Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

A promising strategy to improve functional capacity of damaged muscle

Muscle is the largest organ that accounts for 40% of body mass and plays an essential role in maintaining our lives.

21 Feb 2021

Highly sensitive blood test for cancer wins 2021 Top 10 Clinical Research Achievement Award

Cancer biologists at Weill Cornell Medicine have been awarded a 2021 Top 10 Clinical Research Achievement Award from the Clinical Research Forum for their study last year describing a highly sensitive blood test for monitoring cancer progression and relapse.

20 Feb 2021

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

The first randomized Phase II clinical trial to report on single and combined neoadjuvant immune checkpoint inhibitor therapy in stage I-III non-small cell lung cancer (NSCLC) found combination therapy produced a significant clinical benefit, as assessed by major pathologic response (MPR) rate, as well as enhanced tumor immune cell infiltration and immunological memory.

18 Feb 2021

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer

Urinalysis has long been a staple of physical exams to detect and manage a number of diseases and disorders, but not cancer.

18 Feb 2021

New 3D imaging technique helps detect breast cancer, COVID-19, other diseases

A research team led by UMass Lowell is pioneering a new 3D imaging technique to better detect breast cancer and other diseases, including COVID-19.

17 Feb 2021

Molecular imaging can predict response to novel metastatic breast cancer treatment

Molecular imaging can successfully predict response to a novel treatment for ER-positive, HER2-negative metastatic breast cancer patients who are resistant to hormonal therapy.

17 Feb 2021

Pediatric brain tumors can be classified using diffusion weighted imaging and machine learning

Diffusion weighted imaging and machine learning can successfully classify the diagnosis and characteristics of common types of pediatric brain tumors a UK-based multi-center study, including WMG at the University of Warwick has found.

15 Feb 2021

Researchers study host and viral transcriptomes in tandem to shed light on SARS-CoV-2 infection

In a new study, researchers discuss the use of simultaneous sequencing of both human and viral genes to better understand SARS-CoV-2's infection pathway.

15 Feb 2021

Liquid biopsy can help gauge the effectiveness of therapy for colorectal cancer

A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor.

14 Feb 2021

New urine test could avoid unnecessary prostate cancer biopsies

A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients.

11 Feb 2021

Study elucidates the mode of action of SGLT2 inhibitors in diabetes

Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown.

8 Feb 2021

HKBU and CUHK jointly develop Spermine Risk Score for diagnosis of prostate cancer

Researchers from Hong Kong Baptist University and the Faculty of Medicine at The Chinese University of Hong Kong have jointly developed the Spermine Risk Score which, coupled with the use of a urine test, provides a non-invasive and more reliable method for the diagnosis of prostate cancer.

8 Feb 2021

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

A study by Mayo Clinic researchers published in Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells.

3 Feb 2021

Combining PD-1 and VEGF inhibitors with chemotherapy can help control cholangiocarcinoma

Cholangiocarcinoma (CCA) is considered as a diverse group of epithelial cancers characterized by poor outcomes. Cholangiocarcinoma can be divided into three types according to the original position: Intrahepatic Cholangiocarcinoma (ICC), Perihilar Cholangiocarcinoma (PCC), and Distal Extrahepatic Tumors (DET).

3 Feb 2021

Study: MRI is reliable for intrapelvic T staging of neuroendocrine carcinoma

Oncotarget recently published "Neuroendocrine carcinoma of uterine cervix findings shown by MRI for staging and survival analysis – Japan multicenter study" which reported that to investigate neuroendocrine carcinoma of the uterine cervix cases for MRI features and staging, as well as pathological correlations and survival.

2 Feb 2021

New approach to capture natural killer cells and harvest cancer-killing packets

Building on the promise of emerging therapies to deploy the body's "natural killer" immune cells to fight cancer, researchers at the University of Michigan Rogel Cancer Center and U-M College of Engineering have gone one step further.

28 Jan 2021

Scientist wins 2021 Pioneer in Basic Science Award for breakthrough research on the inner ear

When Andrew Griffith, MD, PhD, looks at the inner ear, he sees what he describes as "an engineering marvel."

28 Jan 2021

Initial stages of breast cancer could be detected more accurately with new proteomics-based technology

Breast cancer, even at its initial stages, could be detected earlier and more accurately than current techniques using blood samples and a unique proteomics-based technology, according to findings of a study led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

26 Jan 2021

Patient-specific model is needed to understand cancer cells and their impacts

Despite cancer being a leading cause of death worldwide, treatment options for many types of cancers remain limited. This is partly due to the in vitro tools used to model cancers, which cannot adequately predict the behavior of a cancer or its sensitivity to drugs.

22 Jan 2021

Dynamic, customized treatment approaches for gastroesophageal cancers may improve survival rates

A phase 2 clinical trial providing personalized treatments based on the genetic profile of metastatic tumors in gastroesophageal cancers has found that using customized treatment approaches, and adapting them over time as tumors become resistant, led to higher rates of survival compared to historical controls.

21 Jan 2021