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DNA aptamer-based sensors can accurately detect trace amounts of fentanyl, heroin, and cocaine

Researchers from North Carolina State University have developed a new generation of high-performance DNA aptamers and highly accurate drug sensors for cocaine and other opioids.

5 Mar 2024

New method simplifies production of limb progenitor cells from fibroblasts

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts - the most commonly found cells in skin and connective tissue - into cells with similar properties to limb progenitor cells.

4 Mar 2024

New method revolutionizes in vivo brain imaging in awake mice

The human brain has billions of neurons. Working together, they enable higher-order brain functions such as cognition and complex behaviors.

4 Mar 2024

The impact of quinoa bioactive compounds on gut health

Researchers review the beneficial impacts of quinoa and its bioactive compounds, particularly its effects on intestinal microflora.

4 Mar 2024

Gut bacteria diversity linked to body weight, athletes show healthier profiles

Systematic review reveals gut microbiome variations correlate with body composition changes across lifespan, highlighting differences between obese individuals and athletes.

29 Feb 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

Interdisciplinary project aims to decode human kinome in brain function and disease

The Chan Zuckerberg Initiative (CZI) announced four multi-year Exploratory Cell Networks grants for researchers exploring the frontiers of genomics, cell biology, and synthetic biology by developing new measurement technologies.

29 Feb 2024

Breakthrough CRISPR technique unlocks insights about cancer immunology

Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer.

29 Feb 2024

NIH funds study on neural mechanisms behind autism and sound sensitivity

Supported by a $2 million R01 grant from the National Institutes of Health, the Auerbach Lab at the Beckman Institute for Advanced Science and Technology will examine how different genes associated with autism spectrum disorders may similarly impact our brain's neurons, resulting in heightened sensitivity to sounds.

28 Feb 2024

New lung cell atlas unveils pathways to lung adenocarcinoma development

Researchers at The University of Texas MD Anderson Cancer Center built a new atlas of lung cells, uncovering new cellular pathways and precursors in the development of lung adenocarcinoma, the most common type of lung cancer.

28 Feb 2024

Genetic studies shed light on hypertension risk but fall short of revealing new treatments

Genetic variant research in hypertension has identified numerous associations but is unlikely to yield new treatments, emphasizing the gap between scientific discovery and clinical application.

27 Feb 2024

Optibrium launches a metabolism prediction software platform tailored to DMPK scientists

Semeta™ offers high sensitivity and superior precision for the prediction of Phase I and II metabolic routes, sites, products and liabilities in early drug discove.ry

From Optibrium Ltd. 27 Feb 2024

Neuropsychiatric symptoms can be potential predictors of Alzheimer's development

As the years add up, it's common to notice slight changes in our ability to remember and think. Older people who have more marked changes than their peers can be diagnosed with mild cognitive impairment (MCI).

26 Feb 2024

Globe artichokes: A rich source of dietary fiber and phenolic antioxidants

The clinical and nutraceutical health benefits of Cynarra scolymus, the globe artichoke.

26 Feb 2024

Researchers uncover crucial role of collateral blood vessels in stroke recovery

Blood vessels that cross-connect adjacent arterial trees regulate blood flow to the brain in stroke patients.

26 Feb 2024

“Laboratory testicles” could solve male infertility mysteries

The testis is responsible for sperm production and testosterone synthesis. Abnormalities in testis development and function lead to disorders of sex development (DSD) and male infertility. Currently, no in vitro system exists for modeling the testis.

20 Feb 2024

Ultrahigh-spatial-resolution PCD-CT improves assessment of coronary artery disease

Ultrahigh-spatial-resolution photon-counting detector CT improved assessment of coronary artery disease (CAD), allowing for reclassification to a lower disease category in 54% of patients, according to a new study published today in Radiology, a journal of the Radiological Society of North America.

20 Feb 2024

A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries

Researchers conducted clinical studies on murine animals and humans to evaluate the impact of high protein intake on the amino acid-mammalian target of the rapamycin complex 1 autophagy signaling pathway.

19 Feb 2024

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Researchers utilized an untargeted metabolomics technique to look for new compounds and pathways that may contribute to residual cardiovascular disease risk.

19 Feb 2024

Identification of genetic determinants of micronucleus formation

The genetic determinants of micronuclei formation (MN).

19 Feb 2024

in vivo News and Research

DNA aptamer-based sensors can accurately detect trace amounts of fentanyl, heroin, and cocaine

New method simplifies production of limb progenitor cells from fibroblasts

New method revolutionizes in vivo brain imaging in awake mice

The impact of quinoa bioactive compounds on gut health

Gut bacteria diversity linked to body weight, athletes show healthier profiles

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Interdisciplinary project aims to decode human kinome in brain function and disease

Breakthrough CRISPR technique unlocks insights about cancer immunology

NIH funds study on neural mechanisms behind autism and sound sensitivity

New lung cell atlas unveils pathways to lung adenocarcinoma development

Genetic studies shed light on hypertension risk but fall short of revealing new treatments

Optibrium launches a metabolism prediction software platform tailored to DMPK scientists

Neuropsychiatric symptoms can be potential predictors of Alzheimer's development

Globe artichokes: A rich source of dietary fiber and phenolic antioxidants

Researchers uncover crucial role of collateral blood vessels in stroke recovery

“Laboratory testicles” could solve male infertility mysteries

Ultrahigh-spatial-resolution PCD-CT improves assessment of coronary artery disease

A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Identification of genetic determinants of micronucleus formation

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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