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Brain protein plays a prominent role in the maintenance of chronic pain

A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, according to research conducted at the Icahn School of Medicine at Mount Sinai and published in print October 16, in The Journal of Neuroscience.

11 Oct 2019

Antibody-based eye drop treatment reduces signs and symptoms of dry eye disease

Researchers at the University of Illinois at Chicago are the first to identify the presence of a specific type of antibody, called anti-citrullinated protein autoantibodies, or ACPAs, in human tear fluid.

11 Oct 2019

Extracts from coffee bean skins reduce fat-induced inflammation, insulin resistance in mouse cells

When coffee beans are processed and roasted the husk and silverskin of the bean are removed and unused, and often are left behind in fields by coffee producers.

11 Oct 2019

$RESILIENT study tests benefit of ETA guided treatments for patients with advanced refractory cancers$

RESILIENT study tests benefit of ETA guided treatments for patients with advanced refractory cancers

RESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can offer meaningful clinical benefit for patients with relapsed refractory metastatic malignancies.

11 Oct 2019

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

The authors have developed the Accelera TED platform to repurpose drugs for HNSCC treatment; using in vitro assays and in vivo models.

11 Oct 2019

New findings highlight the 'PrEP gap' for men who have sex with men in the EU

This estimate on the "PrEP gap" in Europe was published in a paper in Eurosurveillance today stating that 500 000 men who have sex with men in the European Union currently cannot access HIV pre-exposure prophylaxis (PrEP), despite being very likely to use it.

11 Oct 2019

UC San Diego's CMCR announces research grants to explore cannabis for medical applications

The Center for Medicinal Cannabis Research (CMCR) at University of California San Diego School of Medicine, the nation's oldest research center for scientific inquiry into the safety and efficacy of cannabis, has announced $3 million in research grants to explore new applications of cannabis for a number of novel medical applications.

11 Oct 2019

Structural biology reveals 3D structure of asthma-linked receptor

A new study has laid bare the structure of a protein receptor called the CysLT1 receptor that is implicated in a range of allergic and cardiovascular conditions as well as some types of cancer. Published in Science Advances, the paper shows how the researchers used structural biology techniques to accomplish this feat.

10 Oct 2019

New coating to improve performance of neural recording technology

A microelectrode array is an implantable device through which neural signals can be obtained or delivered.

10 Oct 2019

Mediterranean style diet found to relieve symptoms of depression

A new study has added to the existing evidence that a healthy and balanced diet could help reduce the symptoms of depression.

10 Oct 2019

Neurofeedback can change guilt-related brain connectivity in patients with Major Depression Disorder

A study published in the journal Neuroimage: Clinical found that patients with Major Depressive Disorder, who had recovered from symptoms, were able to strengthen some of their brain connections whilst thinking about guilt-evoking memories, thereby increasing their self-esteem.

10 Oct 2019

Financial pressure on care homes driving a new trend in choice of mattresses

Over recent months we have noticed a growing trend. Care Homes are increasingly opting for our Simpulse range of mattress systems over their traditional choice of OLA.

From Select Medical 10 Oct 2019

Study shows antibiotic resistance in livestock has almost tripled since 2000

The growing appetite for animal protein in developing countries has resulted in a smorgasbord of antibiotic consumption for livestock that has nearly tripled the occurrence of antibiotic resistance in disease-causing bacteria easily transmitted from animals to humans, according to a recent report in the journal Science.

10 Oct 2019

Dupilumab provides clinical benefit to adolescents with moderate-to-severe atopic dermatitis

Results from a phase IIa open-label trial and a subsequent phase III open-label extension trial reinforce findings from an earlier short-term trial that adolescents with moderate-to-severe atopic dermatitis, or eczema, can experience significant improvements with dupilumab.

9 Oct 2019

Study: The effect of electrical stimulation therapies on spinal fusion

Researchers from The Johns Hopkins University School of Medicine performed a systematic review and meta-analysis of published data on the effect of electrical stimulation therapies on spinal fusion.

9 Oct 2019

Study explores psychological aspects of pain management

An article in the current issue of Psychotherapy and Psychosomatics explores the psychological aspects of pain management with particular reference to placebo infusions in back pain.

8 Oct 2019

Study receives NCI grant to explore better treatment for brain tumors in children

Children with recurrent brain tumors or newly diagnosed, particularly aggressive tumors called diffuse intrinsic pontine gliomas are being enrolled in the first study to examine the efficacy of a drug that inhibits an enzyme these tumors use to protect themselves from the child's natural immune response.

8 Oct 2019

Vaginal fluid transplant could help treat recurring bacterial vaginosis

Bacterial vaginosis is a common and irksome problem for many women. Now researchers have found the transplanting vaginal fluids of a healthy woman to women with troublesome bacterial vaginosis could restore the bacterial microbiome in the latter’s vaginas and thus help treat them.

8 Oct 2019

Federally funded Obria prescribes abstinence to stop the spread of STDs

Inside Obria Medical Clinics, conviction — not condoms — is summoned to stop the spread of chlamydia.

7 Oct 2019

Common genetic variant explains why immunotherapy often fails in Crohn's disease

The reason why a commonly used range of immunotherapy drugs is not effective in some patients with Crohn’s disease has so far not been identified, until now.

7 Oct 2019

Efficacy News and Research

Brain protein plays a prominent role in the maintenance of chronic pain

Antibody-based eye drop treatment reduces signs and symptoms of dry eye disease

Extracts from coffee bean skins reduce fat-induced inflammation, insulin resistance in mouse cells

RESILIENT study tests benefit of ETA guided treatments for patients with advanced refractory cancers

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

New findings highlight the 'PrEP gap' for men who have sex with men in the EU

UC San Diego's CMCR announces research grants to explore cannabis for medical applications

Structural biology reveals 3D structure of asthma-linked receptor

New coating to improve performance of neural recording technology

Mediterranean style diet found to relieve symptoms of depression

Neurofeedback can change guilt-related brain connectivity in patients with Major Depression Disorder

Financial pressure on care homes driving a new trend in choice of mattresses

Study shows antibiotic resistance in livestock has almost tripled since 2000

Dupilumab provides clinical benefit to adolescents with moderate-to-severe atopic dermatitis

Study: The effect of electrical stimulation therapies on spinal fusion

Study explores psychological aspects of pain management

Study receives NCI grant to explore better treatment for brain tumors in children

Vaginal fluid transplant could help treat recurring bacterial vaginosis

Federally funded Obria prescribes abstinence to stop the spread of STDs

Common genetic variant explains why immunotherapy often fails in Crohn's disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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