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Implantable heart rhythm monitor does not benefit NSTEMI patients

Patients who received an implantable heart rhythm monitor after suffering a heart attack did not have fewer subsequent cardiovascular events overall, but a subset of patients whose heart attack was classified as non-ST segment elevation myocardial infarction (NSTEMI) did see strong benefits, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Study on the efficacy of a BNT162b2 booster dose in the elderly

In a recent study posted to the medRxiv* preprint server, researchers characterized the immune responses against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant after receiving a booster dose of BNT162b2 vaccine in older people.

5 Apr 2022

Study reveals how pancreatic tumors program macrophages to construct fibrotic barriers

In the presence of pancreatic tumors, certain immune cells break down structural proteins into molecules that trigger the building of dense tissue, a known barrier to therapy, a new study finds.

4 Apr 2022

Firefighters with PTSD often experience interpersonal problems and relationship stress

For firefighters, every day can be an emergency, rushing into flames and disasters as others can only hope to rush out.

4 Apr 2022

Study highlights racial disparities among gastrointestinal cancer patients undergoing surgery

African-American adult patients are more likely than white patients to receive substandard gastrointestinal cancer surgery, according a large study led by researchers at Yale Cancer Center. The findings are reported today in the journal JAMA Network Open.

4 Apr 2022

Vitamin C may help to counteract common side effect of the chemotherapy drug

A study conducted in rats suggests that taking vitamin C may help to counteract the muscle atrophy that is a common side effect of the chemotherapy drug doxorubicin.

4 Apr 2022

Animal study provides insights into how COVID-19 can lead to long-term pain

A new animal study has provided important insights into how COVID-19 SARS-CoV-2 - the virus responsible for COVID-19 - can lead to long-term pain.

4 Apr 2022

Experimental heart failure drug has little impact on exercise tolerance

Heart failure patients taking the investigational drug omecamtiv mecarbil, which has been previously shown to improve long-term outcomes, see little impact on their ability to exercise compared to a placebo, according to a study supported by the Duke Clinical Research Institute.

4 Apr 2022

New type of anti-clotting drug reduces bleeding incidents among patients with atrial fibrillation

A new type of anti-clotting drug caused fewer bleeding incidents among patients with atrial fibrillation than the commonly prescribed apixaban, according to results from a head-to-head comparison of the two.

4 Apr 2022

Case study of multi-system inflammatory syndrome in children in a fully vaccinated teenager

A new preprint describes the importance of recognizing this complication, reporting a case of MIS-C without a prior history of this infection.

4 Apr 2022

Novel rapid genetic test could spare 14,000 newborns from lifelong hearing loss

Clinicians and nurses in neonatal intensive care units (NICU) across Manchester University NHS Foundation Trust (MFT) are the world’s first to deploy genedrive’s MT-RNR1 ID Kit, a new rapid genetic point of care test (POCT) to screen babies for the genetic variant m.1555A>G when admitted with suspected sepsis

4 Apr 2022

COVID-19 study proves ivermectin ineffective

A recent study published in the New England Journal of Medicine investigated the impact of ivermectin, an antiparasitic drug, as an early treatment option among coronavirus disease 2019 (COVID-19) patients.

4 Apr 2022

Addition of alirocumab to high-intensity statin treatment reduces key measures of plaque vulnerability

Compared with a placebo, the addition of the injectable cholesterol-lowering drug alirocumab to high-intensity statin treatment in patients who have had a heart attack resulted in twofold greater reductions in three key measures of plaque vulnerability that signal risk for future cardiac events, according to research presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

While there are effective therapies to reduce the risk of heart disease by lowering low-density lipoprotein (LDL), or "bad" cholesterol, and other lipids, to date there are no approved treatments to lower lipoprotein(a), a lesser-known driver of heart disease risk.

3 Apr 2022

Customized digital alert improves guideline-directed medical therapy for heart failure

Physicians prescribed significantly more guideline-directed medications for heart failure if they received a customized digital alert via an electronic health record (EHR) system when inputting medical orders shortly after seeing a patient, according to a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Experimental heart failure drug does not improve exercise capacity in HFrEF patients

Patients with heart failure with reduced ejection fraction (HFrEF) did not experience any improvement in their ability to exercise vigorously after taking the experimental heart failure drug omecamtiv mecarbil, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Patiromer lowers hyperkalemia risk in heart failure patients taking RAASi therapy

Patients taking renin-angiotensin-aldosterone system inhibitor (RAASi) medications for heart failure had significantly lower blood potassium levels when taking patiromer—a drug that helps to prevent the body from absorbing too much potassium—compared with a placebo, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Cardamonin - a natural compound found in the spice cardamom and other plants - could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells.

3 Apr 2022

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

Scientists develop a formulation for the pulmonary administration of siRNA. The aim was to suppress the replication of SARS-CoV-2.

3 Apr 2022

Therapy News and Research

Implantable heart rhythm monitor does not benefit NSTEMI patients

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Study on the efficacy of a BNT162b2 booster dose in the elderly

Study reveals how pancreatic tumors program macrophages to construct fibrotic barriers

Firefighters with PTSD often experience interpersonal problems and relationship stress

Study highlights racial disparities among gastrointestinal cancer patients undergoing surgery

Vitamin C may help to counteract common side effect of the chemotherapy drug

Animal study provides insights into how COVID-19 can lead to long-term pain

Experimental heart failure drug has little impact on exercise tolerance

New type of anti-clotting drug reduces bleeding incidents among patients with atrial fibrillation

Case study of multi-system inflammatory syndrome in children in a fully vaccinated teenager

Novel rapid genetic test could spare 14,000 newborns from lifelong hearing loss

COVID-19 study proves ivermectin ineffective

Addition of alirocumab to high-intensity statin treatment reduces key measures of plaque vulnerability

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

Customized digital alert improves guideline-directed medical therapy for heart failure

Experimental heart failure drug does not improve exercise capacity in HFrEF patients

Patiromer lowers hyperkalemia risk in heart failure patients taking RAASi therapy

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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