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Studies describe ability of targeted exercise training on cognitive impairment and dementia

Four studies reported today at the Alzheimer's Association International Conference 2012 (AAIC 2012) describe the ability of targeted exercise training to promote improved mental functioning and reduced risk for cognitive impairment and dementia in cognitively healthy older adults and those with mild cognitive impairment (MCI).

16 Jul 2012

Rehabilitation after rotator cuff surgery may be partially to blame for high rates of failed healing

A new Hospital for Special Surgery study suggests that the current rehabilitation used for patients undergoing tendon-bone repairs such as rotator cuff repair may be partially to blame for the high rates of failed healing after surgery. Experiments in a rat model of this injury suggest that immobilizing the limb for four to six weeks after surgery, rather than quickly starting physical therapy, improves healing.

16 Jul 2012

Researchers link newly discovered gene mutations to ALS

Researchers have linked newly discovered gene mutations to some cases of the progressive fatal neurological disease amyotrophic lateral sclerosis - ALS, also known as Lou Gehrig's disease. Shedding light on how ALS destroys the cells and leads to paralysis, the researchers found that mutations in this gene affect the structure and growth of nerve cells.

16 Jul 2012

New noninvasive imaging technique may help detect heart transplant rejection in children

Cardiologists at Washington University School of Medicine in St. Louis have developed a noninvasive imaging technique that may help determine whether children who have had heart transplants are showing early signs of rejection. The technique could reduce the need for these patients to undergo invasive imaging tests every one to two years.

14 Jul 2012

Ajuba protein plays a central role in regulating function of heart stem cells

It is not unusual for babies to be born with congenital heart defects. This is because the development of the heart in the embryo is a process which is not only extremely complex, but also error-prone. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now identified a key molecule that plays a central role in regulating the function of stem cells in the heart.

14 Jul 2012

WUSM receives NHLBI grant to study heart disease in patients with diabetes

Researchers at Washington University School of Medicine in St. Louis have received a $4.7 million grant from the National Heart, Lung, and Blood Institute to investigate heart disease in patients with diabetes.

14 Jul 2012

Obesity-fighting tissue in humans is actually not quite brown, says study

The calorie-burning and heat-generating brown fat found in full-grown humans is actually not quite brown; it's beige. So says a new study reported on July 12th in the journal Cell, a Cell Press publication, in which researchers fully characterize this promising obesity-fighting tissue in both mice and humans for the first time.

14 Jul 2012

Scientists isolate new type of energy-burning fat cell

Scientists at Dana-Farber Cancer Institute have isolated a new type of energy-burning fat cell in adult humans which they say may have therapeutic potential for treating obesity.

13 Jul 2012

Scientists capture high-quality images of immune cell trafficking in a beating heart

Blood flow to the heart often is interrupted during a heart attack or cardiac surgery. But when blood flow resumes, the heart may still falter. That's because collateral damage can occur as blood re-enters the heart, potentially slowing recovery and causing future cardiac troubles.

12 Jul 2012

Obama administration's intellectual property policy inflating medical costs abroad

Noting that the Supreme Court last week upheld the Obama administration's Affordable Health Act, Huffington Post reporters Zach Carter and Sabrina Siddiqui write in this Huffington Post editorial that "while the president has focused on lowering health care costs at home, he has repeatedly sought to impose higher drug prices abroad." They add, "For pharmaceutical companies, that has meant steady profits, but for the global poor in desperate need of affordable drugs, those lofty prices are often a matter of life and death."

12 Jul 2012

Communication between brain and muscle cells is short-lived without LRP4 protein

Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues to ensure the conversation is robust.

12 Jul 2012

TGen's customized procedure produces high amounts of exosomes for treatment of CKD

Researchers at the Translational Genomics Research Institute (TGen) have developed a method of isolating biospecimens that could lead to a less costly, less invasive and more accurate way of diagnosing chronic kidney disease, or CKD.

12 Jul 2012

BioControl Medical receives FDA approval to initiate second phase of CardioFit study for heart failure

BioControl Medical has announced U.S. Food and Drug Administration approval to begin the second phase of INOVATE-HF (INcrease Of VAgal TonE in Heart Failure), a global, multi-center, investigational device exemption (IDE) clinical study of the company's CardioFit system for heart failure.

12 Jul 2012

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Two powerful brain chemical systems work together to paralyze skeletal muscles during rapid eye movement (REM) sleep, according to new research in the July 11 issue of The Journal of Neuroscience. The finding may help scientists better understand and treat sleep disorders, including narcolepsy, tooth grinding, and REM sleep behavior disorder.

12 Jul 2012

Experts call for add-on to athletes’ cardiac screening

Modified echocardiography should be included as part of the screening process for athletes at risk for sudden cardiac death, say researchers presenting at the annual meeting of the American Society of Echocardiography in Cincinnati, Ohio, USA.

11 Jul 2012

Oligodendroglia cells: An interview with Jeffrey Rothstein

There are three principle cells in the brain: neurons and two types of glial cells. One type is called an astrocyte. These were well known to inactivate neurotransmitters like glutamate, and provide metabolic support to neurons.

11 Jul 2012

BWH performs New England's first implant of SynCardia temporary Total Artificial Heart

SynCardia Systems, Inc., manufacturer of the world's first and only FDA, Health Canada and CE (Europe) approved Total Artificial Heart, announced today that Harvard-affiliated Brigham and Women's Hospital in Boston has performed New England's first implant of the SynCardia temporary Total Artificial Heart.

11 Jul 2012

Courtagen launches nucSEEKPDx assay

Courtagen Life Sciences, Inc., a privately held life sciences company that provides innovative proteomic and genomic products and services to the life sciences industry, today announced the expansion of their genetic test menu. The new genetic test, nucSEEKPDx, will sequence approximately 1,100 nuclear genes constituting the mitochondrial exome, which encodes the vast majority of proteins found in the mitochondrion. This test is by far the most comprehensive test on the market for the management of mitochondrial disorders.

11 Jul 2012

HIV and AIDS treatment: An interview with Charles Flexner, MD

The best estimates at the moment reckon that there are about 25 million people infected with HIV. Most of those are in resource-limited settings, including sub-Saharan Africa, South East Asia and India.

11 Jul 2012

Being overweight may actually benefit some cardiac patients

A high body mass index and large waist circumference are associated with improved outcomes in both men and women with heart failure, research shows.

10 Jul 2012

Muscle News and Research

Studies describe ability of targeted exercise training on cognitive impairment and dementia

Rehabilitation after rotator cuff surgery may be partially to blame for high rates of failed healing

Researchers link newly discovered gene mutations to ALS

New noninvasive imaging technique may help detect heart transplant rejection in children

Ajuba protein plays a central role in regulating function of heart stem cells

WUSM receives NHLBI grant to study heart disease in patients with diabetes

Obesity-fighting tissue in humans is actually not quite brown, says study

Scientists isolate new type of energy-burning fat cell

Scientists capture high-quality images of immune cell trafficking in a beating heart

Obama administration's intellectual property policy inflating medical costs abroad

Communication between brain and muscle cells is short-lived without LRP4 protein

TGen's customized procedure produces high amounts of exosomes for treatment of CKD

BioControl Medical receives FDA approval to initiate second phase of CardioFit study for heart failure

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Experts call for add-on to athletes’ cardiac screening

Oligodendroglia cells: An interview with Jeffrey Rothstein

BWH performs New England's first implant of SynCardia temporary Total Artificial Heart

Courtagen launches nucSEEKPDx assay

HIV and AIDS treatment: An interview with Charles Flexner, MD

Being overweight may actually benefit some cardiac patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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