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Study sheds light on developing more targeted therapies against medulloblastoma

St. Jude Children's Research Hospital scientists have gained ground toward developing more targeted therapies for the most common childhood brain tumor.

10 May 2015

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease.

8 May 2015

Quantitative phosphoproteomic approach to identify targeted cancer therapy

Winner of the Louise Eisenhardt Traveling Scholarship Award, Teresa Purzner, MD, presented her research, Quantitative Phosphoproteomics for Targeted Cancer Therapy.

7 May 2015

NIMH-funded project aims to identify genetic causes of schizophrenia

Researchers at the University of Virginia School of Medicine will seek to identify the genetic causes of schizophrenia as part of a major project funded by the National Institute of Mental Health to better understand how genetic variation in brain cells affects human health and disease.

7 May 2015

Researchers compile new genomic interactions catalogue

New clues about diseases like inflammatory bowel disorder may be found thanks to a new genomic interactions catalogue by a group of researchers in Japan and the United Kingdom. This research will be published on May 4, 2015 in Nature Genetics.

6 May 2015

Researcher reports possible existence of sixth DNA base

DNA (deoxyribonucleic acid) is the main component of our genetic material. It is formed by combining four parts: A, C, G and T (adenine, cytosine, guanine and thymine), called bases of DNA combine in thousands of possible sequences to provide the genetic variability that enables the wealth of aspects and functions of living beings.

6 May 2015

Luxembourg biologists provide complete image of human 'miRNome' in blood samples

In an elaborate study, biologists of the University of Luxembourg have found out that small molecules named microRNAs are, against many hopes, not yet suitable for early diagnosis of skin cancer, as well as supposedly for other types of cancer, in blood samples. For the first time they analysed all microRNAs in the serum of healthy people and thus provided a first complete image of the human "miRNome" in blood samples, in reference to the better-known "genome".

6 May 2015

Researchers study early response of cells to ischemia

A group of researchers from the Lomonosov Moscow State University in collaboration with their Irish colleagues from the University College Cork has studied the early response of cells to ischemia, which is a restriction in blood supply to tissues causing the death of the cell.

6 May 2015

St. Jude scientists develop new computer tool to find DNA duplications and deletions in tumors

St. Jude Children's Research Hospital scientists have developed a significantly better computer tool for finding genetic alterations that play an important role in many cancers but were difficult to identify with whole-genome sequencing.

5 May 2015

Researchers identify mechanism responsible for steroid resistance in leukemia patients

Researchers led by St. Jude Children's Research Hospital scientists have identified a mechanism that helps leukemia cells resist glucocorticoids, a finding that lays the foundation for more effective treatment of cancer and possibly a host of autoimmune diseases.

5 May 2015

Mutations in PARN and RTEL1 associated with familial pulmonary fibrosis, telomere shortening

Researchers at UT Southwestern Medical Center have identified mutations in two genes that cause a fatal lung scarring disease known as familial pulmonary fibrosis.

5 May 2015

Scientists produce low-allergen, low anti-nutritional inhibitor soybean

In the United States, nearly 15 million people and 1 in 13 children suffer from food allergy. In Arizona alone, every classroom contains at least two children with a food allergy. Soybeans are one of the eight foods regulated by the Food Allergen Labeling and Consumer Protection Act, or FALPA. Soybean is a major ingredient in many infant formulas, processed foods and livestock feed used for agriculture. Soybeans contain several allergenic and anti-nutritional proteins that affect soybean use as food and animal feed.

5 May 2015

Frederick Alt honored with 2015 Szent-Györgyi Prize for Progress in Cancer Research

Frederick Alt, PhD, director of the Program in Cellular and Molecular Medicine at Boston Children's Hospital, has been honored with the 2015 Szent-Györgyi Prize for Progress in Cancer Research.

4 May 2015

High Throughput ChIP-seq Assay for Genome-wide Protein-DNA Analysis

Chromatrap®, a business unit of Porvair Sciences, has published a new application note that describes how Chromatrap® ChIP-seq assays now enable unbiased, genome-wide understanding of protein-DNA regulatory networks...

From Chromatrap® - Porvair Sciences Ltd 30 Apr 2015

UTHealth scientists use new methods to explore naturally occurring 'knockout humans'

Researchers at The University of Texas Health Science Center at Houston are helping to make precision medicine a reality by sequencing entire exomes of people to assess chronic disease risk and drug efficacy. The results of a study on this topic were published in Nature Genetics on Monday.

30 Apr 2015

Study finds that gene therapy can clip out genetic material associated with heart failure

Gene therapy can clip out genetic material linked to heart failure and replace it with the normal gene in human cardiac cells, according to a study led by researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

30 Apr 2015

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

Sangamo BioSciences, Inc. announced that data from clinical, preclinical and research-stage programs focused on the development of ZFP Therapeutics will be presented at the 18th Annual Meeting of the American Society of Gene and Cell Therapy

29 Apr 2015

Two world-renowned scientists receive Poland-U.S. Science Award

World-renowned scientists -- Prof. Mariusz Jaskólski of Adam Mickiewicz University in Poznań, Poland, and Dr. Alexander Wlodawer of the National Cancer Institute, USA -- are the first winners of the Poland-U.S. Science Award granted jointly by the Foundation for Polish Science and the American Association for the Advancement of Science, the world's largest scientific association.

29 Apr 2015

New T1D Prevention Initiative launched to identify pathways to prevent type 1 diabetes

As the incidence of type 1 diabetes (T1D) rises worldwide, The Leona M. and Harry B. Helmsley Charitable Trust today announced the launch of an ambitious new T1D Prevention Initiative to investigate the early stages of development of the disease and identify new pathways to prevent it.

28 Apr 2015

Common diabetes medication causes intersex in fish

A medication commonly taken for Type II diabetes, which is being found in freshwater systems worldwide, has been shown to cause intersex in fish -male fish that produce eggs.

27 Apr 2015

Genome News and Research

Study sheds light on developing more targeted therapies against medulloblastoma

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Quantitative phosphoproteomic approach to identify targeted cancer therapy

NIMH-funded project aims to identify genetic causes of schizophrenia

Researchers compile new genomic interactions catalogue

Researcher reports possible existence of sixth DNA base

Luxembourg biologists provide complete image of human 'miRNome' in blood samples

Researchers study early response of cells to ischemia

St. Jude scientists develop new computer tool to find DNA duplications and deletions in tumors

Researchers identify mechanism responsible for steroid resistance in leukemia patients

Mutations in PARN and RTEL1 associated with familial pulmonary fibrosis, telomere shortening

Scientists produce low-allergen, low anti-nutritional inhibitor soybean

Frederick Alt honored with 2015 Szent-Györgyi Prize for Progress in Cancer Research

High Throughput ChIP-seq Assay for Genome-wide Protein-DNA Analysis

UTHealth scientists use new methods to explore naturally occurring 'knockout humans'

Study finds that gene therapy can clip out genetic material associated with heart failure

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

Two world-renowned scientists receive Poland-U.S. Science Award

New T1D Prevention Initiative launched to identify pathways to prevent type 1 diabetes

Common diabetes medication causes intersex in fish

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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