Immune System News and Research

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Study reveals key role of actin cytoskeletal dynamics in supporting immune cell function

In order to move, a body needs a strong scaffold. This is not only true on a macroscopic level, where animals rely on skeletons to support their muscles.

26 Jul 2018

Study observes how nanoplastics cause damage to DNA and cell membranes in mussels

Plastic pollution is a worldwide environmental problem which worsens when this material degrades into smaller-sized particles such as microplastics and nanoplastics, the latter capable of penetrating into an organism's cells.

26 Jul 2018

Long-lasting HIV control without antiretroviral therapy is a feasible goal, says expert

Long-lasting control of HIV infection without antiretroviral therapy is a feasible goal that deserves vigorous pursuit, Anthony S. Fauci, M.D., will assert during a lecture on Wednesday, July 25 at the 22nd International AIDS Conference in Amsterdam.

26 Jul 2018

Initiation of early treatment in HIV-infected infants has undeniable benefits

The initial findings of the ANRS CLEAC study coordinated by Pierre Frange (Hôpital Necker - AP-HP), help define the immunological and virological benefits of early antiretroviral therapy in HIV-infected children living in France.

25 Jul 2018

Omeros’ OMS721 receives positive opinion from EMA's COMP for treating hematopoietic stem cell transplant

Omeros Corporation announced today that the European Medicines Agency's Committee for Orphan Medicinal Products issued a positive opinion recommending orphan drug designation of OMS721 for treatment in hematopoietic stem cell transplantation.

25 Jul 2018

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

Researchers identify gene from Ebola virus in Myotis bats

A gene from the deadly Ebola virus that allows the virus to escape from the human immune system has been identified in the genome of a group of bats that is found worldwide, including North America.

25 Jul 2018

Researchers discover how antibodies secreted in the gut promote growth of healthy microbiome

Researchers at the RIKEN Center for Integrative Medical Science in Japan have discovered how antibodies secreted in the gut promote the growth of beneficial bacteria.

25 Jul 2018

Single course of antibiotics early in childhood may increase risk for Type 1 diabetes

A single course of antibiotics early in childhood may increase risk for Type 1 diabetes. This is the finding of a study in mice led by researchers from NYU Medical School and published online July 24 in the journal eLife.

25 Jul 2018

Study shows bats co-opted genes from ancient ebola like virus million years ago

Some 18 million years ago, an ancestor of mouse-eared bats "stole" genetic material from an ancient virus related to Ebola.

25 Jul 2018

New research uncovers AEP enzyme's importance to immunity

The importance of the enzyme AEP as a key regulatory of the immune system has been discovered in new research from Newcastle University, UK.

24 Jul 2018

Study highlights clear need for innovation to increase transplanted kidney's lifespan

The lifespan of a transplant kidney has significantly improved over the last thirty years. Between 1986 and 1995, 75% of the transplanted kidneys still functioned five years after the transplant. Between 2006 and 2015, this number had already risen to 84%.

24 Jul 2018

Researchers report first randomized trial results of 'kick and kill' approach to treat HIV

Researchers have reported the results of the first randomized clinical trial to test a novel strategy involving waking up and then killing the 'sleeping' HIV that is hiding in the body using an experimental approach known as 'kick and kill'.

24 Jul 2018

New study provides important clues to developing more effective Ebola vaccines

Scientists conducting the first comprehensive study of key immune system cells - collected from West African Ebola survivors that kill Ebola infected cells have made a surprising discovery that provides important clues to developing effective vaccines against the infection.

24 Jul 2018

Discovery about how malaria moves could lead to new therapies

Researchers have made an important discovery about how Plasmodium falciparum (the parasite that causes malaria) is able to evade capture by the immune system.

23 Jul 2018

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation.

20 Jul 2018

Study uncovers molecular key for delaying progression of multiple sclerosis

Multiple Sclerosis is an autoimmune disease that attacks and destroys a structure known as the "myelin sheath", whose integrity is indispensable for the brain and spinal cord to function properly.

20 Jul 2018

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

CRISPR, or clustered regularly interspaced short palindromic repeats, are an essential part of bacterial immunity designed to defend against foreign DNA. In bacteria, CRISPR acts just like it does in human cells as a pair of scissors, in their case with the goal of cutting strands of infecting DNA.

20 Jul 2018

Scientists find reason why malarial parasites are faster than immune cells

Elementary cytoskeleton protein is different in parasites and represents a starting point for a possible new therapy against malaria infections.

20 Jul 2018

New vaccine could protect unborn babies from Zika virus

Until recently, the Zika virus was not a priority since it affected relatively few people and the cost of creating a vaccine was estimated at EUR 149-468 million. But the spread of Zika in the Americas and discovery of a link with reduced head size and brain damage in babies of women infected while pregnant changed that.

20 Jul 2018

Immune System News and Research

Study reveals key role of actin cytoskeletal dynamics in supporting immune cell function

Study observes how nanoplastics cause damage to DNA and cell membranes in mussels

Long-lasting HIV control without antiretroviral therapy is a feasible goal, says expert

Initiation of early treatment in HIV-infected infants has undeniable benefits

Omeros’ OMS721 receives positive opinion from EMA's COMP for treating hematopoietic stem cell transplant

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Researchers identify gene from Ebola virus in Myotis bats

Researchers discover how antibodies secreted in the gut promote growth of healthy microbiome

Single course of antibiotics early in childhood may increase risk for Type 1 diabetes

Study shows bats co-opted genes from ancient ebola like virus million years ago

New research uncovers AEP enzyme's importance to immunity

Study highlights clear need for innovation to increase transplanted kidney's lifespan

Researchers report first randomized trial results of 'kick and kill' approach to treat HIV

New study provides important clues to developing more effective Ebola vaccines

Discovery about how malaria moves could lead to new therapies

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

Study uncovers molecular key for delaying progression of multiple sclerosis

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

Scientists find reason why malarial parasites are faster than immune cells

New vaccine could protect unborn babies from Zika virus

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