Immune System News and Research

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Post-surgical opioids can prolong pain for more than three weeks, study shows

Giving opioids to animals to quell pain after surgery prolongs pain for more than three weeks and primes specialized immune cells in the spinal cord to be more reactive to pain, according to a new study by the University of Colorado Boulder.

16 Apr 2018

MD Anderson research provides insight into memory T cell development and disease relapse

Just like people, some T cells have excellent memories. These subtypes known as memory T cells may explain why some immunotherapies are more effective than others and potentially lead to researchers designing more effective studies using combination checkpoint blockade treatments, according to experts at The University of Texas MD Anderson Cancer Center.

16 Apr 2018

Precancerous colon polyps in Lynch syndrome patients display immune activation

Colon polyps from patients with Lynch syndrome, a hereditary condition that raises colorectal cancer risk, display immune system activation well before cancer development, according to research from The University of Texas MD Anderson Cancer Center.

16 Apr 2018

Engineered immune cells clear deadly pediatric brain tumor in mice

Engineered human immune cells can vanquish a deadly pediatric brain tumor in a mouse model, a study from the Stanford University School of Medicine has demonstrated.

16 Apr 2018

Novel disease model for ALS and MS can be used to develop new immunotherapies

Researchers at Karolinska Institutet in Sweden have developed a new disease model for neurodegenerative diseases such as ALS and MS that can be used to develop new immunotherapies. The model is described in a publication in the scientific journal Nature Immunology.

16 Apr 2018

Anti-PD-1 treatment reduces tumor size and post-surgical relapse of lung cancer

A drug given to early stage lung cancer patients before they undergo surgery showed major tumor responses in the removed tumor and an increase in anti-tumor T-cells that remained after the tumor was removed, which resulted in fewer relapse cases in the patients.

16 Apr 2018

New tool developed to protect women from HIV infection

Scientists at the University of Waterloo have developed a new tool to protect women from HIV infection.

16 Apr 2018

Researchers develop new tool to protect against HIV infection

Researchers at the University of Waterloo have developed a vaginal implant based on the theory of immune quiescence that could prevent women from contracting HIV.

16 Apr 2018

New award will help research into immune system differences that trigger food allergies

Adora A. Lin, M.D., Ph.D., an attending physician in Children's department of Allergy and Immunology, was awarded $240,000 to improve understanding of how children's immune systems tolerate or react to certain food allergens--sometimes triggering a cascade of side effects that can be fatal.

13 Apr 2018

Receptor that detects heat of red chili pepper may help protect the brain after TBI

A receptor on our immune cells that can detect both the heat of a red chili pepper and the extreme physical heat of a pizza oven may help protect the brain following a traumatic brain injury, scientists say.

13 Apr 2018

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body's lymph nodes, which are connected to a network of lymph vessels through which lymphatic fluid flows.

12 Apr 2018

Researchers show how highly contagious norovirus infection starts in mice

Norovirus – the highly contagious gastrointestinal illness best known for spreading rapidly on cruise chips, in nursing homes, schools and other densely populated spaces – kills an estimated 200,000 people annually, mostly in the developing world.

12 Apr 2018

Researchers get one step closer to creating peptide vaccine against atherosclerosis

In the disease atherosclerosis, cholesterol-containing plaques form in vessel walls, causing arteries to narrow and greatly increasing the risk of heart attack and stroke.

12 Apr 2018

Breast cancers more likely to spread after surgery finds study

Breast cancer patients are more likely to experience a return and spread of their cancer within 18 months after a mastectomy or removal of the breast tumour along with healthy breast tissues. The reason for this or this association has been hitherto unexplained. According to a new study from MIT and the Whitehead Institute, the process of healing of the surgical scar after surgery is the cause for spread of the cancer.

12 Apr 2018

Scientists developing new vaccines against heroin and prescription opioids

Heroin and prescription opioid abuse and fatal overdoses are a public health emergency in the United States. Vaccines offer a potential new strategy to treat opioid abuse and prevent fatal opioid overdoses.

12 Apr 2018

Ludwig scientists develop and test individualized ovarian cancer vaccine

A Ludwig Cancer Research study has shown that an entirely new type of personalized cancer vaccine induces novel, potent and clinically effective immune responses in patients receiving a combination of standard therapies for recurrent, stage III and IV ovarian cancer.

11 Apr 2018

New cancer vaccine yields promising results in clinical study

A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania.

11 Apr 2018

Nanotechnology-based treatment approach shown to be effective in mouse models of lung cancer

The most common type of lung cancer, non-small cell lung cancer (NSCLC), continues to be difficult to treat, with five year survival rates of about 36 percent for stage 3A tumors.

11 Apr 2018

Nasal vaccine may suppress peanut allergy in mice, study shows

A vaccine may successfully turn off peanut allergy in mice, a new study shows.Just three monthly doses of a nasal vaccine protected the mice from allergic reactions upon exposure to peanut, according to research from the Mary H. Weiser Food Allergy Center at the University of Michigan.

11 Apr 2018

Scripps Florida researchers awarded $2.875 million to destroy common form of leukemia

Christoph Rader, PhD, associate professor at the Florida campus of The Scripps Research Institute, has been awarded a $2.875 million, five-year grant from the National Cancer Institute to develop unique antibody-drug conjugates engineered to eradicate one of the most common forms of leukemia, chronic lymphocytic leukemia

10 Apr 2018