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Investigators discover biological explanation for why low levels of oxygen advance SMA symptoms

Investigators at Nationwide Children's Hospital may have discovered a biological explanation for why low levels of oxygen advance spinal muscular atrophy (SMA) symptoms and why breathing treatments help SMA patients live longer. The findings appear in Human Molecular Genetics.

22 Aug 2012

Deep abdominal muscle activation lessens lower back pain

Improving transversus abdominis slide appears to be associated with clinically important long-term pain reduction in people experiencing lower back pain, researchers report.

21 Aug 2012

Muscle synergies activated in altered ways after stroke

The simple act of picking up a pencil requires the coordination of dozens of muscles: The eyes and head must turn toward the object as the hand reaches forward and the fingers grasp it. To make this job more manageable, the brain's motor cortex has implemented a system of shortcuts. Instead of controlling each muscle independently, the cortex is believed to activate muscles in groups, known as "muscle synergies." These synergies can be combined in different ways to achieve a wide range of movements.

21 Aug 2012

Working out during pregnancy wards off muscle pain

Not enough healthy pregnant women are doing the recommended amount of physical exercise, suggest study findings.

20 Aug 2012

Juventas commences treatment in JVS-100 Phase II STOP-HF trial for late stage heart failure

Juventas Therapeutics, a privately-held clinical-stage company developing novel regenerative therapies for treatment of cardiovascular disease, reports treating the first patient in its STOP-HF trial.

20 Aug 2012

CDC reports worst West Nile virus outbreak in the U.S.

This past year's mild winter and wet spring could be contributing to the worst West Nile virus outbreak since the disease was first detected in the United States in 1999. According to the Centers for Disease Control and Prevention, there have been more cases of the virus so far this year than any year. As of August 14, almost 700 cases had been reported across the nation, including 26 deaths. This year also marks the earliest reported case of West Nile virus in New Jersey.

18 Aug 2012

Pennsylvania Department of Health reports four confirmed and six probable cases of H3N2v flu

The Pennsylvania Department of Health today reported four confirmed and six probable human cases of influenza due to a new strain of the flu known as H3N2v.

18 Aug 2012

Mylan Pharmaceuticals receives FDA approval for pioglitazone tablets to treat type 2 diabetes

The U.S. Food and Drug Administration today approved the first generic version of Actos (pioglitazone hydrochloride) tablets. Along with diet and exercise, pioglitazone is used to improve blood glucose control in adults with type 2 diabetes.

18 Aug 2012

Dendritic cells protect against MS in mouse model

In multiple sclerosis, the immune system attacks nerves in the brain and spinal cord, causing movement problems, muscle weakness and loss of vision. Immune cells called dendritic cells, which were previously thought to contribute to the onset and development of multiple sclerosis, actually protect against the disease in a mouse model, according to a study published by Cell Press in the August issue of the journal Immunity.

17 Aug 2012

Johns Hopkins undergraduates invent disposable suturing tool

After a surgeon stitches up a patient's abdomen, costly complications -- some life-threatening -- can occur. To cut down on these postoperative problems, Johns Hopkins undergraduates have invented a disposable suturing tool to guide the placement of stitches and guard against the accidental puncture of internal organs.

17 Aug 2012

'Yoga for Healthy Lower Backs' likely to be cost effective for both NHS and wider society

Specialised group yoga classes could provide a cost-effective way of treating patients with chronic or recurrent low back pain, according to the UK's largest ever study of the benefits of yoga.

17 Aug 2012

Study looks at differences in brain structure between karate practitioners

Brain scans have revealed distinctive features in the brain structure of karate experts, which could be linked to their ability to punch powerfully from close range. Researchers from Imperial College London and UCL (University College London) found that differences in the structure of white matter - the connections between brain regions - were correlated with how black belts and novices performed in a test of punching ability.

16 Aug 2012

Passenger deletions that deactivate essential genes provide new opportunity to strike cancer

Genomic deletions promote cancer by carving up or eliminating tumor-suppressor genes, but now scientists report in the journal Nature that the collateral damage they inflict on neighboring genes exposes cancer cells to vulnerabilities and new avenues for attack.

16 Aug 2012

Yo-yo dieting does not negatively affect metabolism or ability to lose weight long term

Yo-yo dieting - the repetitive loss and regain of body weight, also called weight cycling - is prevalent in the Western world, affecting an estimated 10 percent to 40 percent of the population. The degree to which weight cycling may impact metabolism or thwart a person's ability to lose weight in the long run has been unclear - until now.

16 Aug 2012

Mechanism for chemotherapy resistance identified

Researchers have identified that chemotherapy induces subsequent treatment resistance through damaging healthy tissue, which in turn secretes novel factors that sustain the growth of residual tumor cells.

15 Aug 2012

Excessive cleanliness may be bad for your health

Research suggests that the antibacterial chemical triclosan, commonly used in personal-care products and antibacterial soaps, may impair the function of cardiac and skeletal muscle.

15 Aug 2012

No aping around after anesthetic combination

A combination of medetomidine and ketamine administered intramuscularly to chimpanzees, orangutans, and gorillas results in reliable immobilization for both the animals and personnel handling them, report researchers.

15 Aug 2012

Kessler Foundation investigates Ekso's new capabilities for autonomous use by people with SCI

Kessler Foundation has begun testing the upgraded Ekso in individuals unable to walk due to spinal cord injury. Ekso, a wearable, battery-powered robotic exoskeletal device, has been undergoing clinical investigation at Kessler since October 2011, when the research team received the second commercial unit distributed by Ekso Bionics.

15 Aug 2012

Trial to test efficacy of NeuRx Diaphragm Pacing System in people with Lou Gehrig's disease

The Muscular Dystrophy Association (MDA) and The ALS Association today announced a joint commitment to provide funding for a phase 2 clinical trial that will test efficacy of the NeuRx Diaphragm Pacing System (DPS) in people with amyotrophic lateral sclerosis (ALS).

15 Aug 2012

Neurostimulator a significant step in treating sleep apnea

At Charité - Universitätsmedizin Berlin the first tongue pacemaker was implanted Europe-wide that prevents pauses in breathing during sleep and helps against snoring. Physicians at the Department of Otolaryngology used the device for a patient who suffers from obstructive sleep apnea syndrome.

15 Aug 2012

Muscle News and Research

Investigators discover biological explanation for why low levels of oxygen advance SMA symptoms

Deep abdominal muscle activation lessens lower back pain

Muscle synergies activated in altered ways after stroke

Working out during pregnancy wards off muscle pain

Juventas commences treatment in JVS-100 Phase II STOP-HF trial for late stage heart failure

CDC reports worst West Nile virus outbreak in the U.S.

Pennsylvania Department of Health reports four confirmed and six probable cases of H3N2v flu

Mylan Pharmaceuticals receives FDA approval for pioglitazone tablets to treat type 2 diabetes

Dendritic cells protect against MS in mouse model

Johns Hopkins undergraduates invent disposable suturing tool

'Yoga for Healthy Lower Backs' likely to be cost effective for both NHS and wider society

Study looks at differences in brain structure between karate practitioners

Passenger deletions that deactivate essential genes provide new opportunity to strike cancer

Yo-yo dieting does not negatively affect metabolism or ability to lose weight long term

Mechanism for chemotherapy resistance identified

Excessive cleanliness may be bad for your health

No aping around after anesthetic combination

Kessler Foundation investigates Ekso's new capabilities for autonomous use by people with SCI

Trial to test efficacy of NeuRx Diaphragm Pacing System in people with Lou Gehrig's disease

Neurostimulator a significant step in treating sleep apnea

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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