researchers identify gene variant that protects against severe COVID-19

New project aims to study how bacterial defenses influence the spread of mobile genetic elements

Investigating the presence of human rRNA in the SARS-CoV-2 genome

Defective gene in blood cancers could be treated with already available drugs

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

The zoonotic potential of epidemic porcine deltacoronavirus

Overall survival rate has nearly doubled for Ph+ ALL patients after hematopoietic stem cell transplant

Metabolic vulnerabilities in malignant cells may lead to new breast cancer therapies

Dynamics of hospital-acquired SARS-CoV-2 infection in a geriatric setting

New study reveals why obesity increases the risk of developing cancer

New type of blood test can be used to detect cancers as well as metastatic disease

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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