Small Molecules News and Research

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NASA’s Twins Study researchers explore the ground truth behind metabolites

You may think you're just an average Joe, but according to your metabolomics data your body is percolating some expressive information about your daily life.

24 Aug 2017

Scientists reveal existence of alternative bacterial quorum-sensing mechanism

Whether growing in a puddle of dirty water or inside the human body, large groups of bacteria must coordinate their behavior to perform essential tasks that they would not be able to carry out individually.

21 Aug 2017

New vaccine could offer protection against opioid combinations

Substance abuse is a continuing problem in the U.S., particularly with heroin and other opioids, to the point of being an epidemic.

21 Aug 2017

Some people better than others at recovering from wounded heart, says USC study

Some people are better than others at recovering from a wounded heart, according to a new USC Stem Cell study published in Nature Genetics.

7 Aug 2017

Researchers develop set of tools to trace path of proteins linked to Parkinson's disease

As neurodegenerative disorders such as Parkinson's and Alzheimer's disease progress, misfolded proteins clump together in neurons, recruiting normal proteins in the cell to also misfold and aggregate.

4 Aug 2017

Sheffield scientists discover that simple arthritis drug could help treat blood cancer sufferers

Blood cancer sufferers could be treated with a simple arthritis drug, scientists at the University of Sheffield have discovered.

3 Aug 2017

Vanderbilt scientists find new way to destroy microbial vampires

On July 24 Vanderbilt scientist Eric Skaar, Ph.D., MPH, summarized his group's latest paper in a tweet: "If S. aureus is going to drink our blood like a vampire, let's kill it with sunlight."

1 Aug 2017

Synthetic molecule can disrupt hunger-signaling pathway, research suggests

New research suggests that a man-made cousin of a small molecule found in olive oil can disrupt the hunger-signaling pathway.

27 Jul 2017

Research suggests novel approach for encouraging regeneration in mouse retina

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows.

27 Jul 2017

MIT engineers design new gel coatings that may lead to better medical devices

Catheters, intravenous lines, and other types of surgical tubing are a medical necessity for managing a wide range of diseases. But a patient's experience with such devices is rarely a comfortable one.

19 Jul 2017

Salford scientists may have found simple way for designing new antibiotics

CANCER researchers in the UK may have stumbled across a solution to reverse antibiotic drug resistance and stop infections like MRSA.

12 Jul 2017

Computational analysis of open-access data points to new ways of using drugs

A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.

12 Jul 2017

$Promising target may open door to new therapies for preventing bone fractures in diabetes patients$

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes.

7 Jul 2017

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Meeting a young patient with Zellweger syndrome, a rare, life-threatening genetic disease, started a scientific investigation that culminated with an unexpected discovery.

23 Jun 2017

New algorithm shortens drug discovery times from years to months

An algorithm developed at the Hebrew University cuts through the immense number of possible solutions to shorten drug discovery times from years to months.

22 Jun 2017

TSRI scientist and partners receive $7.2 million grant to create new RNA-based treatments for ALS

Professor Matthew Disney of the Department of Chemistry on the Florida campus of The Scripps Research Institute, together with scientists from Mayo Clinic's Florida campus and Johns Hopkins School of Medicine, has been awarded $7.2 million from the National Institute of Neurological Disorders and Stroke of The National Institutes of Health to create new RNA-based treatments for the most common form of amyotrophic lateral sclerosis (ALS), as well as a type of frontotemporal dementia (FTD).

15 Jun 2017

New research could help mitigate effects of radiation therapy

New research conducted at the University of Kansas Medical Center could make treatment for gastrointestinal cancers safer- while also helping to mitigate the dangers of nuclear accidents and terrorist attacks.

14 Jun 2017

Researchers find molecule that darkens skin without UV exposure and may protect against skin cancer

A study published in the journal Cell on June 13 has found that a class of small molecules can successfully penetrate and darken human skin samples. The drug developed in the laboratory by researchers in Boston also generates protective tans in red-haired mice.

14 Jun 2017

Vitamin A improves insulin-producing beta-cells' function, study suggests

There has been no known link between diabetes and vitamin A - until now. A new study suggests that the vitamin improves the insulin producing β-cell´s function.

13 Jun 2017

Rice scientists use magnets and nanoparticles to make vessels temporarily ‘leaky’

The endothelial cells that line blood vessels are packed tightly to keep blood inside and flowing, but scientists at Rice University and their colleagues have discovered it may be possible to selectively open gaps in those barriers just enough to let large molecules through -- and then close them again.

8 Jun 2017