Efficacy News and Research

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Web-based, digital-app birth control prescription services appear to be overall safe and efficient

Web-based and digital-app services that offer oral contraception appear to be overall safe and efficient, according to the findings of a secret-shopper-style study conducted by researchers at Harvard Medical School and UC Davis that analyzed the birth control prescription services of nine U.S. vendors.

26 Sep 2019

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Children's of Alabama is home to one of the most exciting studies underway in pediatric cancer: evaluating the use of a cold sore virus to treat children with progressive malignant brain tumors.

26 Sep 2019

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

An international, multicenter phase II clinical trial is evaluating the efficacy and safety of mavrilimumab co-administered with a 26-week corticosteroid taper in patients with giant cell arteritis.

26 Sep 2019

UCI researchers receive BRAIN Initiative grant to lead development of new brain mapping tool

Professors Xiangmin Xu and Rozanne Sandri-Goldin, in collaboration with Professors Bert Semler and Todd Holmes at the University of California, Irvine, School of Medicine, were awarded a three-year, $4.3 million Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative grant.

26 Sep 2019

New tool for healthcare providers to combat obesity in primary care settings

Healthcare practitioners and researchers have a new tool to combat obesity in primary care settings, according to a study published in Obesity, the flagship journal of The Obesity Society.

24 Sep 2019

Migraine knowledge poor among university students

Migraine is a particularly agonizing condition, much more than a simple headache, affecting 5% to 12% of the population. However, the condition is not diagnosed in many patients, forcing them to undergo severe pain for years on end. One of the causes for this widespread under-diagnosis is the lack of knowledge of the features that distinguish a migraine from a non-migraine headache.

24 Sep 2019

Green tea compound shows promise in tackling antibiotic resistance

Green tea has gained immense popularity across the globe, mainly because of its health benefits. Green tea extract has been used for many purposes – for weight loss, improved brain function, enhanced metabolism, and lower risk of some types of cancer, among others.

24 Sep 2019

The biological clock modulates immune response efficiency, study shows

According to a recent study published in Proceedings of the National Academy of Sciences of the United States of America, the biological clock influences immune response efficacy. Indeed, CD8 T cells, which are essential to fight infections and cancers, function very differently according to the time of day.

24 Sep 2019

$Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus$

Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus

Researchers from the University of California San Francisco and Veterans Affairs Health Care System, San Francisco investigated the safety and efficacy of deep brain stimulation in the treatment of refractory severe tinnitus in a small group of patients.

24 Sep 2019

New microcapsules provide safe and effective delivery of drugs, biomolecules

Cracking an egg to release its yolk requires applying external force (like being smacked against the edge of a bowl) to overcome the strength of the eggshell.

24 Sep 2019

New drug delivery system could be a boon for those on a multi-drug regimen

Researchers from the University of North Carolina at Chapel Hill have developed a unique new multi-drug delivery system that could p-rove to be useful for persons who need to take several drugs in a day as part of a regimen.

23 Sep 2019

Unexpected mechanism of action found with sertraline

A new study on sertraline, which is one of the most popular drugs for depression and anxiety, shows that its efficacy is undoubted, but it operates primarily by reducing anxiety rather than depression.

23 Sep 2019

Advancing towards 100% effective herpes vaccine

Genital herpes, caused by the herpes simplex virus 2 (HSV-2) is a very common sexually transmitted infection (STI). It affects 14% of Americans aged 15-49 years. There is no herpes vaccine at present. Many failed attempts at vaccine production have centered around HSV proteins.

23 Sep 2019

How moral distress leads to erosion of clinicians' moral strength in health care systems

Nurse burnout impacts both nurses and patients, and significantly influences the retention of nurses in the healthcare setting, research shows. But could burnout be a symptom of something larger?

23 Sep 2019

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.

23 Sep 2019

2019 ASTMH Annual Meeting to focus on Ebola, monkey malaria, and other infectious diseases

This year's meeting will kick off with keynotes from two public health heroes who have pioneered a home-based approach to fighting infant mortality in India that's now being adopted in 10 countries.

23 Sep 2019

Cutting-edge technologies to improve drug development while reducing animal testing

On Thursday, September 19th, 2019, the Physicians Committee for Responsible Medicine hosted a congressional briefing in cooperation with Rep. Brendan Boyle (D-Pa.), featuring innovator companies showcasing cutting-edge technologies that have the potential to improve the safety and efficacy of pharmaceuticals while reducing animal testing.

20 Sep 2019

Efficacy News and Research

Web-based, digital-app birth control prescription services appear to be overall safe and efficient

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

UCI researchers receive BRAIN Initiative grant to lead development of new brain mapping tool

New tool for healthcare providers to combat obesity in primary care settings

Migraine knowledge poor among university students

Green tea compound shows promise in tackling antibiotic resistance

The biological clock modulates immune response efficiency, study shows

Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus

New microcapsules provide safe and effective delivery of drugs, biomolecules

New drug delivery system could be a boon for those on a multi-drug regimen

Unexpected mechanism of action found with sertraline

Advancing towards 100% effective herpes vaccine

How moral distress leads to erosion of clinicians' moral strength in health care systems

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

2019 ASTMH Annual Meeting to focus on Ebola, monkey malaria, and other infectious diseases

Cutting-edge technologies to improve drug development while reducing animal testing

Penn researchers develop novel vaccine to protect against genital herpes

A single dose of yellow fever vaccine does not offer long-term immunity to children

Fluoride varnish: is there any benefit?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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