Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Novel glucose-sensitive membrane offers improved insulin regulation for diabetic patients

For years, glucose-sensitive membranes have been a key focus for improving controlled insulin release in diabetes treatments.

9 Dec 2024

The brain’s hunger switch: TRH neurons hold the key to obesity therapies

Scientists uncover how TRH neurons suppress hunger by inhibiting AgRP neurons, advancing our understanding of GLP-1-based obesity treatments.

9 Dec 2024

New guidelines developed for the diagnosis and management of premature ovarian insufficiency

New guidelines on the diagnosis and management of premature ovarian insufficiency (POI) – developed by the Centre for Research Excellence in Women's Health in Reproductive Life (CRE-WHiRL) at Monash University, and key international women's health organizations with an international team of experts including women with lived experience – will be published today (TBC) simultaneously in three leading journals.

9 Dec 2024

Early bilateral oophorectomy linked to increased Alzheimer's disease risk

Women with early bilateral oophorectomy face higher Alzheimer's risk, especially with APOE4 allele; education and hormone therapy may offer resilience.

9 Dec 2024

Depression genes amplify women's heart disease risk

Study reveals a sex-specific link between genetic risks for psychiatric disorders and cardiovascular diseases (CVDs), with women showing a higher risk of atrial fibrillation, coronary artery disease, and heart failure linked to genetic predisposition to major depression. Menopause and modifiable factors like BMI and smoking amplify these risks.

8 Dec 2024

Study reveals brain structure differences in women with peripartum depression

Researchers have identified structural grey matter differences in the brains of women with a history of peripartum depression and those without within a group of major depressive disorder patients.

6 Dec 2024

Researchers map the circadian clock in the fly brain

All animals including humans are subject to daily rhythms in their activity and sleep, hunger, metabolism, and reproduction.

6 Dec 2024

Early ovarian removal and APOE4 increase Alzheimer's risk in women

New research published by a team of researchers from the University of Toronto in collaboration with colleagues from the University of Alberta has found that women who have had both ovaries surgically removed before the age of 50 and carry a variant of the apolipoprotein gene, the APOE4 allele, are at high risk of late-life Alzheimer disease (AD). Use of hormone therapy mitigates this risk.

5 Dec 2024

Concerns grow over accuracy and safety of direct-to-consumer health tests

Better information and regulation are essential to protect consumers from potential harms of tests advertised directly to consumers, argue experts in The BMJ today.

5 Dec 2024

Discovery of leptin-responsive neurons offers new hope for obesity treatment

Obesity affects a staggering 40 percent of adults and 20 percent of children in the United States. While some new popular therapies are helping to tackle the epidemic of obesity, there is still so much that researchers do not understand about the brain-body connection that regulates appetite.

5 Dec 2024

National trial investigates device to restore ovulation in women with PCOS

Physicians at the University of Oklahoma Health Sciences in Oklahoma City are leading a national clinical trial to help women with polycystic ovary syndrome (PCOS)-related infertility who want to become pregnant.

5 Dec 2024

Study shows lasting benefits of anti-hormonal therapy in postmenopausal women

Today, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low-risk tumors have a long-term benefit for at least 20 years, while the benefit was more short-term for younger women with similar tumor characteristics who had not yet gone through the menopause.

3 Dec 2024

Report highlights increasing use of targeted therapies before surgery for cancer treatment

Breast, bladder, and pancreatic cancers are increasingly being treated with a broad range of therapies before a patient undergoes surgery, and cancer stage at diagnosis continues to be a leading factor in determining a person's survival rate for all types of cancer, according to the first-ever annual cancer report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) Cancer Programs.

3 Dec 2024

Study links menopause hormone therapy to varied heart and blood clot risks

Research on hormone therapy reveals critical insights into cardiovascular disease risks, guiding clinicians in selecting safer treatment options for menopause.

3 Dec 2024

Spatial transcriptomics uncovers new treatment paths for triple-negative breast cancer

Study uses spatial transcriptomics to map intratumoral heterogeneity and microenvironmental dynamics in triple-negative breast cancer (TNBC). The findings identify nine spatial archetypes and gene signatures linked to immunotherapy response and patient outcomes.

2 Dec 2024

Researchers discover new cause of cytokine storm in COVID-19

As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children's Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause of cytokine storm - the extreme inflammatory response associated with increased risk of death in COVID-19 infection.

2 Dec 2024