Protein C News and Research

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Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

A recent study assessed the role of the SARS-CoV-2 Omicron spike H655Y mutation on viral entry pathways.

24 Mar 2022

Study evaluates mutation-induced SARS-CoV-2 spike protein fold stability

Researchers evaluated the stability and expression of mutations in the spike protein of SARS-CoV-2.

24 Mar 2022

$Study finds fractionation of sulfated galactan from red alga can isolate its anti-SARS-CoV-2 properties$

Study finds fractionation of sulfated galactan from red alga can isolate its anti-SARS-CoV-2 properties

A new study analyzed BoSG and its low molecular weight derivatives for their anticoagulant, anti-SARS-CoV-2, S-protein binding, and structural properties.

24 Mar 2022

Anti-spike SARS-CoV-2 antibody titer trends over 15 months in healthcare workers in Boston

Researchers assessed the changes in the immunoglobulin titers against the receptor-binding domain of the spike protein of SARS-CoV-2 post-vaccination and natural SARS-CoV-2 infection in healthcare workers of Boston.

24 Mar 2022

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

A recent study demonstrated that RNA interference could prophylactically protect against SARS-CoV-2.

24 Mar 2022

Uptake of SARS-CoV-2 spike protein in human cerebrovascular cells

A recent study assessed the uptake of SARS-CoV-2 spike protein in human cerebrovascular cells via the lipid raft ganglioside.

24 Mar 2022

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

Sino Biological is pleased to announce a CRO services partnership with Ainnocence, Inc. of San Jose, California.

From Sino Biological Inc. 24 Mar 2022

Non-hormonal male contraceptive effectively prevents pregnancy in mice

Women have many choices for birth control, ranging from pills to patches to intrauterine devices, and partly as a result, they bear most of the burden of preventing pregnancy.

24 Mar 2022

Mineralocorticoid receptor antagonist use linked to improved renal prognosis in CKD patients

Just as a water filtration system acts to filter contaminants from the water you drink, your kidneys act to filter waste and excess fluid from your blood.

24 Mar 2022

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Scientists from the United States have recently assessed the evolutionary success of mutations accumulated across severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. They have observed that the positively-selected mutations in the viral spike S1 subunit are primarily responsible for adaptive evolution. This indicates that the virus may undergo antigenic drift.

23 Mar 2022

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

23 Mar 2022

Scientists develop first drug to treat uncontrolled secretion of mucins in the airways

A multicenter research team co-led by The University of Texas MD Anderson Cancer Center developed the first drug to treat the uncontrolled secretion of mucins in the airways, which causes potentially life-threatening symptoms in millions of Americans with asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF), as well as lung disease resulting from cancer and cancer treatment.

23 Mar 2022

T-cell and neutralizing antibody response after a third COVID-19 vaccine dose in hemodialysis patients

Researchers compare the impact of a third mRNA COVID-19 vaccine in hemodialysis patients by measuring antibody levels and IFN-γ responses.

23 Mar 2022

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Researchers discuss alternate therapeutic targets for treating COVID-19 and the effects of Gal-9 on SARS-CoV-2 infection and the immune response.

23 Mar 2022

Study confirms no preexisting B-cell immunity against SARS-CoV-2 in pre-pandemic samples

A recent study finds that there is no considerable B-cell immunity against SARS-CoV-2 in unexposed healthy individuals.

23 Mar 2022

FDA approves new treatment for patients with metastatic melanoma based on Johns Hopkins research

The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer.

23 Mar 2022

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

There is likely recombination of genome sequences between the SARS-CoV-2 Delta and Omicron variants in their spike (S) protein.

23 Mar 2022

New nanoparticle-based COVID-19 vaccine platform could target other infectious diseases

Just one dose of a new nanoparticle-based COVID-19 vaccine was enough to produce an immune response in animals on track with vaccines currently in clinical use.

23 Mar 2022

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

A University of Iowa neuroscience research team has identified a fundamental biochemical mechanism underlying memory storage and has linked this mechanism to cognitive deficits in mouse models of Alzheimer's Disease and Related Dementias.

23 Mar 2022

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

The National Cancer Institute, part of the National Institutes of Health, recently awarded a five-year, $ $1.9 million grant to C. Patrick Reynolds, M.D., Ph.D., director for the School of Medicine Cancer Center at the Texas Tech University Health Sciences Center.

23 Mar 2022

Protein C News and Research

Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

Study evaluates mutation-induced SARS-CoV-2 spike protein fold stability

Study finds fractionation of sulfated galactan from red alga can isolate its anti-SARS-CoV-2 properties

Anti-spike SARS-CoV-2 antibody titer trends over 15 months in healthcare workers in Boston

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

Uptake of SARS-CoV-2 spike protein in human cerebrovascular cells

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

Non-hormonal male contraceptive effectively prevents pregnancy in mice

Mineralocorticoid receptor antagonist use linked to improved renal prognosis in CKD patients

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Scientists develop first drug to treat uncontrolled secretion of mucins in the airways

T-cell and neutralizing antibody response after a third COVID-19 vaccine dose in hemodialysis patients

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Study confirms no preexisting B-cell immunity against SARS-CoV-2 in pre-pandemic samples

FDA approves new treatment for patients with metastatic melanoma based on Johns Hopkins research

Recombinant SARS-CoV-2 Delta-Omicron variant identified in the United States

New nanoparticle-based COVID-19 vaccine platform could target other infectious diseases

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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