Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Novel strategy to inactivate Venezuelan equine encephalitis virus

A collaborative team of scientists from the Uniformed Services University of the Health Sciences (USU) and the National Cancer Institute (NCI) have developed a novel strategy to inactivate highly virulent Venezuelan equine encephalitis virus (VEEV) that can infect and kill both animals and humans.

24 Oct 2007

Cellular power plant fault explains abnormal metabolism of tumours

The increased consumption of glucose that tumour cells exhibit, was thought to be a cause of the extra demand of building blocks required to keep up with an uncontrolled cell growth, but now it is more accepted that it could be the effect of a programmed metabolic change that favours this malignant growth.

23 Oct 2007

75% of hospitalised patients suffer from malnutrition regardless of their pathology

A study of 817 patients conducted in the Department of Nutrition and Bromatology at the University of Granada (UGR), in collaboration with the Unit of Nutrition and Dietetics at the hospital Virgen de las Nieves (Granada, Spain) of 817 patients, showed that 75% of hospitalised patients suffer from malnutrition regardless of their pathology.

23 Oct 2007

Transparent zebrafish help the study inflammatory breast cancer

What if doctors could peer through a patient's skin and see a cancer tumor growing? They'd be able to study how tumor cells migrate: how they look, how they interact with the blood system to find nourishment to grow and spread through the body.

22 Oct 2007

Pathogen Simulation provides a new approach to the study of Epstein-Barr virus

Researchers at Tufts University School of Medicine in collaboration with the Virginia Bioinformatics Institute at Virginia Tech have created a computer program called Pathogen Simulation (PathSim) to study the progression of Epstein-Barr virus (EBV) in humans.

22 Oct 2007

The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases

A phenomenon considered healthy for cells, such as the accumulation of long chains of glucose (glycogen), which tissues store for energy purposes, is harmful for neurons.

22 Oct 2007

West Nile virus' spread through nerve cells linked to serious complication

Scientists believe they have found an explanation for a puzzling and serious complication of West Nile virus infection.

19 Oct 2007

Researchers take on E. coli 0157 and salmonella

Understanding the ecology of two dangerous foodborne pathogens and devising ways to combat them is a big job.

17 Oct 2007

Scientists discover how HIV evolves

University of Florida scientists have discovered how HIV evolves over the course of a person's lifetime into a more deadly form that heralds the onset of full-blown AIDS.

17 Oct 2007

Dmp1 gene and lung cancer

The first research to show the involvement of a gene known as Dmp1 in human lung cancer will hopefully lead to an increased understanding on what goes wrong at the cellular level to cause the disease, according to researchers from Wake Forest University School of Medicine reporting in Cancer Cell .

16 Oct 2007

3-D model of the mammary gland reveals secrets of cancer cells

A trans-Atlantic tie up between scientists at the University of Ulster and the Tufts University School of Medicine in Boston could lead to a greater understanding of the triggers that affect cancer cells.

15 Oct 2007

RNA-binding protein key to understanding myotonic dystrophy type 1

Increased levels of a protein called CUGBP1 play an important role in the adult-onset form of muscular dystrophy called myotonic dystrophy type 1, said Baylor College of Medicine researchers in a report that appears in the journal Molecular Cell.

12 Oct 2007

A tumor-blocking protein may be key in developing deadly form of pancreatic cancer

A tumor-blocking protein previously implicated in prostate and breast cancer development may also be behind the most aggressive type of pancreatic cancer. Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have discovered that the protein pp32 – which normally applies the brakes on a cancer-causing gene – is missing in an aggressive form of pancreatic cancer.

12 Oct 2007

Study unravels some of the mystery surrounding the devastating 1918 pandemic

Often called the most devastating epidemic in the recorded history of the world, the 1918 influenza virus pandemic was responsible for more than 40 million deaths across the globe.

10 Oct 2007

Transcutaneous cervical esophageal ultrasound can not substitute for 24-h pH monitoring or manometry

24-h pH monitoring and esophageal manometry are the gold standards of methods used for diagnosing GER and esophageal motor disorders, respectively.

10 Oct 2007

Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals

Researchers have identified which sites and cell types within the respiratory tract are targeted by human versus avian influenza viruses, providing valuable insights into the pathogenesis of these divergent diseases.

10 Oct 2007

One injection of gene therapy spreads through brain in animal study

By targeting a site in a mouse brain well connected to other areas, researchers successfully delivered a beneficial gene to the entire brain - after one injection of gene therapy.

9 Oct 2007

Sir Martin Evans wins Nobel prize for stem cell research

Medical Research Council funded scientist Sir Martin Evans, has been awarded the Nobel Prize in Physiology or Medicine for 2007 alongside Mario R. Capecchi and Oliver Smithies for their discoveries of "principles for introducing specific gene modifications in mice by the use of embryonic stem cells".

9 Oct 2007

Small papillary thyroid cancers are NOT clinically insignificant

Patients with micropapillary thyroid cancer - small tumors equal to or less than 1 centimeter—and tumors even smaller, less than 1 millimeter (mm - are more common and not without a risk as previously thought, according to a new study presented at the 78th Annual Meeting of the American Thyroid Association (ATA) in New York.

8 Oct 2007

Specific immune deficiency pinpointed as likely cause of ulcerative colitis

In a series of mouse experiments, researchers at the Harvard School of Public Health (HSPH) have pinpointed a specific immune deficiency as the likely fundamental cause of ulcerative colitis, a chronic, sometimes severe inflammatory disease of the colon or large intestine that afflicts half a million Americans.

4 Oct 2007