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Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Fungal infections represent an increasing health crisis, especially for immune-deficient patients. American scientists now report in the journal Angewandte Chemie that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action.

21 Sep 2017

Neurohistology: how whole slide scanning impacts workflow

MultiBrain technology can accelerate the R&D preclinical and safety assessment processes many fold and perform them less expensively.

From Huron Technologies 21 Sep 2017

Open your mouth and say goo-goo: Dentists treating ever-younger patients

Allen Barron scrunches up his tiny face and wails as his mother gently tips him backward onto the lap of Jean Calvo, a pediatric dental resident at the University of California-San Francisco.

21 Sep 2017

Researchers identify new genetic test to help predict cancer recurrence

Researchers have discovered a new genetic test which could help predict cancer recurrence - paving the way for more precise, personalized treatments.

21 Sep 2017

Space radiation causes long-term health consequences for astronauts

While people protect their eyes from the sun's radiation during a solar eclipse, NASA's Human Research Program is working to protect the whole human body from radiation in space. Space radiation is dangerous and one of the primary health risks for astronauts.

21 Sep 2017

Caregivers draw support by mapping their relationships

Every time Jacque Pearson tried to devise a plan to move her 81-year-old dad, who has Alzheimer's, from his home in Boise, Idaho, to hers in Denver, she felt stuck. Then, two weeks ago, she had a breakthrough.

21 Sep 2017

UC study finds lower IQ scores in children with increased Manganese levels

A study led by environmental health researchers at the University of Cincinnati College of Medicine finds that children in East Liverpool, Ohio with higher levels of Manganese (Mn) had lower IQ scores. The research appears online in the journal NeuroToxicology, available in advance of publication.

21 Sep 2017

Employer-sponsored health plans spend $6 billion extra on preterm infants, study shows

A new study estimates employer-sponsored health plans spent at least $6 billion extra on infants born prematurely in 2013 and a substantial portion of that sum was spent on infants with major birth defects.

21 Sep 2017

High-functioning social communication skills can buffer negative effects of child shyness

A new study by Yale-NUS College Assistant Professor of Social Sciences Cheung Hoi Shan has discovered that shy children with low English vocabulary skills, can still be popular among their peers if they have high-functioning social communication skills that enable them to engage and interact well with their peers in social settings.

21 Sep 2017

Researchers design novel small antibody fragment with improved crystallizability

Antibodies are a powerful weapon system in defending our body against invaders such as bacteria and viruses. Each antibody consists of four polypeptide chains: two heavy chains and two light chains joined to form a Y-shaped molecule.

21 Sep 2017

Study identifies slowly proliferating and highly invasive melanoma cells

A study conducted at The Wistar Institute has led to the identification of a slowly proliferating and highly invasive melanoma cell subpopulation, characterized by production of a protein associated with invasive behavior. The research was published in the journal Oncogene.

21 Sep 2017

Metabolic changes after quitting could help explain how ill-effects of smoking may be reversible

Even after years of smoking, the body has a remarkable ability to repair itself. Now in a study appearing in ACS' Journal of Proteome Research, scientists report that certain metabolic changes occur soon after quitting, and these changes could help explain how some ill-effects of smoking might be reversible.

21 Sep 2017

BMC researchers studying possibility of weight loss drugs to combat cocaine addiction

Boston Medical Center's psychiatry team is studying a drug called lorcaserin, which targets the brain's serotonin receptors and could help reduce cocaine cravings as well as dampen the rewards associated with taking cocaine.

21 Sep 2017

Study opens new door to potential treatments for highly lethal brain tumors

New research conducted in mice provides evidence that highly lethal brain tumors, called high-grade gliomas, stop growing when deprived of a specific molecule naturally produced when brain cells fire.

21 Sep 2017

JAX professor receives $5.4 million grant to study 'cognitive resilience' to Alzheimer's disease

A new five-year grant totaling $5,382,423 to Jackson Laboratory Assistant Professor Catherine Kaczorowski will fund research to explore why some people with a family history of Alzheimer's disease, and even brain changes associated with the disease, nevertheless manage to maintain their cognitive capabilities.

21 Sep 2017

Communication breakdowns between care facilities can pave way for drug-resistant infection

Communication breakdowns between care facilities can pave the way for outbreaks of infection, according to research on the spread of an extensively drug-resistant bacterium.

21 Sep 2017

New device can monitor mitochondria in the heart to predict cardiac arrest

A new device can assess in real time whether the body's tissues are receiving enough oxygen and, placed on the heart, can predict cardiac arrest in critically ill heart patients, report researchers at Boston Children's Hospital and scientists from Cambridge device maker Pendar Technologies.

21 Sep 2017

MIT engineers design more effective synthetic mRNA delivery system

By delivering strands of genetic material known as messenger RNA into cells, researchers can induce the cells to produce any protein encoded by the mRNA. This technique holds great potential for administering vaccines or treating diseases such as cancer, but achieving efficient delivery of mRNA has proven challenging.

21 Sep 2017

Regeneration ability may lie with the body's innate immune system, study shows

The answer to regenerative medicine's most compelling question -- why some organisms can regenerate major body parts such as hearts and limbs while others, such as humans, cannot -- may lie with the body's innate immune system, according to a new study of heart regeneration in the axolotl, or Mexican salamander, an organism that takes the prize as nature's champion of regeneration.

21 Sep 2017

UCSB scientists receive $9 million NSF funding to develop optical brain-imaging techniques

A multidisciplinary team of researchers, including UC Santa Barbara scientists John Bowers, Michael Goard and Luke Theogarajan, has been awarded $9 million from the National Science Foundation (NSF) to develop and widely share state-of-the-art optical brain-imaging techniques.

21 Sep 2017

Research News and Research

Small-molecule immunotherapeutics could steer immune defense against fungal pathogens

Neurohistology: how whole slide scanning impacts workflow

Open your mouth and say goo-goo: Dentists treating ever-younger patients

Researchers identify new genetic test to help predict cancer recurrence

Space radiation causes long-term health consequences for astronauts

Caregivers draw support by mapping their relationships

UC study finds lower IQ scores in children with increased Manganese levels

Employer-sponsored health plans spend $6 billion extra on preterm infants, study shows

High-functioning social communication skills can buffer negative effects of child shyness

Researchers design novel small antibody fragment with improved crystallizability

Study identifies slowly proliferating and highly invasive melanoma cells

Metabolic changes after quitting could help explain how ill-effects of smoking may be reversible

BMC researchers studying possibility of weight loss drugs to combat cocaine addiction

Study opens new door to potential treatments for highly lethal brain tumors

JAX professor receives $5.4 million grant to study 'cognitive resilience' to Alzheimer's disease

Communication breakdowns between care facilities can pave way for drug-resistant infection

New device can monitor mitochondria in the heart to predict cardiac arrest

MIT engineers design more effective synthetic mRNA delivery system

Regeneration ability may lie with the body's innate immune system, study shows

UCSB scientists receive $9 million NSF funding to develop optical brain-imaging techniques

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