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Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Study highlights need to categorize stillbirths for improving outcomes for families

Forty two babies are stillborn in Australia every week, and 60 percent of them are recorded as “unexplained”.

5 Dec 2017

Blood pressure begins to decrease about 14 years before death, study finds

Blood pressure in the elderly gradually begins to decrease about 14 or so years before death, according to a new study published today in the Journal of the American Medical Association Internal Medicine.+

5 Dec 2017

Penn study: New dental material kills bacteria and resists biofilm growth

Dentists rely on composite materials to perform restorative procedures, such as filling cavities. Yet these materials, like tooth enamel, can be vulnerable to the growth of plaque, the sticky biofilm that leads to tooth decay.

5 Dec 2017

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

For prostate cancer patients who have rising levels of PSA (a cancer indicator) even after radical prostatectomy, early treatment makes a difference.

5 Dec 2017

Neurons have compatible shape, electrical properties for deep learning

Deep learning has brought about machines that can 'see' the world more like humans can, and recognize language. And while deep learning was inspired by the human brain, the question remains: Does the brain actually learn this way? The answer has the potential to create more powerful artificial intelligence and unlock the mysteries of human intelligence.

5 Dec 2017

Physicians' experiences with patients, family linked to breast cancer screening recommendations

Results of a national survey of more than 800 physicians suggest that their experiences with patients, family members and friends with breast cancer are linked with their recommendations for routine mammograms.

4 Dec 2017

Scientists investigate new role of old protein in breast cancer

Scientists led by Dr Chris Toseland of the University's School of Biosciences studied a protein called Myosin VI, a molecular motor which acts as a courier to transport other proteins within our cells.

4 Dec 2017

Study finds high levels of psychological distress among surrogate decision makers

Nearly half of the 13 million older adults hospitalized annually in the United States are unable to make their own medical decisions and rely on surrogates, usually close family members, to make decisions for them. However little is known about how these surrogates respond to the demands put upon them.

4 Dec 2017

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Children with an extremely deadly form of brain cancer might benefit from a new treatment that aims to direct an immune response against an abnormally shaped protein found exclusively on cancer cells, according to a new study led by UC San Francisco researchers.

4 Dec 2017

OICR announces innovative initiative to drive development of new cancer therapies

The Ontario Institute for Cancer Research today announced the Cancer Therapeutics Innovation Pipeline initiative and the first 10 projects selected in CTIP's inaugural round of funding.

4 Dec 2017

Parental attention can be protective factor to lower risk of drug abuse among adolescents

Parents who require children to follow rules and keep a constant eye on their activities, endeavoring to know where they are, who they are with and what they are doing, run less risk of facing problems when their children enter adolescence, such as abuse of alcohol and other drugs.

4 Dec 2017

New high-density EEG captures neural activity at higher spatial resolution than ever before

Carnegie Mellon University engineers and cognitive neuroscientists have demonstrated that a new high-density EEG can capture the brain's neural activity at a higher spatial resolution than ever before.

4 Dec 2017

Penn Medicine's first-of-its-kind app aims to enhance care for bariatric surgery patients

For many patients on the road to bariatric surgery, the process may seem daunting: track steps and exercise, record caloric and water intake, monitor sleep time, alter diet, etc. Pair this daily lifestyle management with clinic appointments, evaluations, and the stress that often comes with any kind of surgery, and patients may become too overwhelmed to move forward with their goals.

4 Dec 2017

New study finds serious mental health risks among Yemenis

Yemenis face serious mental health risks, but the issue is being neglected, says a new study released today by Columbia University's Mailman School of Public Health and the Sana'a Center for Strategic Studies, Columbia Law School's Human Rights Clinic.

4 Dec 2017

Research shows how cells rebuild nucleus, organize genome after division

University of Bristol research has revealed how cells rebuild their nucleus and organise their genome when they divide - a discovery which could have major implications for understanding cancer and degeneration.

4 Dec 2017

New approaches show promise to fight against drug-resistant superbugs in hospitals

If you visit a doctor's surgery or hospital you may be asked to apply a hand sanitizer upon entry. Strict hand hygiene practices have become one of the most essential activities in the battle against reducing multi-drug resistant infections in hospitals, nursing homes, and other healthcare settings.

4 Dec 2017

Study finds altered blood flow in brains of preterm newborns

According to a new prospective and observational study published today in The Journal of Pediatrics, very premature infants suffer from an altered cerebral blood flow (CBF) of key regions of the brain which may help to warn of complications in brain maturation, far sooner than conventional imaging could visually reveal.

4 Dec 2017

Study shows connection between common hypertension drug and skin cancer

Recently published research from The University of Southern Denmark and the Danish Cancer Society shows a connection between one of the most common medications for hypertension and skin cancer.

4 Dec 2017

Kent researchers establish first long-term cultivation system for diarrhea-causing parasite

A research team at the University of Kent has established the first long-term cultivation system at a laboratory scale for the parasite Cryptosporidium, one of the world's worst and most common causes of diarrhea and death from diarrhea.

4 Dec 2017

Research News and Research

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

Study highlights need to categorize stillbirths for improving outcomes for families

Blood pressure begins to decrease about 14 years before death, study finds

Penn study: New dental material kills bacteria and resists biofilm growth

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

Neurons have compatible shape, electrical properties for deep learning

Physicians' experiences with patients, family linked to breast cancer screening recommendations

Scientists investigate new role of old protein in breast cancer

Study finds high levels of psychological distress among surrogate decision makers

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

OICR announces innovative initiative to drive development of new cancer therapies

Parental attention can be protective factor to lower risk of drug abuse among adolescents

New high-density EEG captures neural activity at higher spatial resolution than ever before

Penn Medicine's first-of-its-kind app aims to enhance care for bariatric surgery patients

New study finds serious mental health risks among Yemenis

Research shows how cells rebuild nucleus, organize genome after division

New approaches show promise to fight against drug-resistant superbugs in hospitals

Study finds altered blood flow in brains of preterm newborns

Study shows connection between common hypertension drug and skin cancer

Kent researchers establish first long-term cultivation system for diarrhea-causing parasite

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