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New type of treatment for osteoarthritis shows promise for use in humans

A new type of treatment for osteoarthritis, currently in canine clinical trials, shows promise for eventual use in humans.

20 Jun 2019

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment's cause and develop a potential and desperately needed nanoparticle-based treatment.

19 Jun 2019

Highlights and key takeaways from the 2019 Boston Bacterial Meeting (BBM)

Missed out on the 2019 Boston Bacterial Meeting (BBM)? Read our round-up of the key takeaways, areas of discussion, speakers and more.

19 Jun 2019

Researchers discover redundancies in immune cells

Researchers at ETH Zurich have discovered redundancies in the biochemical signaling pathways of immune cells. This finding has important implications for advances in cancer immunotherapy, among other areas.

18 Jun 2019

Anti-aging study wins grant from William and Ella Owens Medical Research Foundation

The William and Ella Owens Medical Research Foundation has awarded Texas Biomed Associate Professor Marcel Daadi, Ph.D., with a grant of more than $100,000 to test a promising FDA-approved drug for reversing age-related cognitive decline and memory deficits observed in aged baboons.

18 Jun 2019

Consortium receives EU grant to develop new treatment for leishmaniasis

Professor Sanjeev Krishna and colleagues at St George's, University of London are heading a consortium that has been awarded EUR3.75 million to develop a treatment for one of the world's most neglected tropical diseases, leishmaniasis.

18 Jun 2019

Researchers develop promising reconstruction method based on 3D-printed esophageal grafts

The loss of complete segments of the esophagus often results from treatments for esophageal cancer or congenital abnormalities, and current methods to re-establish continuity are inadequate.

18 Jun 2019

FDA approves first non-insulin drug for treatment of pediatric patients with type 2 diabetes

The U.S. Food and Drug Administration today approved Victoza (liraglutide) injection for treatment of pediatric patients 10 years or older with type 2 diabetes.

18 Jun 2019

New experimental system can rapidly assess pathogenic effects of a drug on baby's brain

Pregnant women are often advised to avoid certain drugs because of potential risks to their unborn infant's growing brain cells.

18 Jun 2019

Topical cream found to be effective in reversing the effects of vitiligo

A nationwide phase II clinical trial, coordinated out of Tufts Medical Center in Boston, has found that a topical cream was extremely effective in reversing the effects of vitiligo, a relatively common autoimmune disease that causes loss of skin pigmentation.

17 Jun 2019

Harvard chemists achieve landmark in drug discovery with synthesis of potent anti-cancer agent

It's a feat three decades in the making: Harvard University chemists have achieved what a new paper calls a "landmark in drug discovery" with the total synthesis of halichondrin.

17 Jun 2019

Common traits keep many patients with knee cartilage issues from participating in clinical trials

Some of the most common traits among patients with cartilage issues in the knee are excluding them from participating in clinical trials because the trial outcomes might not yield the optimum results for new methods of cartilage regeneration, according to a Penn Medicine study published in Regenerative Medicine.

16 Jun 2019

Warning issued by FDA after patient dies following fecal transplant

A warning from the U.S FDA was issued yesterday after a patient died due to receiving a fecal transplant that contained drug-resistant bacteria.

14 Jun 2019

Vitamin D metabolite may stop mechanism by which cancer cells become drug-resistant

What's good for our bones may also help stop cancer cells that develop resistance to multiple chemotherapy drugs.

14 Jun 2019

Research suggests new way to improve the efficacy of arthritis drug

Attaching a removable lock to an arthritis drug can make it safer and more effective, according to a new study publishing June 13 in the open-access journal PLOS Biology led by Wen-Wei Lin of Kaohsiung Medical University, Taiwan.

From PLOS ONE 14 Jun 2019

Experimental antiviral drug cures mice infected with deadly tick-borne virus

Only a few cases of the newly discovered Bourbon virus have been reported, and two of them ended in death, partly because no specific treatments are available for the tick-borne illness.

14 Jun 2019

Heart failure drug could be effective in treating leukemia

Canadian researchers followed their intuition that a drug initially intended for heart failure could be effective in treating cancer. Those efforts have borne fruit, as demonstrated by their work published in the Journal of Experimental and Clinical Cancer Research.

13 Jun 2019

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

The results of a randomized controlled trial presented today at the Annual European Congress of Rheumatology demonstrate high levels of treatment success in approximately two thirds of patients despite tapered glucocorticoid discontinuation, while a small loss of disease control was observed at the total study population level.

13 Jun 2019

Identifying colorectal cancer subtypes in patients could help provide better care

Colorectal cancer is the second leading cause of cancer death in the U.S., expected to cause about 51,000 deaths in 2019. But until now, it was unclear which drugs were most effective for which patients.

12 Jun 2019

New intervention shows promise for relief of shoulder pain in wheelchair users with spinal cord injury

A New Jersey team of researchers has reported the successful, long-term relief of chronic refractory shoulder pain in a wheelchair user with spinal cord injury following a single injection of autologous, micro-fragmented adipose tissue into the affected shoulder joint.

12 Jun 2019

Efficacy News and Research

New type of treatment for osteoarthritis shows promise for use in humans

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Highlights and key takeaways from the 2019 Boston Bacterial Meeting (BBM)

Researchers discover redundancies in immune cells

Anti-aging study wins grant from William and Ella Owens Medical Research Foundation

Consortium receives EU grant to develop new treatment for leishmaniasis

Researchers develop promising reconstruction method based on 3D-printed esophageal grafts

FDA approves first non-insulin drug for treatment of pediatric patients with type 2 diabetes

New experimental system can rapidly assess pathogenic effects of a drug on baby's brain

Topical cream found to be effective in reversing the effects of vitiligo

Harvard chemists achieve landmark in drug discovery with synthesis of potent anti-cancer agent

Common traits keep many patients with knee cartilage issues from participating in clinical trials

Warning issued by FDA after patient dies following fecal transplant

Vitamin D metabolite may stop mechanism by which cancer cells become drug-resistant

Research suggests new way to improve the efficacy of arthritis drug

Experimental antiviral drug cures mice infected with deadly tick-borne virus

Heart failure drug could be effective in treating leukemia

Study shows high levels of success in most patients despite tapered glucocorticoid discontinuation

Identifying colorectal cancer subtypes in patients could help provide better care

New intervention shows promise for relief of shoulder pain in wheelchair users with spinal cord injury

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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