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Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

25 Jul 2020

Lego-inspired, tiny 3D-printed bricks designed to heal broken bones

Tiny, 3D-printed bricks have been designed to heal broken bones -- and could one day lead to lab-made organs for human transplant.

24 Jul 2020

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Experts use genomic analysis tools to create personalized treatment for kidney cancer patients

Experts at City of Hope and the Translational Genomics Research Institute are using one of the world's most comprehensive genomic analysis tools to map out personalized treatment plans for metastatic kidney cancer patients.

22 Jul 2020

Fusion protein may help treat pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is an insidious disease. Symptoms may begin slowly, and even before they appear, extensive damage has caused the obstruction of small arteries leading to increased blood pressure in the lungs.

21 Jul 2020

Fasting-mimicking diet along with hormone therapy could help treat breast cancer

A USC-led team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat breast cancer, according to newly published animal studies and small clinical trials in humans.

21 Jul 2020

A multi-omics single cell analysis on COVID-19

Now, a new study published on the preprint server medRxiv aims to analyze the immune response over time, using multi-omics in the study of a single cell.

21 Jul 2020

Researchers develop new nano drug that kills triple-negative breast cancer cells

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells.

20 Jul 2020

A new strategy to combat treatment resistance in choroidal neovascularization

An international team of researchers led by Baylor College of Medicine and Houston Methodist has discovered a strategy that can potentially address a major challenge to the current treatment for choroidal neovascularization (CNV), an aggressive form of age-related macular degeneration, the leading cause of irreversible blindness in the elderly.

16 Jul 2020

Study shows how parasitic bacteria cause lesions in the skin and internal organs

Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis."

16 Jul 2020

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

Two new studies led by Renuka Iyer, MD, Section Chief for Gastrointestinal Oncology at Roswell Park Comprehensive Cancer Center, highlight possible new treatment options for patients with neuroendocrine tumors (NETs) - a rare and hard-to-treat cancer.

14 Jul 2020

Research identifies specific brain cells that trigger sugar consumption and cravings

New research has identified the specific brain cells that control how much sugar you eat and how much you crave sweet tasting food.

12 Jul 2020

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

The ongoing COVID-19 pandemic has cost hundreds of thousands of human lives, besides more than 11 million cases. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the disease was initially thought to be more severe in the elderly and those with pre-existing medical conditions. However, it started to manifest in children after the peak of the first wave.

7 Jul 2020

Researchers use nanoparticles to deliver gene therapy for blinding eye disease

In experiments in rats and mice, two Johns Hopkins scientists - an engineer and an ophthalmologist - report the successful use of nanoparticles to deliver gene therapy for blinding eye disease.

7 Jul 2020

Doping agent Epo could be effective against Covid-19

Erythropoietin (Epo) is actually a medication for anaemia. According to researchers at the Max Planck Institute of Experimental Medicine in Göttingen, the doping agent Epo could also be effective against Covid-19.

6 Jul 2020

Newly discovered endometrial cancer biomarker enables early detection and treatment

A newly discovered endometrial (uterine) cancer biomarker and diagnostic method will enable detection of the tumor type that is likely to spread and recur so that clinicians can initiate treatment early and stop the cancer from attacking other parts of the body.

3 Jul 2020

Tiny balls of minerals are better vehicles for promising mRNA-based therapy

University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination -- including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.

2 Jul 2020

Extended culture of human pancreatic slices as a model to study regeneration of beta cells

Scientists from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of "pancreatic slices" to study the regeneration of the human pancreas in real time.

1 Jul 2020

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that IQGAP1 is a signaling scaffold implicated in TNBC, but its mechanism is unknown.

30 Jun 2020

Stanford's Nobel Laureate develops a prediction model for SARS-CoV-2

The researchers from Stanford School of Medicine and ShangaiTech University show that the growth of a coronavirus disease (COVID-19) outbreak does not behave in accordance with an exponential growth law, but instead slows down exponentially with time from the very first days. Their thought-provoking findings can be currently found in the medRxiv* preprint server.

29 Jun 2020

Growth Factor News and Research

Higher levels of TGFBIp are correlated with severity of COVID-19 symptoms

Lego-inspired, tiny 3D-printed bricks designed to heal broken bones

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Experts use genomic analysis tools to create personalized treatment for kidney cancer patients

Fusion protein may help treat pulmonary arterial hypertension

Fasting-mimicking diet along with hormone therapy could help treat breast cancer

A multi-omics single cell analysis on COVID-19

Researchers develop new nano drug that kills triple-negative breast cancer cells

A new strategy to combat treatment resistance in choroidal neovascularization

Study shows how parasitic bacteria cause lesions in the skin and internal organs

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

Research identifies specific brain cells that trigger sugar consumption and cravings

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

Researchers use nanoparticles to deliver gene therapy for blinding eye disease

Doping agent Epo could be effective against Covid-19

Newly discovered endometrial cancer biomarker enables early detection and treatment

Tiny balls of minerals are better vehicles for promising mRNA-based therapy

Extended culture of human pancreatic slices as a model to study regeneration of beta cells

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

Stanford's Nobel Laureate develops a prediction model for SARS-CoV-2

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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