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Super-resolution imaging unlocks the role of transporter nanoclusters in tumor metabolism

Serine serves as a metabolic nexus in tumors, coordinating one-carbon metabolism, nucleotide synthesis, and redox regulation. In recent years, targeting the serine metabolic pathway, particularly the rate-limiting enzyme PHGDH, has attracted considerable attention as a promising anticancer strategy.

29 Sep 2025

Can roselle help fight inflammation? New review suggests strong potential

A new review highlights the anti-inflammatory potential of Hibiscus sabdariffa (roselle), synthesizing evidence from 25 studies published between 2019 and 2024. Most findings are from preclinical models, but they point to promising roles in cardiovascular, metabolic, neuroprotective, and anticancer health.

28 Sep 2025

Stereotactic body radiation therapy and surgery show similar outcomes for early lung cancer

Researchers from The University of Texas MD Anderson Cancer Center will present new data at the American Society for Radiation Oncology (ASTRO) 2025 Annual Meeting demonstrating that stereotactic body radiation therapy (SBRT) and surgery achieved similar survival outcomes at 10-year follow-up for patients with early-stage non-small cell lung cancer, with radiation offering quality-of-life benefits.

26 Sep 2025

Engineers create designer biobots using human lung cells

A brand-new engineering approach to generate "designer" biological robots using human lung cells is underway in Carnegie Mellon University's Ren lab.

26 Sep 2025

IGF2BP3 protein drives leukemia growth by linking metabolism and RNA control

Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying RNA to stay one step ahead.

26 Sep 2025

Single-cell RNA sequencing reveals key genes and potential targeted drugs for OA treatment

Researchers from the Department of Orthopedics at Taicang TCM Hospital Affiliated to Nanjing University of Chinese Medicine have made significant strides in understanding the molecular mechanisms underlying osteoarthritis (OA).

26 Sep 2025

Natural psychoactive molecule DMT reduces harmful effects of stroke in animal models

DMT, or dimethyltryptamine is a natural psychoactive molecule found in many plants and mammals. According to an article published in Science Advances, researchers from the HUN-REN BRC Institute of Biophysics and Semmelweis University Heart and Vascular Centre found that DMT reduces the harmful effects of stroke in animal models and cell culture experiments.

26 Sep 2025

Optogenetics and artificial intelligence open path to personalized Parkinson’s treatment

Globally recognized figures like Muhammad Ali and Michael J. Fox have long suffered from Parkinson's disease. The disease presents a complex set of motor symptoms, including tremors, rigidity, bradykinesia, and postural instability.

26 Sep 2025

New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies

Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers like lung and prostate cancer.

26 Sep 2025

Breakthrough in predicting Parkinson’s and dementia in people with REM sleep behavior disorder

An international research team led by Université de Montréal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.

26 Sep 2025

WHO issues guidance for 2026 flu vaccine formulation in the southern hemisphere

The World Health Organization (WHO) today announced its recommendations for the viral composition of influenza vaccines for use in the 2026 influenza season in the southern hemisphere.

26 Sep 2025

Active music therapy offers greater pain relief for hospital patients

A new study from University Hospitals Connor Whole Health found that music therapy interventions involving singing, active instrument play, and relaxation/imagery may be more effective for reducing pain intensity than receptive interventions only involving live or recorded music listening among hospitalized patients with moderate-to-severe pain.

25 Sep 2025

Researchers develop tool to predict how patients will respond to common multiple sclerosis drug

Brazilian researchers, in partnership with French institutions, have developed a tool that can predict how patients will respond to natalizumab, one of the most commonly used drugs for treating multiple sclerosis.

25 Sep 2025

Mucins show promise in preventing Salmonella infections

Mucus is more than just a sticky substance: It contains a wealth of powerful molecules called mucins that help to tame microbes and prevent infection.

25 Sep 2025

Patient-derived organoids advance cancer therapy and vaccines

Tiny, three-dimensional organoid models are reshaping cancer research by recreating the intricate architecture and diversity of human tumors.

25 Sep 2025

Antidepressant fluoxetine alters brain energy use and boosts neural plasticity

A new study shows that the widely used antidepressant fluoxetine does more than boost serotonin levels: it changes how brain cells manage their energy and rebuild their connections, potentially helping the brain "loosen up" and adapt during depression treatment.

25 Sep 2025

Lysosomal activity in worms linked to transgenerational extension of lifespan

In the Wang Lab, it's not unusual for worms to live for a long time. HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing an enzyme in the lysosomes of the roundworm C. elegans, they can extend the worm's life by up to 60 percent.

25 Sep 2025

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Scientists conducted a multiomics study of the world’s oldest verified person (117 years), uncovering protective genetic, immune, metabolic, microbiome, and epigenetic traits that supported her exceptional longevity. These findings highlight how aging and disease may, under rare circumstances, be decoupled.

25 Sep 2025

UdeM studies make a major breakthrough in predicting neurodegenerative diseases

An international research team led by Université de Montréal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.

25 Sep 2025

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

This pilot study found that urinary metabolites of organophosphate pesticides were linked to reduced sperm motility in healthy young men, though results were preliminary. Oxidative stress did not explain the association, suggesting other biological pathways may be involved.

25 Sep 2025

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B Cell News and Research

Super-resolution imaging unlocks the role of transporter nanoclusters in tumor metabolism

Can roselle help fight inflammation? New review suggests strong potential

Stereotactic body radiation therapy and surgery show similar outcomes for early lung cancer

Engineers create designer biobots using human lung cells

IGF2BP3 protein drives leukemia growth by linking metabolism and RNA control

Single-cell RNA sequencing reveals key genes and potential targeted drugs for OA treatment

Natural psychoactive molecule DMT reduces harmful effects of stroke in animal models

Optogenetics and artificial intelligence open path to personalized Parkinson’s treatment

New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies

Breakthrough in predicting Parkinson’s and dementia in people with REM sleep behavior disorder

WHO issues guidance for 2026 flu vaccine formulation in the southern hemisphere

Active music therapy offers greater pain relief for hospital patients

Researchers develop tool to predict how patients will respond to common multiple sclerosis drug

Mucins show promise in preventing Salmonella infections

Patient-derived organoids advance cancer therapy and vaccines

Antidepressant fluoxetine alters brain energy use and boosts neural plasticity

Lysosomal activity in worms linked to transgenerational extension of lifespan

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

UdeM studies make a major breakthrough in predicting neurodegenerative diseases

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

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